Naturally circulating pertactin-deficient strains induce distinct gene expression and inflammatory signatures in human dendritic cells

Autor: Kroes, Michiel M, Miranda-Bedate, Alberto, Hovingh, Elise S, Jacobi, Ronald, Schot, Corrie, Pupo, Elder, Raeven, René H M, van der Ark, Arno A J, van Putten, Jos P M, de Wit, Jelle, Mariman, Rob, Pinelli, Elena

Respiratory infections caused by Bordetella pertussis are reemerging despite high pertussis vaccination coverage. Since the introduction of the acellular pertussis vaccine in the late twentieth century, circulating B. pertussis strains increasingly l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::801a3d4b32a98965ade5f35ad6c156d0
http://hdl.handle.net/10029/625065

Acquisition of C1 inhibitor by Bordetella pertussis virulence associated gene 8 results in C2 and C4 consumption away from the bacterial surface.

Autor: Hovingh, Elise S.^1,2, van den Broek, Bryan¹, Kuipers, Betsy², Pinelli, Elena², Rooijakkers, Suzan H. M.¹, Jongerius, Ilse^1,2 i.jongerius-5@umcutrecht.nl

Publikováno v: PLoS Pathogens. 7/24/2017, Vol. 13 Issue 7, p1-22. 22p.

Detection of opsonizing antibodies directed against a recently circulating Bordetella pertussis strain in paired plasma samples from symptomatic and recovered pertussis patients

Autor: Hovingh, Elise S., Kuipers, Betsy, Bonačić Marinović, Axel A., Jan Hamstra, Hendrik, Hijdra, Danielle, Mughini Gras, Lapo, van Twillert, Inonge, Jongerius, Ilse, van Els, Cecile A.C.M., Pinelli, Elena, One Health Microbieel, dIRAS RA-I&I I&I

Publikováno v: Scientific reports, 8(1):12039. Nature Publishing Group
Scientific Reports, 8(1). NLM (Medline)
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Scientific Reports

Correlates of protection (CoPs) against the highly contagious respiratory disease whooping cough, caused by Bordetella pertussis, remain elusive. Characterizing the antibody response to this pathogen is essential towards identifying potential CoPs. H

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8b0f41b41dd10a4542ee36f5743476f
https://dspace.library.uu.nl/handle/1874/388268

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Virulence Associated Gene 8 of Bordetella pertussis Enhances Contact System Activity by Inhibiting the Regulatory Function of Complement Regulator C1 Inhibitor.

Autor: Hovingh, Elise S., de Maat, Steven, Cloherty, Alexandra P. M., Johnson, Steven, Pinelli, Elena, Maas, Coen, Jongerius, Ilse

Publikováno v: Frontiers in Immunology; 6/4/2018, p1-11, 11p