Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Hovdal D"'
Autor:
Vilahur G; Research Institute, Hospital de la Santa Creu i Sant Pau, IIB-Sant Pau, C/Sant Antoni Mª Claret 167, Barcelona 08025, Spain.; Centro de Investigación Biomédica en Red Cardiovascular (CIBERCV), Instituto de Salud Carlos III, Madrid, Spain., Radike M; Research Institute, Hospital de la Santa Creu i Sant Pau, IIB-Sant Pau, C/Sant Antoni Mª Claret 167, Barcelona 08025, Spain.; Radiology Department, Liverpool Heart and Chest Hospital NHS Foundation Trust, Liverpool, UK., Sutelman P; Research Institute, Hospital de la Santa Creu i Sant Pau, IIB-Sant Pau, C/Sant Antoni Mª Claret 167, Barcelona 08025, Spain., Ben-Aicha S; Research Institute, Hospital de la Santa Creu i Sant Pau, IIB-Sant Pau, C/Sant Antoni Mª Claret 167, Barcelona 08025, Spain., Gutiérrez M; Research Institute, Hospital de la Santa Creu i Sant Pau, IIB-Sant Pau, C/Sant Antoni Mª Claret 167, Barcelona 08025, Spain., Casaní L; Research Institute, Hospital de la Santa Creu i Sant Pau, IIB-Sant Pau, C/Sant Antoni Mª Claret 167, Barcelona 08025, Spain., Hovdal D; DMPK, Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Ongstad EL; Bioscience Cardiovascular, Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, USA., Gabrielsen A; Early Clinical Development, Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Hidalgo A; Radiology Department, Hospital Josep Trueta, Girona, Spain., Fjellström O; Projects, Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Carlsson L; Bioscience Cardiovascular, Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, USA., Badimon L; Research Institute, Hospital de la Santa Creu i Sant Pau, IIB-Sant Pau, C/Sant Antoni Mª Claret 167, Barcelona 08025, Spain.; Centro de Investigación Biomédica en Red Cardiovascular (CIBERCV), Instituto de Salud Carlos III, Madrid, Spain.
Publikováno v:
European heart journal [Eur Heart J] 2024 May 07; Vol. 45 (17), pp. 1553-1567.
Autor:
Inghardt T, Antonsson T, Ericsson C, Hovdal D, Johannesson P, Johansson C, Jurva U, Kajanus J, Kull B, Michaëlsson E, Pettersen A, Sjögren T, Sörensen H, Westerlund K, Lindstedt EL
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2022 Oct 13; Vol. 65 (19), pp. 13482. Date of Electronic Publication: 2022 Oct 03.
Autor:
Inghardt T; Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, 431 50 Mölndal, Gothenburg, Sweden., Antonsson T; Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, 431 50 Mölndal, Gothenburg, Sweden., Ericsson C; Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, 431 50 Mölndal, Gothenburg, Sweden., Hovdal D; Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, 431 50 Mölndal, Gothenburg, Sweden., Johannesson P; Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, 431 50 Mölndal, Gothenburg, Sweden., Johansson C; Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, 431 50 Mölndal, Gothenburg, Sweden., Jurva U; Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, 431 50 Mölndal, Gothenburg, Sweden., Kajanus J; Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, 431 50 Mölndal, Gothenburg, Sweden., Kull B; Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, 431 50 Mölndal, Gothenburg, Sweden., Michaëlsson E; Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, 431 50 Mölndal, Gothenburg, Sweden., Pettersen A; Pharmaceutical Sciences, BioPharmaceuticals R&D, AstraZeneca, 431 50 Mölndal, Gothenburg, Sweden., Sjögren T; Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, 431 50 Mölndal, Gothenburg, Sweden., Sörensen H; Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, 431 50 Mölndal, Gothenburg, Sweden., Westerlund K; Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, 431 50 Mölndal, Gothenburg, Sweden., Lindstedt EL; Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, 431 50 Mölndal, Gothenburg, Sweden.
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2022 Sep 08; Vol. 65 (17), pp. 11485-11496. Date of Electronic Publication: 2022 Aug 25.
Autor:
Poch CM; Medical Department I, Cardiology, Angiology, Pneumology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany., Foo KS; Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden.; Department of Medicine, Karolinska Institutet, Huddinge, Sweden., De Angelis MT; Medical Department I, Cardiology, Angiology, Pneumology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.; Institute of Regenerative Medicine in Cardiology, Technical University of Munich, Munich, Germany., Jennbacken K; Research and Early Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Santamaria G; Medical Department I, Cardiology, Angiology, Pneumology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.; Institute of Regenerative Medicine in Cardiology, Technical University of Munich, Munich, Germany., Bähr A; Medical Department I, Cardiology, Angiology, Pneumology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany., Wang QD; Research and Early Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Reiter F; Medical Department I, Cardiology, Angiology, Pneumology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany., Hornaschewitz N; Medical Department I, Cardiology, Angiology, Pneumology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany., Zawada D; Medical Department I, Cardiology, Angiology, Pneumology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.; Institute of Regenerative Medicine in Cardiology, Technical University of Munich, Munich, Germany., Bozoglu T; Medical Department I, Cardiology, Angiology, Pneumology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany., My I; Medical Department I, Cardiology, Angiology, Pneumology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany., Meier A; Medical Department I, Cardiology, Angiology, Pneumology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.; Institute of Regenerative Medicine in Cardiology, Technical University of Munich, Munich, Germany., Dorn T; Medical Department I, Cardiology, Angiology, Pneumology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.; Institute of Regenerative Medicine in Cardiology, Technical University of Munich, Munich, Germany., Hege S; Medical Department I, Cardiology, Angiology, Pneumology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany., Lehtinen ML; Department of Medicine, Karolinska Institutet, Huddinge, Sweden., Tsoi YL; Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden., Hovdal D; Research and Early Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Hyllner J; Research and Early Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.; Division of Biotechnology, IFM, Linköping University, Linköping, Sweden., Schwarz S; Center for Applied Tissue Engineering and Regenerative Medicine (CANTER), Munich University of Applied Sciences, Munich, Germany., Sudhop S; Center for Applied Tissue Engineering and Regenerative Medicine (CANTER), Munich University of Applied Sciences, Munich, Germany., Jurisch V; Medical Department I, Cardiology, Angiology, Pneumology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany., Sini M; Clinical Pharmacology and Safety Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK., Fellows MD; Clinical Pharmacology and Safety Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK., Cummings M; Western Michigan School of Medicine, Kalamazoo, MI, USA., Clarke J; Procella Therapeutics, Stockholm, Sweden., Baptista R; Procella Therapeutics, Stockholm, Sweden., Eroglu E; Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden., Wolf E; Chair for Molecular Animal Breeding and Biotechnology, Gene Center and Department of Veterinary Sciences, LMU Munich, Munich, Germany., Klymiuk N; Medical Department I, Cardiology, Angiology, Pneumology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.; DZHK (German Centre of Cardiovascular Research), Munich Heart Alliance, Munich, Germany., Lu K; Walter-Brendel-Centre of Experimental Medicine, University Hospital, LMU Munich, Munich, Germany., Tomasi R; Walter-Brendel-Centre of Experimental Medicine, University Hospital, LMU Munich, Munich, Germany., Dendorfer A; DZHK (German Centre of Cardiovascular Research), Munich Heart Alliance, Munich, Germany.; Walter-Brendel-Centre of Experimental Medicine, University Hospital, LMU Munich, Munich, Germany., Gaspari M; Department of Experimental and Clinical Medicine, University of Magna Grecia, Catanzaro, Italy., Parrotta E; Department of Experimental and Clinical Medicine, University of Magna Grecia, Catanzaro, Italy., Cuda G; Department of Experimental and Clinical Medicine, University of Magna Grecia, Catanzaro, Italy., Krane M; DZHK (German Centre of Cardiovascular Research), Munich Heart Alliance, Munich, Germany.; Department of Cardiovascular Surgery, INSURE, German Heart Center Munich, Technical University of Munich, Munich, Germany., Sinnecker D; Medical Department I, Cardiology, Angiology, Pneumology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.; DZHK (German Centre of Cardiovascular Research), Munich Heart Alliance, Munich, Germany., Hoppmann P; Medical Department I, Cardiology, Angiology, Pneumology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany., Kupatt C; Medical Department I, Cardiology, Angiology, Pneumology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany. Christian.Kupatt@tum.de.; DZHK (German Centre of Cardiovascular Research), Munich Heart Alliance, Munich, Germany. Christian.Kupatt@tum.de., Fritsche-Danielson R; Research and Early Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden. Regina.Fritsche-Danielson@astrazenca.com., Moretti A; Medical Department I, Cardiology, Angiology, Pneumology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany. amoretti@mytum.de.; Institute of Regenerative Medicine in Cardiology, Technical University of Munich, Munich, Germany. amoretti@mytum.de.; DZHK (German Centre of Cardiovascular Research), Munich Heart Alliance, Munich, Germany. amoretti@mytum.de., Chien KR; Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden. kenneth.chien@ki.se.; Department of Medicine, Karolinska Institutet, Huddinge, Sweden. kenneth.chien@ki.se., Laugwitz KL; Medical Department I, Cardiology, Angiology, Pneumology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany. KL.Laugwitz@mri.tum.de.; DZHK (German Centre of Cardiovascular Research), Munich Heart Alliance, Munich, Germany. KL.Laugwitz@mri.tum.de.
Publikováno v:
Nature cell biology [Nat Cell Biol] 2022 May; Vol. 24 (5), pp. 659-671. Date of Electronic Publication: 2022 May 12.
Autor:
Bartesaghi S; Metabolism, Research and Early Development Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg SE-43183, Sweden., Wallenius K; Metabolism, Research and Early Development Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg SE-43183, Sweden., Hovdal D; Metabolism, Research and Early Development Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg SE-43183, Sweden., Liljeblad M; Metabolism, Research and Early Development Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg SE-43183, Sweden., Wallin S; Metabolism, Research and Early Development Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg SE-43183, Sweden., Dekker N; Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Barlind L; Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Davies N; Advanced Drug Delivery, Pharmaceutical Science, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Seeliger F; Clinical Pharmacology and Safety Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Winzell MS; Metabolism, Research and Early Development Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg SE-43183, Sweden., Patel S; Moderna, Inc., 200 Technology Square, Cambridge, MA 02139, USA., Theisen M; Moderna, Inc., 200 Technology Square, Cambridge, MA 02139, USA., Brito L; Moderna, Inc., 200 Technology Square, Cambridge, MA 02139, USA., Bergenhem N; Business Development, BioPharmaceuticals R&D, AstraZeneca, Boston, MA, USA., Andersson S; Oligonucleotide Discovery, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Peng XR; Metabolism, Research and Early Development Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg SE-43183, Sweden.
Publikováno v:
Molecular therapy. Nucleic acids [Mol Ther Nucleic Acids] 2022 Apr 18; Vol. 28, pp. 500-513. Date of Electronic Publication: 2022 Apr 18 (Print Publication: 2022).
Mathematical models predicting in vivo pharmacodynamic effects from in vitro data can accelerate drug discovery, and reduce costs and animal use. However, data integration and modeling is non-trivial when more than one drug-target receptor is involve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______610::205c624e1ba822fd22eaf11bbb33e4c8
https://publica.fraunhofer.de/handle/publica/256234
https://publica.fraunhofer.de/handle/publica/256234
Autor:
Davies N; Pharmaceutical Sciences, R&D, AstraZeneca, 43183 Gothenburg, Sweden., Hovdal D; Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, 43183 Gothenburg, Sweden., Edmunds N; Clinical Pharmacology and Safety Sciences, R&D, AstraZeneca, Cambridge SG8 6HB, UK., Nordberg P; Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, 43183 Gothenburg, Sweden., Dahlén A; Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, 43183 Gothenburg, Sweden., Dabkowska A; Pharmaceutical Sciences, R&D, AstraZeneca, 43183 Gothenburg, Sweden., Arteta MY; Pharmaceutical Sciences, R&D, AstraZeneca, 43183 Gothenburg, Sweden., Radulescu A; Forschungszentrum Jülich GmbH, Jülich Centre for Neutron Science at Maier-Leibnitz Zentrum, 85748 Garching, Germany., Kjellman T; Pharmaceutical Sciences, R&D, AstraZeneca, 43183 Gothenburg, Sweden., Höijer A; Pharmaceutical Sciences, R&D, AstraZeneca, 43183 Gothenburg, Sweden., Seeliger F; Clinical Pharmacology and Safety Sciences, R&D, AstraZeneca, 43183 Gothenburg, Sweden., Holmedal E; Clinical Pharmacology and Safety Sciences, R&D, AstraZeneca, 43183 Gothenburg, Sweden., Andihn E; Global Project and Portfolio Management, AstraZeneca, 43183 Gothenburg, Sweden., Bergenhem N; Alliance Management, BioPharmaceuticals R&D, AstraZeneca, Boston, MA 02451, USA., Sandinge AS; Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, 43183 Gothenburg, Sweden., Johansson C; Clinical Pharmacology and Safety Sciences, R&D, AstraZeneca, 43183 Gothenburg, Sweden., Hultin L; Clinical Pharmacology and Safety Sciences, R&D, AstraZeneca, 43183 Gothenburg, Sweden., Johansson M; Clinical Pharmacology and Safety Sciences, R&D, AstraZeneca, 43183 Gothenburg, Sweden., Lindqvist J; Clinical Pharmacology and Safety Sciences, R&D, AstraZeneca, 43183 Gothenburg, Sweden., Björsson L; Clinical Pharmacology and Safety Sciences, R&D, AstraZeneca, 43183 Gothenburg, Sweden., Jing Y; Pharmaceutical Sciences, R&D, AstraZeneca, 43183 Gothenburg, Sweden., Bartesaghi S; Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, 43183 Gothenburg, Sweden., Lindfors L; Pharmaceutical Sciences, R&D, AstraZeneca, 43183 Gothenburg, Sweden., Andersson S; Oligonucleotide Discovery, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, 43183 Gothenburg, Sweden.
Publikováno v:
Molecular therapy. Nucleic acids [Mol Ther Nucleic Acids] 2021 Mar 13; Vol. 24, pp. 369-384. Date of Electronic Publication: 2021 Mar 13 (Print Publication: 2021).
Autor:
Lu, Ruei-Min1 (AUTHOR), Hsu, Hsiang-En1 (AUTHOR), Perez, Ser John Lynon P.1 (AUTHOR), Kumari, Monika2 (AUTHOR), Chen, Guan-Hong1 (AUTHOR), Hong, Ming-Hsiang1 (AUTHOR), Lin, Yin-Shiou1 (AUTHOR), Liu, Ching-Hang1 (AUTHOR), Ko, Shih-Han1 (AUTHOR), Concio, Christian Angelo P.3 (AUTHOR), Su, Yi-Jen2 (AUTHOR), Chang, Yi-Han1 (AUTHOR), Li, Wen-Shan1,3 (AUTHOR) wenshan@gate.sinica.edu.tw, Wu, Han-Chung1,2 (AUTHOR) hcw0928@gate.sinica.edu.tw
Publikováno v:
Journal of Biomedical Science. 9/10/2024, Vol. 31 Issue 1, p1-36. 36p.
Autor:
Bosch, Rolien1,2 (AUTHOR) r.bosch@erasmusmc.nl, Sijbrands, Eric J. G.2 (AUTHOR), Snelder, Nelleke1 (AUTHOR)
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology. Sep2024, Vol. 13 Issue 9, p1488-1502. 15p.
Autor:
Liu, Longying1 (AUTHOR), Ning, Nuoyi1 (AUTHOR), Xu, Simeng1 (AUTHOR), Chen, Dongqing1 (AUTHOR), Zhou, Luping1 (AUTHOR), Guo, Zhimou1,2 (AUTHOR), Liang, Xinmiao1,2 (AUTHOR) liangxinmiao@jcmsc.cn, Ye, Xianlong1 (AUTHOR) yexianlong@jcmsc.cn
Publikováno v:
Microbial Cell Factories. 6/12/2024, Vol. 23 Issue 1, p1-13. 13p.