Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Houzong Yao"'
Autor:
Fangfei Li, Jun Lu, Jin Liu, Chao Liang, Maolin Wang, Luyao Wang, Defang Li, Houzong Yao, Qiulong Zhang, Jia Wen, Zong-Kang Zhang, Jie Li, Quanxia Lv, Xiaojuan He, Baosheng Guo, Daogang Guan, Yuanyuan Yu, Lei Dang, Xiaohao Wu, Yongshu Li, Guofen Chen, Feng Jiang, Shiguo Sun, Bao-Ting Zhang, Aiping Lu, Ge Zhang
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Paclitaxel, a first line chemotherapeutic drug, suffers from poor water solubility and low tissue selectivity. Here, the authors report a water-soluble nucleolin aptamer-paclitaxel conjugate that selectively accumulates in ovarian tumor issues displa
Externí odkaz:
https://doaj.org/article/c74e34d161c444469af0643c90b25955
Publikováno v:
Chemistry & Biodiversity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45665708384189135c3f3a339d6acce4
https://doi.org/10.1002/cbdv.202300477
https://doi.org/10.1002/cbdv.202300477
Publikováno v:
Comprehensive Inorganic Chemistry III ISBN: 9780128231531
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d04ef2625b4713e7070af5e330a24e2
https://doi.org/10.1016/b978-0-12-823144-9.00130-8
https://doi.org/10.1016/b978-0-12-823144-9.00130-8
Publikováno v:
European Journal of Inorganic Chemistry. 26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e35bdaa0f9353ef097db17a85b830ea2
https://doi.org/10.1002/ejic.202200763
https://doi.org/10.1002/ejic.202200763
Synthesis, Characterization, and Cytotoxicity of a Reactive Platinum(IV) Monotrifluoromethyl Complex
Publikováno v:
European Journal of Inorganic Chemistry. 26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b63c31637b9ebda798c5540e6dbc2c48
https://doi.org/10.1002/ejic.202200438
https://doi.org/10.1002/ejic.202200438
Autor:
Houzong Yao, Guangyu Zhu
Publikováno v:
ChemMedChem. 17
The efficacy of platinum drugs is limited by severe side effects, drug resistance, and poor pharmacokinetic properties. Utilizing long-lasting blood components as drug carriers is a promising strategy to improve the circulation half-lives and tumor a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c9fafef21884cf90337c3f3830089e5
https://doi.org/10.1002/cmdc.202200482
https://doi.org/10.1002/cmdc.202200482
Autor:
Cai Li, Zhiqin Deng, Hajime Hirao, Qiyuan Zhou, Shu Chen, Guangyu Zhu, Zoufeng Xu, Zhigang Wang, Houzong Yao
Publikováno v:
Chemical Science
Selective activation of prodrugs at diseased tissue through bioorthogonal catalysis represents an attractive strategy for precision cancer treatment. Achieving efficient prodrug photoactivation in cancer cells, however, remains challenging. Herein, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0e60045afb468fae64711dcd93e5c1f
https://doi.org/10.1039/d0sc06839j
https://doi.org/10.1039/d0sc06839j
Publikováno v:
Dalton Transactions. 50:13737-13747
Carboplatin-based platinum(IV) prodrugs containing axial carboxylates are relatively resistant to reduction to release active platinum(II) species and kill cancer cells. To facilitate the activation process, a boron dipyrromethene (BODIPY) ligand has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f96f6a929cf0fc9faafd6e71622ea2b5
https://doi.org/10.1039/d1dt02362d
https://doi.org/10.1039/d1dt02362d
Publikováno v:
Inorganic Chemistry. 59:11823-11833
Platinum drugs are widely used in clinics to treat various types of cancer. However, a number of severe side effects induced by the nonspecific binding of platinum drugs to normal tissues limit their clinical use. The conversion of platinum(II) drugs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f9b7e7d7534ebd34a420a32226e7441
https://doi.org/10.1021/acs.inorgchem.0c01880
https://doi.org/10.1021/acs.inorgchem.0c01880
Publikováno v:
Inorganic Chemistry. 59:11676-11687
Platinum(IV) complexes containing carboxylate and carbamate ligands at the axial position have been reported previously. A better understanding of the similarity and difference between the two types of ligands will provide us with new insights and mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81a48434d7f5400af8552500cb5510df
https://doi.org/10.1021/acs.inorgchem.0c01541
https://doi.org/10.1021/acs.inorgchem.0c01541