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pro vyhledávání: '"Houyun Teng"'
Autor:
Hui Sun, Yi Cheng, Houyun Teng, Xiaoqi Chen, Xiaokang Niu, Hao Yang, Yu-Ming Cui, Li-Wen Xu, Lei Yang
Publikováno v:
The Journal of Organic Chemistry. 87:13346-13351
An iridium-catalyzed, directing group-enabled site selective intra- and intermolecular silylation of indoles and pyrroles with hydrosilanes has been developed under ligand-free conditions. Fine-tuning of the removable 3-alkyl-2-pyridyl directing grou
Publikováno v:
Current Pharmaceutical Design. 24:4911-4920
Blockade of PD-1/PD-L1 interactions using PD-1/PD-L1 pathway modulators has shown unprecedented clinical efficacy in various cancer models. Current PD-1/PD-L1 modulators approved by FDA are exclusively dominated by therapeutic antibodies. Nevertheles