Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Houyin Zhang"'
Autor:
Ilya B. Novikov, Tajhal Dayaram, Neha Parikh, Griff Weber, Angela D. Wilkins, Scott Spangler, Sam Regenbogen, Ying Chen, Linda Kato, Ana Lelescu, Shenghua Bao, Benjamin J. Bachman, Byung-Kwon Choi, Houyin Zhang, Anbu Karani Adikesavan, Curtis R. Pickering, Lawrence A. Donehower, Meena Nagarajan, Christie M. Buchovecky, Kenneth L. Scott, Jacques L. Labrie, Olivier Lichtarge, Sung Yun Jung, Peter J. Haas, Stephen K. Boyer
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance We adapted natural language processing to the biological literature and demonstrated end-to-end automated knowledge discovery by exploring subtle word connections. General text mining scanned 21 million publication abstracts and selected
Autor:
Xunan Chen, Houyin Zhang
Publikováno v:
International Journal of Modern Physics B. 21:4212-4218
The finite-size scaling functions of thermodynamic functions in anisotropic systems have been shown to be dependent on the spatial anisotropy [X.S. Chen and V. Dohm, Phys. Rev. E 70, 056136 (2004)]. Here we extend this study to the correlation length
Autor:
Lawrence A. Donehower, Curtis R. Pickering, Anbu Karani Adikesavan, Ilya B. Novikov, Linda Kato, Christie M. Buchovecky, Meenakshi Nagarajan, Angela D. Wilkins, Shenghua Bao, Andreas Martin Lisewski, Benjamin J. Bachman, Ying Chen, Sam Regenbogen, Olivier Lichtarge, Sumit Bhatia, María E. Terrón-Díaz, Jacques Joseph Labrie, Griff Weber, Ana Lelescu, Peter J. Haas, Stephen K. Boyer, Scott Spangler, Houyin Zhang
Publikováno v:
KDD
We present KnIT, the Knowledge Integration Toolkit, a system for accelerating scientific discovery and predicting previously unknown protein-protein interactions. Such predictions enrich biological research and are pertinent to drug discovery and the
Literature-based automated discovery of tumor suppressor p53 phosphorylation and inhibition by NEK2.
Autor:
Byung-Kwon Choi, Dayaram, Tajhal, Parikh, Neha, Wilkins, Angela D., Nagarajan, Meena, Novikov, Ilya B., Bachman, Benjamin J., Sung Yun Jung, Haas, Peter J., Labrie, Jacques L., Pickering, Curtis R., Adikesavan, Anbu K., Regenbogen, Sam, Kato, Linda, Lelescu, Ana, Buchovecky, Christie M., Houyin Zhang, Sheng Hua Bao, Boyer, Stephen, Weber, Griff
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 10/16/2018, Vol. 115 Issue 42, p10666-10671, 6p
Autor:
John F. Marko, Houyin Zhang
Publikováno v:
Biophysical Journal. 102(3)
In statistical mechanics, the correlation length measures the distance over which the microscopic variables at different positions are correlated. When we stretch a DNA polymer by using uniform tension, we find that the zero-force correlation length
Publikováno v:
Nucleic acids research, vol 39, iss 13
Nucleic Acids Research
Nucleic Acids Research
Determining numbers of proteins bound to large DNAs is important for understanding their chromosomal functions. Protein numbers may be affected by physical factors such as mechanical forces generated in DNA, e.g. by transcription or replication. We p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::281c95ab188c29395261872606748f4e
https://escholarship.org/uc/item/0dk5h116
https://escholarship.org/uc/item/0dk5h116
Publikováno v:
Biophysical Journal. 100(3)
DNA compaction and chromosome organization involve the dynamic interaction of long DNA molecules and many copies of various proteins. Determining numbers of proteins bound to large DNAs is important to understand their chromosomal functions and prote
Autor:
Houyin Zhang, John F. Marko
Publikováno v:
Physical review. E, Statistical, nonlinear, and soft matter physics. 82(5 Pt 1)
We study a statistical-mechanical model of the binding of DNA-bending proteins to the double helix including applied tension and binding cooperativity effects. Intrinsic cooperativity of binding sharpens force-extension curves and causes enhancement
Autor:
John F. Marko, Houyin Zhang
Publikováno v:
Biophysical Journal. (3):610a
Single-DNA stretching and twisting experiments provide a sensitive means to detect binding of proteins, via detection of their modification of DNA mechanical properties. However, it is often difficult or impossible to determine the numbers of protein