Coactivator-independent vitamin D receptor signaling causes severe rickets in mice, that is not prevented by a diet high in calcium, phosphate, and lactose.

Autor: Doms S; Department of Chronic diseases and metabolism, Laboratory of Clinical and Experimental Endocrinology, KU Leuven, Leuven, Belgium., Verlinden L; Department of Chronic diseases and metabolism, Laboratory of Clinical and Experimental Endocrinology, KU Leuven, Leuven, Belgium., Janssens I; Department of Chronic diseases and metabolism, Laboratory of Clinical and Experimental Endocrinology, KU Leuven, Leuven, Belgium., Vanhevel J; Department of Chronic diseases and metabolism, Laboratory of Clinical and Experimental Endocrinology, KU Leuven, Leuven, Belgium., Eerlings R; Department of Cellular and Molecular Medicine, Laboratory of Molecular Endocrinology, KU Leuven, Leuven, Belgium.; Institute of Applied Microbiology, RWTH Aachen University, Aachen, Germany., Houtman R; Precision Medicine Lab, Oss, The Netherlands., Kato S; Health Sciences Research Center, Iryo Sosei University, Iwaki, Fukuchima, Japan.; Research Institute of Innovative Medicine, Tokiwa Foundation, Iwaki, Fukuchima, Japan., Mathieu C; Department of Chronic diseases and metabolism, Laboratory of Clinical and Experimental Endocrinology, KU Leuven, Leuven, Belgium., Decallonne B; Department of Chronic diseases and metabolism, Laboratory of Clinical and Experimental Endocrinology, KU Leuven, Leuven, Belgium., Carmeliet G; Department of Chronic diseases and metabolism, Laboratory of Clinical and Experimental Endocrinology, KU Leuven, Leuven, Belgium., Verstuyf A; Department of Chronic diseases and metabolism, Laboratory of Clinical and Experimental Endocrinology, KU Leuven, Leuven, Belgium. mieke.verstuyf@kuleuven.be.

Publikováno v: Bone research [Bone Res] 2024 Aug 20; Vol. 12 (1), pp. 44. Date of Electronic Publication: 2024 Aug 20.

Selective Modulation of the Human Glucocorticoid Receptor Compromises GR Chromatin Occupancy and Recruitment of p300/CBP and the Mediator Complex.

Autor: Van Moortel L; VIB-UGent Center for Medical Biotechnology, VIB Institute, Ghent, Belgium; Department of Biomolecular Medicine, Ghent University, Ghent, Belgium., Verhee A; VIB-UGent Center for Medical Biotechnology, VIB Institute, Ghent, Belgium; Department of Biomolecular Medicine, Ghent University, Ghent, Belgium., Thommis J; VIB-UGent Center for Medical Biotechnology, VIB Institute, Ghent, Belgium; Department of Biomolecular Medicine, Ghent University, Ghent, Belgium., Houtman R; Precision Medicine Lab, Oss, The Netherlands., Melchers D; Precision Medicine Lab, Oss, The Netherlands., Delhaye L; VIB-UGent Center for Medical Biotechnology, VIB Institute, Ghent, Belgium; Department of Biomolecular Medicine, Ghent University, Ghent, Belgium., Van Leene C; VIB-UGent Center for Medical Biotechnology, VIB Institute, Ghent, Belgium; Department of Biomolecular Medicine, Ghent University, Ghent, Belgium., Hellemans M; VIB-UGent Center for Medical Biotechnology, VIB Institute, Ghent, Belgium; Department of Biomolecular Medicine, Ghent University, Ghent, Belgium; VIB-UGent Inflammation Research Center, VIB Institute, Ghent, Belgium; Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium., Gevaert K; VIB-UGent Center for Medical Biotechnology, VIB Institute, Ghent, Belgium; Department of Biomolecular Medicine, Ghent University, Ghent, Belgium., Eyckerman S; VIB-UGent Center for Medical Biotechnology, VIB Institute, Ghent, Belgium; Department of Biomolecular Medicine, Ghent University, Ghent, Belgium. Electronic address: sven.eyckerman@vib-ugent.be., De Bosscher K; VIB-UGent Center for Medical Biotechnology, VIB Institute, Ghent, Belgium; Department of Biomolecular Medicine, Ghent University, Ghent, Belgium. Electronic address: karolien.debosscher@vib-ugent.be.

Publikováno v: Molecular & cellular proteomics : MCP [Mol Cell Proteomics] 2024 Mar; Vol. 23 (3), pp. 100741. Date of Electronic Publication: 2024 Feb 20.

Optimizing the implementation of a forest fuel break network.

Autor: Ager AA; USDA Forest Service, Rocky Mountain Research Station, Missoula Fire Sciences Lab, Missoula, Montana, United States of America., Day MA; USDA Forest Service, Rocky Mountain Research Station, Missoula Fire Sciences Lab, Missoula, Montana, United States of America., Aparício BA; International Visiting Scholar, USDA Forest Service, Rocky Mountain Research Station, Missoula Fire Sciences Lab, Missoula, Montana, United States of America., Houtman R; USDA Forest Service, Rocky Mountain Research Station, Missoula Fire Sciences Lab, Missoula, Montana, United States of America.; Oregon State University, College of Forestry, Forest Ecosystems & Society, Corvallis, Oregon, United States of America., Stinchfield A; USDA Forest Service, Umatilla National Forest, Pendleton, Oregon, United States of America.

Publikováno v: PloS one [PLoS One] 2023 Dec 13; Vol. 18 (12), pp. e0295392. Date of Electronic Publication: 2023 Dec 13 (Print Publication: 2023).

The Hippocampal Response to Acute Corticosterone Elevation Is Altered in a Mouse Model for Angelman Syndrome.

Autor: Viho EMG; Department of Medicine, Division of Endocrinology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands.; Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands., Punt AM; Department of Clinical Genetics, Erasmus MC, 3015 GD Rotterdam, The Netherlands.; ENCORE Expertise Center for Neurodevelopmental Disorders, Erasmus MC, 3015 GD Rotterdam, The Netherlands., Distel B; Department of Clinical Genetics, Erasmus MC, 3015 GD Rotterdam, The Netherlands.; ENCORE Expertise Center for Neurodevelopmental Disorders, Erasmus MC, 3015 GD Rotterdam, The Netherlands., Houtman R; Precision Medicine Lab, 5349 AB Oss, The Netherlands., Kroon J; Department of Medicine, Division of Endocrinology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands.; Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands., Elgersma Y; Department of Clinical Genetics, Erasmus MC, 3015 GD Rotterdam, The Netherlands.; ENCORE Expertise Center for Neurodevelopmental Disorders, Erasmus MC, 3015 GD Rotterdam, The Netherlands., Meijer OC; Department of Medicine, Division of Endocrinology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands.; Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2022 Dec 24; Vol. 24 (1). Date of Electronic Publication: 2022 Dec 24.

A phospholipid mimetic targeting LRH-1 ameliorates colitis.

Autor: Mays SG; Department of Biochemistry, Emory University, Atlanta, GA, USA., D'Agostino EH; Department of Biochemistry, Emory University, Atlanta, GA, USA., Flynn AR; Department of Chemistry, Emory University, Atlanta, GA, USA., Huang X; Department of Molecular and Cell Biology, Baylor College of Medicine, Houston, TX, USA; Department of Pediatrics, Baylor College of Medicine and Texas Children's Hospital, Houston, TX, USA., Wang G; Department of Molecular and Cell Biology, Baylor College of Medicine, Houston, TX, USA; Department of Pediatrics, Baylor College of Medicine and Texas Children's Hospital, Houston, TX, USA., Liu X; Department of Biochemistry, Emory University, Atlanta, GA, USA., Millings EJ; Department of Biochemistry, Emory University, Atlanta, GA, USA; Department of Surgery, Emory University, Atlanta, GA, USA., Okafor CD; Department of Biochemistry, Emory University, Atlanta, GA, USA., Patel A; Department of Biochemistry, Emory University, Atlanta, GA, USA., Cato ML; Department of Biochemistry, Emory University, Atlanta, GA, USA., Cornelison JL; Department of Chemistry, Emory University, Atlanta, GA, USA., Melchers D; Precision Medicine Lab, Oss, the Netherlands., Houtman R; Precision Medicine Lab, Oss, the Netherlands., Moore DD; Department of Molecular and Cell Biology, Baylor College of Medicine, Houston, TX, USA; Department of Nutritional Sciences and Toxicology, University of California, Berkeley, Berkeley, CA, USA., Calvert JW; Department of Surgery, Emory University, Atlanta, GA, USA., Jui NT; Department of Chemistry, Emory University, Atlanta, GA, USA. Electronic address: nathan.jui@gmail.com., Ortlund EA; Department of Biochemistry, Emory University, Atlanta, GA, USA. Electronic address: eortlun@emory.edu.

Publikováno v: Cell chemical biology [Cell Chem Biol] 2022 Jul 21; Vol. 29 (7), pp. 1174-1186.e7. Date of Electronic Publication: 2022 Mar 21.