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Analysis of pulmonary vascular injury and repair during Pseudomonas aeruginosa infection-induced pneumonia and acute respiratory distress syndrome.

Autor: Lindsey AS; 1 Department of Physiology and Cell Biology, University of South Alabama, Alabama, USA.; 2 Department of Microbiology and Immunology, University of South Alabama, Alabama, USA.; 3 Center for Lung Biology, University of South Alabama, Alabama, USA., Sullivan LM; 1 Department of Physiology and Cell Biology, University of South Alabama, Alabama, USA.; 3 Center for Lung Biology, University of South Alabama, Alabama, USA., Housley NA; 2 Department of Microbiology and Immunology, University of South Alabama, Alabama, USA.; 3 Center for Lung Biology, University of South Alabama, Alabama, USA., Koloteva A; 3 Center for Lung Biology, University of South Alabama, Alabama, USA., King JA; 4 Department of Pathology and Translational Pathobiology, Louisiana State University Health, Louisiana, USA., Audia JP; 2 Department of Microbiology and Immunology, University of South Alabama, Alabama, USA.; 3 Center for Lung Biology, University of South Alabama, Alabama, USA., Alvarez DF; 1 Department of Physiology and Cell Biology, University of South Alabama, Alabama, USA.; 3 Center for Lung Biology, University of South Alabama, Alabama, USA.; 5 University of South Alabama College of Medicine, Alabama, USA.

Publikováno v: Pulmonary circulation [Pulm Circ] 2019 Jan-Mar; Vol. 9 (1), pp. 2045894019826941.

Rickettsia prowazekii methionine aminopeptidase as a promising target for the development of antibacterial agents.

Autor: Helgren TR; Department of Chemistry and Biochemistry, Northern Illinois University, 1425 W. Lincoln Hwy, DeKalb, IL 60115, USA., Chen C; Department of Chemistry and Biochemistry, Northern Illinois University, 1425 W. Lincoln Hwy, DeKalb, IL 60115, USA., Wangtrakuldee P; Department of Chemistry and Biochemistry, Northern Illinois University, 1425 W. Lincoln Hwy, DeKalb, IL 60115, USA., Edwards TE; Beryllium Discovery Corp., 7869 NE Day Road West, Bainbridge Island, WA 98110, USA; Seattle Structural Genomics Center for Infectious Disease (SSGCID), Seattle, WA, USA., Staker BL; Center for Infectious Disease Research, Formerly Seattle Biomedical Research Institute, 307 Westlake Avenue N., Seattle, WA 98109, USA; Seattle Structural Genomics Center for Infectious Disease (SSGCID), Seattle, WA, USA., Abendroth J; Beryllium Discovery Corp., 7869 NE Day Road West, Bainbridge Island, WA 98110, USA; Seattle Structural Genomics Center for Infectious Disease (SSGCID), Seattle, WA, USA., Sankaran B; Molecular Biophysics and Integrated Bioimaging, Berkeley Center for Structural Biology, Ernest Orlando Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA., Housley NA; Department of Microbiology and Immunology and The Center for Lung Biology, University of South Alabama College of Medicine, Laboratory of Infectious Diseases, 307 North University Blvd, Mobile, AL 36688, USA., Myler PJ; Center for Infectious Disease Research, Formerly Seattle Biomedical Research Institute, 307 Westlake Avenue N., Seattle, WA 98109, USA; Seattle Structural Genomics Center for Infectious Disease (SSGCID), Seattle, WA, USA; Department of Global Health and Department of Biomedical Informatics and Medical Education, University of Washington, Seattle, WA 98195, USA., Audia JP; Department of Microbiology and Immunology and The Center for Lung Biology, University of South Alabama College of Medicine, Laboratory of Infectious Diseases, 307 North University Blvd, Mobile, AL 36688, USA., Horn JR; Department of Chemistry and Biochemistry, Northern Illinois University, 1425 W. Lincoln Hwy, DeKalb, IL 60115, USA., Hagen TJ; Department of Chemistry and Biochemistry, Northern Illinois University, 1425 W. Lincoln Hwy, DeKalb, IL 60115, USA. Electronic address: thagen@niu.edu.

Publikováno v: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2017 Feb 01; Vol. 25 (3), pp. 813-824. Date of Electronic Publication: 2016 Nov 10.

The Rickettsia prowazekii ExoU homologue possesses phospholipase A1 (PLA1), PLA2, and lyso-PLA2 activities and can function in the absence of any eukaryotic cofactors in vitro.

Autor: Housley NA; Laboratory of Molecular Biology, Department of Microbiology and Immunology, University of South Alabama College of Medicine, Mobile, AL 36688, USA., Winkler HH, Audia JP

Publikováno v: Journal of bacteriology [J Bacteriol] 2011 Sep; Vol. 193 (18), pp. 4634-42. Date of Electronic Publication: 2011 Jul 15.