Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Houshun Zhu"'
Autor:
Can Li, Kelvin K.W. To, Anna J. X. Zhang, Andrew C.Y. Lee, Houshun Zhu, Winger W.N. Mak, Ivan F. N. Hung, Kwok-Yung Yuen
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/bad75cb0f4c446c4b44d295be721655a
Autor:
Can Li, Kelvin K. W. To, Anna J. X. Zhang, Andrew C. Y. Lee, Houshun Zhu, Winger W. N. Mak, Ivan F. N. Hung, Kwok-Yung Yuen
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Current influenza vaccines have relatively low effectiveness, especially against antigenically drifted strains, the effectiveness is even lower in the elderly and immunosuppressed individuals. We have previously shown in a randomized clinical trial t
Externí odkaz:
https://doaj.org/article/97857d21dda54d24a74f28ab741254b6
Autor:
Can Li, Chuangen Li, Anna J X Zhang, Kelvin K W To, Andrew C Y Lee, Houshun Zhu, Hazel W L Wu, Jasper F W Chan, Honglin Chen, Ivan F N Hung, Lanjuan Li, Kwok-Yung Yuen
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107966 (2014)
Human infection caused by the avian influenza A H7N9 virus has a case-fatality rate of over 30%. Systematic study of the pathogenesis of avian H7N9 isolate and effective therapeutic strategies are needed.BALB/c mice were inoculated intranasally with
Externí odkaz:
https://doaj.org/article/c89fcd25f6eb4dd8bea02058b565966c
Publikováno v:
Biomaterials Science. 8:2283-2288
Highly efficient tumor-targeted therapy remains a great challenge due to the complexity and heterogeneity of tumor tissues. Herein, we developed an in vivo two-step tumor-targeting strategy by combining metabolic lipid-engineering with a stain-promot
Autor:
Leonardi Gozali, Anna J. X. Zhang, Ivan Hung, Houshun Zhu, Chuangen Li, Hin Chu, Can Li, Andrew Chak-Yiu Lee, Kwok-Yung Yuen, Yanxia Chen, Kelvin K. W. To
Publikováno v:
The Journal of Infectious Diseases. 219:795-807
BACKGROUND Obesity is associated with increased severity of influenza infection. However, the underlying mechanism is largely unknown. METHODS We employed a mouse model with diet-induced obesity (DIO) to study the innate immune responses induced by i
Autor:
Hin Chu, Kwok-Yung Yuen, Houshun Zhu, Anna J. X. Zhang, Can Li, Winger W N Mak, Andrew Chak-Yiu Lee, Kelvin K. W. To
Publikováno v:
Journal of General Virology. 98:922-934
Most patients with avian influenza A H7N9 virus (H7N9) infection suffer from severe illness, accompanied by dysregulated cytokine/chemokine response, delayed viral clearance and impaired neutralizing antibody response. Here, we evaluated the role of
Autor:
Houshun Zhu, Kelvin K. W. To, Andrew Chak-Yiu Lee, Yanxia Chen, Can Li, Winger W N Mak, Anna J. X. Zhang, Kwok-Yung Yuen, Kin-Hang Kok, Hin Chu
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 10, Iss 6, Pp 1-16 (2019)
Cell Death and Disease, Vol 10, Iss 6, Pp 1-16 (2019)
We previously demonstrated that avian influenza A H7N9 virus preferentially infected CD14+ monocyte in human peripheral blood mononuclear cells (PBMCs), which led to apoptosis. To better understand H7N9 pathogenesis in relation to monocyte cell death
Autor:
Houshun Zhu, Yetta Y. Chen, Anna J. X. Zhang, Rui-Qi Zhang, Yim-Fong Fung, Kwok-Yung Yuen, Joy-Yan Lam, Kwok-Hung Chan, Wai-Fong Fung, Rosana W.S. Poon, Winger W N Mak, Ivan Hung, Honglin Chen, Andrew Chak-Yiu Lee, Sidney Tam, Can Li, Kelvin K. W. To
Publikováno v:
Emerging Microbes & Infections
The 2017 Hong Kong influenza A(H3N2) summer season was unexpectedly severe. However, antigenic characterization of the 2017 circulating A(H3N2) viruses using ferret antisera did not show significant antigenic drift. We analyzed the hemagglutinin amin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75a478a046fe08554fe5ccab240ebc8b
Autor:
Zheng Zhu, Feifei Yin, Kah-Meng Tee, Kwok-Hung Chan, Vincent Kwok-Man Poon, Chris Chung-Sing Chan, Houshun Zhu, Rex Au-Yeung, Dong-Yan Jin, Cyril C. Y. Yip, Kenn Ka-Heng Chik, Winger Wing-Nga Mak, Kwok-Yung Yuen, Anna Jinxia Zhang, Kin-Hang Kok, Jasper Fuk-Woo Chan, Jessica Oi-Ling Tsang, Jian-Piao Cai
Publikováno v:
EBioMedicine
Background Disseminated or fatal Zika virus (ZIKV) infections were reported in immunosuppressed patients. Existing interferon-signaling/receptor-deficient mouse models may not be suitable for evaluating treatment effects of recombinant interferons. M