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Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract To determine the synergistic effect and mechanism of AO/854, a new Bloom syndrome protein (BLM) helicase inhibitor, and cisplatin (CDDP), a DNA-crosslinking agent, cell viability assays, neutral comet assays, and Western blotting (WB) were p
Externí odkaz:
https://doaj.org/article/649e30295b39469a9b08f4a31ba83107
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background Prostate cancer (PCa) is a leading malignancy among men globally, with rising incidence rates emphasizing the critical need for better detection and therapeutic approaches. The roles of HSP90AB1 and PARP1 in prostate cancer cells
Externí odkaz:
https://doaj.org/article/df19228ae1aa4ae3a4eac0a5fd55d607
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Prostate cancer (PCa) ranks as the second most prevalent cancer among males globally. However, the exact mechanisms underlying its progression remain inadequately elucidated. The present study sought to investigate the role and underlying mo
Externí odkaz:
https://doaj.org/article/4afdcb6e6dc84046a651890c153abe0e
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract In recent years, there has been an increase in the incidence and mortality rates of prostate cancer (PCa). However, the specific molecular mechanisms underlying its occurrence and development remain unclear, necessitating the identification
Externí odkaz:
https://doaj.org/article/ab3241d08bed4623b7fed2a625f9c1e7
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
IntroductionAcetyl-Coenzyme A Acyltransferase-1 (ACAA1) is a peroxisomal acyltransferase involved in fatty acid metabolism. Current evidence does not precisely reveal the effect of the ACAA1 gene on pig growth performance.MethodsThe present study ass
Externí odkaz:
https://doaj.org/article/cb14309d4f914d5c9c8e4bdb2a9eae24
Autor:
Jiajin Huang, Yong Ruan, Meimei Xiao, Lingang Dai, Chuanmei Jiang, Jifeng Li, Jiali Xu, Xiang Chen, Houqiang Xu
Publikováno v:
Frontiers in Veterinary Science, Vol 11 (2024)
The newborn ovary homeobox gene (NOBOX) regulates ovarian and early oocyte development, and thus plays an essential role in reproduction. In this study, the mRNA expression level and single nucleotide polymorphism (SNP) of NOBOX in various tissues of
Externí odkaz:
https://doaj.org/article/2b165df58f1f40278661042db56518cd
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-19 (2023)
Abstract Background Prostate cancer (PCa) is a prevalent malignant disease affecting a significant number of males globally. Elevated expression of the Bloom’s syndrome protein (BLM) helicase has emerged as a promising cancer biomarker, being assoc
Externí odkaz:
https://doaj.org/article/f975ca0de3ae4fafafdcf03434f0de1f
Publikováno v:
Epigenetics, Vol 17, Iss 12, Pp 1800-1819 (2022)
Intramuscular fat development is regulated by a series of complicated processes, with non-coding RNA (ncRNA) such as microRNA (miRNA) having a critical role during intramuscular preadipocyte proliferation and differentiation in pigs. In the present s
Externí odkaz:
https://doaj.org/article/39ece6405f0643b49597577947df9a05
Autor:
Jingran Liu, Houqiang Xia, Yang Gao, Dongyu Pan, Jian Sun, Ming Liu, Zhonghou Tang, Zongyun Li
Publikováno v:
Frontiers in Plant Science, Vol 13 (2022)
In order to explore the effect of potassium (K) deficiency on nitrogen (N) metabolism in sweet potato (Ipomoea batatas L.), a hydroponic experiment was conducted with two genotypes (Xushu 32, low-K-tolerant; Ningzishu 1, low-K-sensitive) under two K
Externí odkaz:
https://doaj.org/article/c1eab34a9b004e57bb179c33b827224a