Zobrazeno 1 - 10
of 179
pro vyhledávání: '"Houjie Liang"'
Autor:
Yan Dong, Yanrong Chen, Yijie Wang, Xiang Zhao, Ruiyang Zi, Jie Hao, Qiong Ding, Haoran Jiang, Xuesong Wang, Fanghao Lu, Houjie Liang, Zhihao Wei, Jianjun Li
Publikováno v:
Genes and Diseases, Vol 11, Iss 6, Pp 101330- (2024)
Resistance to sorafenib, an effective first-line treatment for advanced hepatocellular carcinoma (HCC), greatly compromised the prognosis of patients. The extracellular matrix is one of the most abundant components of the tumor microenvironment. Beyo
Externí odkaz:
https://doaj.org/article/ff565c9ac4d347829ab0fe804f2de763
Autor:
Jiujie Cui, Qihan Fu, Xiaobing Chen, Yanling Wang, Qi Li, Feng Wang, Zhihua Li, Guanghai Dai, Yusheng Wang, Hongmei Zhang, Houjie Liang, Jun Zhou, Liu Yang, Fenghua Wang, Leizhen Zheng, Xiaofeng Chen, Ping Gong, Jiang Liu, Ying Yuan, Lin Wang, Yuejuan Cheng, Jun Zhang, Yuhong Zhou, Weijian Guo, Xianbao Zhan, Zhengyun Zou, Da Li, Shan Zeng, Enxiao Li, Zhiwei Li, Zan Teng, Dan Cao, Jie Kan, Jianping Xiong, Ming Quan, Jiayu Yao, Haiyan Yang, Liwei Wang
Publikováno v:
Journal of Pancreatology, Vol 7, Iss 1, Pp 1-9 (2024)
Objective:. Real-world diagnostic and treatment data for pancreatic cancer in China are lacking. As such, the present study investigated the clinical characteristics, diagnosis, and treatment of advanced pancreatic cancer (including locally advanced
Externí odkaz:
https://doaj.org/article/2e0a1c4b680346ddb97288531b46b3bf
Autor:
Chi Zhang, Yue Zhang, Yan Dong, Ruiyang Zi, Yijie Wang, Yanrong Chen, Chengxiang Liu, Junyi Wang, Xuesong Wang, Jianjun Li, Houjie Liang, Juanjuan Ou
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-15 (2024)
Abstract Liver metastasis is the major reason for most of colorectal cancer (CRC) related deaths. Accumulating evidence indicates that CRC patients with non-alcoholic fatty liver disease (NAFLD) are at a greater risk of developing liver metastasis. W
Externí odkaz:
https://doaj.org/article/e06053e593ab4976a59c3eda28e6822d
Autor:
Jiujie Cui, Feng Jiao, Qi Li, Zheng Wang, Deliang Fu, Jun Liang, Houjie Liang, Tingyi Xia, Tao Zhang, Yang Zhang, Guanghai Dai, Zhihong Zhang, Jian Wang, Yongrui Bai, Yuxian Bai, Feng Bi, Donghui Chen, Dan Cao, Jie Chen, Weijia Fang, Yong Gao, Jianwei Guo, Jihui Hao, Haiqing Hua, Xinyu Huang, Wenchao Liu, Xiufeng Liu, Da Li, Ji Li, Enxiao Li, Zhiwei Li, Hongming Pan, Lin Shen, Yongwei Sun, Min Tao, Chengfeng Wang, Fenghua Wang, Jianping Xiong, Taiping Zhang, Xuebin Zhang, Xianbao Zhan, Leizhen Zheng, Gang Ren, Tingting Zhang, Jun Zhou, Qingyong Ma, Shukui Qin, Chunyi Hao, Liwei Wang
Publikováno v:
Journal of the National Cancer Center, Vol 2, Iss 4, Pp 205-215 (2022)
Pancreatic cancer is one of the leading causes of cancer-related mortality in both developed and developing countries. The incidence of pancreatic cancer in China accounts for about a quater of the global incidence, and the epidemiological characteri
Externí odkaz:
https://doaj.org/article/76c886fc6e8f481db6ee7626b49e89d7
Autor:
Zhe Wang, Jianfang Chen, Fengjun Sun, Xiang Zhao, Yan Dong, Songtao Yu, Jianjun Li, Houjie Liang
Publikováno v:
Cell & Bioscience, Vol 12, Iss 1, Pp 1-21 (2022)
Abstract Background Colorectal liver metastases (CRLM) continue to have a low survival rate. The number of CRLM regulators and clinical indicators remains limited. Long non-coding RNAs (lncRNAs) are a new master regulator of cell invasion and metasta
Externí odkaz:
https://doaj.org/article/baca99ceb8d640b1b7ef31a52aa773d8
Autor:
Jie Zhou, Zengjie Lei, Jianfang Chen, Shengbo Liao, Yanrong Chen, Chengxiang Liu, Shuo Huang, Liuli Li, Yan Zhang, Pei Wang, Yinghui Huang, Jianjun Li, Houjie Liang
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 5, Pp n/a-n/a (2023)
Abstract Background During the tumourigenesis and development of colorectal cancer (CRC), the inactivation of tumour suppressor genes is closely involved, although detailed molecular mechanisms remain elusive. Accumulating studies, including ours, ha
Externí odkaz:
https://doaj.org/article/00556e9142d04deaaed07c5d2962aaf9
Autor:
Guoliang Shao, Yuxian Bai, Xianglin Yuan, Xiaomin Chen, Shanzhi Gu, Kangsheng Gu, Chunhong Hu, Houjie Liang, Yabing Guo, Jufeng Wang, Chia-Jui Yen, Victor Ho-Fun Lee, Chunxiao Wang, Ryan C. Widau, Wanli Zhang, Junjun Liu, Qiang Zhang, Shukui Qin
Publikováno v:
EClinicalMedicine, Vol 54, Iss , Pp 101679- (2022)
Summary: Background: In the global REACH-2 study, ramucirumab significantly improved overall survival (OS) compared with placebo in patients with advanced hepatocellular carcinoma (HCC) and elevated alpha-fetoprotein (AFP). REACH-2 China study aimed
Externí odkaz:
https://doaj.org/article/e806fe3c322947ce9fe7c571dbf725cc
Autor:
Xiaoxing Wu, Zhaoxia Li, Hongyu Zhang, Fang He, Min Qiao, Huaxiu Luo, Jing Zhang, Meng Zhang, Yukun Mao, William Wagstaff, Yongtao Zhang, Changchun Niu, Xia Zhao, Hao Wang, Linjuan Huang, Deyao Shi, Qing Liu, Na Ni, Kai Fu, Rex C. Haydon, Russell R. Reid, Hue H. Luu, Tong-Chuan He, Ziwei Wang, Houjie Liang, Bing-Qiang Zhang, Ning Wang
Publikováno v:
Genes and Diseases, Vol 10, Iss 2, Pp 618-619 (2023)
Externí odkaz:
https://doaj.org/article/b718347dedff45748a508c813889ce68
Autor:
Xiaoxing Wu, Zhaoxia Li, Hongyu Zhang, Fang He, Min Qiao, Huaxiu Luo, Jing Zhang, Meng Zhang, Yukun Mao, William Wagstaff, Yongtao Zhang, Changchun Niu, Xia Zhao, Hao Wang, Linjuan Huang, Deyao Shi, Qing Liu, Na Ni, Kai Fu, Rex C. Haydon, Russell R. Reid, Hue H. Luu, Tong-Chuan He, Ziwei Wang, Houjie Liang, Bing-Qiang Zhang, Ning Wang
Publikováno v:
Genes and Diseases, Vol 8, Iss 6, Pp 814-826 (2021)
Intestinal cancers are developed from intestinal epithelial stem cells (ISCs) in intestinal crypts through a multi-step process involved in genetic mutations of oncogenes and tumor suppressor genes. ISCs play a key role in maintaining the homeostasis
Externí odkaz:
https://doaj.org/article/b62ec6831db14330a53c2808e959d5f7
Autor:
Yan Gu, Yanrong Chen, Lai Wei, Shuang Wu, Kaicheng Shen, Chengxiang Liu, Yan Dong, Yang Zhao, Yue Zhang, Chi Zhang, Wenling Zheng, Jiangyi He, Yunlong Wang, Yifei Li, Xiaoxin Zhao, Hongwei Wang, Jun Tan, Liting Wang, Qi Zhou, Ganfeng Xie, Houjie Liang, Juanjuan Ou
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
This study reveals an unrecognized role of ABHD5 in regulating colon cancer stemness via controlling YAP methylation and nuclear localization, further explaining the molecular mechanism through which ABHD5 functions as a tumour suppressor gene in col
Externí odkaz:
https://doaj.org/article/33c740cbfc424f82b51a157bae061d41