Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Houda Cohen"'
Autor:
Addeli Bez Batti Angulski, Houda Cohen, Mihee Kim, Dongwoo Hahn, Nicholas Van Zee, Timothy P. Lodge, Marc A. Hillmyer, Benjamin J. Hackel, Frank S. Bates, Joseph M. Metzger
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 28, Iss , Pp 162-176 (2023)
First-in-class membrane stabilizer Poloxamer 188 (P188) has been shown to confer membrane protection in an extensive range of clinical conditions; however, elements of the systemic distribution and localization of P188 at the organ, tissue, and muscl
Externí odkaz:
https://doaj.org/article/3a1e938556b44502a67ac72b87b2ecd7
Autor:
Addeli Bez Batti Angulski, Nora Hosny, Houda Cohen, Ashley A. Martin, Dongwoo Hahn, Jack Bauer, Joseph M. Metzger
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Duchenne muscular dystrophy (DMD) is a severe, progressive, and ultimately fatal disease of skeletal muscle wasting, respiratory insufficiency, and cardiomyopathy. The identification of the dystrophin gene as central to DMD pathogenesis has led to th
Externí odkaz:
https://doaj.org/article/2b3aa11e116f4bf28707b71e01775f87
Autor:
Ashley A. Martin, Brian R. Thompson, Dongwoo Hahn, Addeli Bez Batti Angulski, Nora Hosny, Houda Cohen, Joseph M. Metzger
Publikováno v:
International journal of molecular sciences. 23(24)
The cardiac sarcomere is a triumph of biological evolution wherein myriad contractile and regulatory proteins assemble into a quasi-crystalline lattice to serve as the central point upon which cardiac muscle contraction occurs. This review focuses on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c7c2e9d03b8c50c84de52e289de9e71
https://pubmed.ncbi.nlm.nih.gov/36555864
https://pubmed.ncbi.nlm.nih.gov/36555864
Publikováno v:
Circulation Research. 131
Duchenne muscular dystrophy (DMD) is a fatal X-linked recessive disease caused by a mutation in the dystrophin gene resulting in a complete loss of dystrophin from the striated muscle. This leads to the disruption of the dystrophin-associated glycopr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef0b47cdd014771a7d90f3e90950926f
https://doi.org/10.1161/res.131.suppl_1.p2038
https://doi.org/10.1161/res.131.suppl_1.p2038
Autor:
Melissa K. Gardner, Hluechy X. Vang, Cody R. Hou, Rebecca R. Goldblum, Brian R. Thompson, Houda Cohen, Mark McClellan, Joseph M. Metzger, Kyle White
In the failing heart, the cardiac myocyte microtubule network is remodeled, which increases cellular stiffness and disrupts contractility, contributing to heart failure and death. However, the origins of this deleterious cytoskeletal reorganization a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9fe41126df468c15abb0b160b244d66
https://doi.org/10.1101/2020.06.30.174532
https://doi.org/10.1101/2020.06.30.174532
Publikováno v:
Journal of Clinical Medicine, Vol 9, Iss 2, p 520 (2020)
Journal of Clinical Medicine
Journal of Clinical Medicine
Duchenne muscular dystrophy (DMD) is an X-linked recessive disease resulting in the loss of dystrophin, a key cytoskeletal protein in the dystrophin-glycoprotein complex. Dystrophin connects the extracellular matrix with the cytoskeleton and stabiliz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39d0dc5143f4c498304096fc04c078a6
https://www.mdpi.com/2077-0383/9/2/520
https://www.mdpi.com/2077-0383/9/2/520
Autor:
Joseph M. Metzger, Kyle White, Hluechy X. Vang, Samuel J. Gonzalez, Todd W. Markowski, LeeAnn Higgins, Rebecca R. Goldblum, Houda Cohen, Mark McClellan, Tzu Yi Yang, Brian R. Thompson, Melissa K. Gardner
Publikováno v:
Dev Cell
In the failing heart, the cardiac myocyte microtubule network is remodeled, which contributes to cellular contractile failure and patient death. However, the origins of this deleterious cytoskeletal reorganization are unknown. We now find that oxidat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b6287bc0ea5b0135edd79e22c8c7132
https://doi.org/10.1016/j.devcel.2021.07.004
https://doi.org/10.1016/j.devcel.2021.07.004
Publikováno v:
Methods in Molecular Biology ISBN: 9781493990290
Heart failure is the leading cause of combined morbidity and mortality in the USA with 50% of cases being diastolic heart failure. Diastolic heart failure results from poor myocardial relaxation and inadequate filling of the left ventricular chamber
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a6a62ee395671d39b2a5b900ca49811
https://doi.org/10.1007/978-1-4939-9030-6_12
https://doi.org/10.1007/978-1-4939-9030-6_12