Zobrazeno 1 - 10
of 381
pro vyhledávání: '"Hou-wen Lin"'
Autor:
Haixia Zang, Yijia Cheng, Mengjia Li, Lin Zhou, Li-Li Hong, Hai Deng, Hou-Wen Lin, Yongjun Zhou
Publikováno v:
Microbial Cell Factories, Vol 23, Iss 1, Pp 1-11 (2024)
Abstract Background Natural tetramates are a family of hybrid polyketides bearing tetramic acid (pyrrolidine-2,4-dione) moiety exhibiting a broad range of bioactivities. Biosynthesis of tetramates in microorganisms is normally directed by hybrid poly
Externí odkaz:
https://doaj.org/article/3c8eb3ebe787474681008fcc9b16838c
Autor:
Li Guan, Ya-Hui Liao, Meng-Xue Cao, Li-Yun Liu, Hai-Tao Xue, Hong-Rui Zhu, Chang-Hao Bian, Fan Yang, Hou-Wen Lin, Hong-Ze Liao, Fan Sun
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Multidrug resistance is a substantial obstacle in treating non-small cell lung cancer (NSCLC) with therapies like cisplatin (DDP)-based adjuvant chemotherapy and EGFR-tyrosine kinase inhibitors (TKIs). Aaptamine-7 (AP-7), a benzonaphthyridine alkaloi
Externí odkaz:
https://doaj.org/article/27cd28fab42f4256b0cbf54f438f41ce
Autor:
Mang-Mang Pan, Chi Zhang, Long Shen, Jing-Jing Sha, Hui Shen, Yi-Dan Yan, Jia Wang, Xin Wang, Hou-Wen Lin, Zhi-Chun Gu
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-12 (2023)
Abstract Background Atrial fibrillation (AF) is a common arrhythmia that requires anticoagulation therapy to prevent stroke. However, there is still a significant under-/over-treatment in stroke prevention for patients with AF. The adherence and the
Externí odkaz:
https://doaj.org/article/7a8880725bcd46129e5d4d7af1dfcbdc
Autor:
Ming Yang, Wanlu Li, Lin Zhou, Xiao Lin, Wenyu Zhang, Yaoyao Shen, Hai Deng, Hou-wen Lin, Yongjun Zhou
Publikováno v:
Synthetic and Systems Biotechnology, Vol 8, Iss 3, Pp 349-356 (2023)
The bacterial trialkyl-substituted aromatic polyketides are structurally featured with the unusual aromatic core in the middle of polyketide chain such as TM-123 (1), veramycin A (2), NFAT-133 (3) and benwamycin I (4), which were discovered from Stre
Externí odkaz:
https://doaj.org/article/722f28b8f482441d9ce910a91ba67a3e
Autor:
Xin Peng, Yingying Wang, Shaolu Zhang, Zhennan Tao, Yuxiang Dai, Francois X. Claret, Moshe Elkabets, Hou-Wen Lin, Zhe-Sheng Chen, Dexin Kong
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-4 (2023)
Externí odkaz:
https://doaj.org/article/97a884f58d4847c9aeb7134160e38a14
Publikováno v:
Synthetic and Systems Biotechnology, Vol 7, Iss 3, Pp 880-886 (2022)
Piericidins are a large family of bacterial α-pyridone antibiotics with antitumor activities such as their anti-renal carcinoma activity exhibited recently in nude mice. The backbones of piericidins are derived from β, δ-diketo carboxylic acids, w
Externí odkaz:
https://doaj.org/article/16393221a3af4e78bcadd436cd0d1a1d
Autor:
Nan-Nan Shen MS, Eliana Ferroni MS, Claudio Barbiellini Amidei MS, Cristina Canova PhD, Viviana Peron MS, Jia-Liang Wang MS, Hou-Wen Lin PhD, Zhi-Chun Gu MS
Publikováno v:
Clinical and Applied Thrombosis/Hemostasis, Vol 29 (2023)
Introduction Off-label, under-, and overdosed direct oral anticoagulants (DOACs) are commonly prescribed to patients with atrial fibrillation (AF), but real-world evidence on their effectiveness and safety is limited. Methods MEDLINE, Embase, and Coc
Externí odkaz:
https://doaj.org/article/1cd70e1b24ce41d29fda83ffded08d9e
Publikováno v:
Communications Chemistry, Vol 5, Iss 1, Pp 1-8 (2022)
Aryldifluoromethyl aryl ethers (ArCF2OAr’) are powerful structural motifs to improve druggability, however, their targeted synthesis remains challenging. Here, the authors report the efficient synthesis of ArCF2OAr’ motifs via nickel-catalyzed ar
Externí odkaz:
https://doaj.org/article/bd16d8e3410648e98d32782186775cae
Autor:
Yi–Dan Yan MSc, Ze Yu MD, Lan-Ping Ding MSc, Min Zhou MD, Chi Zhang MSc, Mang-Mang Pan MSc, Jin-Yuan Zhang MD, Ze-Yuan Wang MD, Fei Gao MD, Hang-Yu Li MD, Guang-Yong Zhang PhD, Hou-Wen Lin PhD, Ming-Gang Wang PhD, Zhi–Chun Gu MSc
Publikováno v:
Clinical and Applied Thrombosis/Hemostasis, Vol 29 (2023)
Background The accuracy of current prediction tools for venous thromboembolism (VTE) events following hernia surgery remains insufficient for individualized patient management strategies. To address this issue, we have developed a machine learning (M
Externí odkaz:
https://doaj.org/article/25b8da6c01ff4b6c8c1b69baf1945a94
Autor:
Jia Wang, Yang-Xi Liu, Yi-Dan Yan, Li Liu, Chi Zhang, Mang-Mang Pan, Hou-Wen Lin, Zhi-Chun Gu
Publikováno v:
Journal of Interventional Cardiology, Vol 2023 (2023)
Background. Venous thromboembolism (VTE) is a common cardiovascular disease that seriously threatens human lives. Anticoagulant therapy is considered to be the cornerstone of VTE treatment. An increasing number of studies has been updated in the VTE
Externí odkaz:
https://doaj.org/article/32aa6c9b536940ab97d6add3b54e439d