Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Hou-Ying Qin"'
Publikováno v:
Oxidative Medicine and Cellular Longevity, Vol 2022 (2022)
Background. S100A4 is a member of the S100 calcium-binding protein family and is increased in patients with chronic obstructive pulmonary disease (COPD). Sphingosine-1-phosphate (S1P) is a naturally occurring bioactive sphingolipid, which regulates t
Publikováno v:
Toxicology letters. 240(1)
Early pulmonary inflammation and epithelial-mesenchymal transition (EMT) play important roles during lung fibrosis. Increasing evidence demonstrates that calcitriol, the active form of vitamin D3, has anti-inflammatory activities. The aim of this stu
Phenylbutyric acid inhibits epithelial-mesenchymal transition during bleomycin-induced lung fibrosis
Publikováno v:
Toxicology letters. 232(1)
A recent report showed that unfolded protein response (UPR) signaling was activated during bleomycin (BLM)-induced pulmonary fibrosis. Phenylbutyric acid (PBA) is an endoplasmic reticulum (ER) chemical chaperone that inhibits the UPR signaling. The p
Autor:
Hui Zhao, Qing-Qing Wu, Lin-Feng Cao, Hou-Ying Qing, Cheng Zhang, Yuan-Hua Chen, Hua Wang, Rong-Ru Liu, De-Xiang Xu
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97266 (2014)
Several reports indicate that melatonin alleviates bleomycin (BLM)-induced pulmonary fibrosis in rodent animals. Nevertheless, the exact mechanism remains obscure. The present study investigated the effects of melatonin on endoplasmic reticulum (ER)
Externí odkaz:
https://doaj.org/article/d47d54a14bd84af193a5e059e070cac3