Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Hou-Xiang Lu"'
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
The development of conjugate boryl addition to α,β-unsaturated amide has been hampered by the intrinsic low electrophilicity of the amide group. Here the authors show a catalytic asymmetric synthesis of enantioenriched tertiary boronic esters throu
Externí odkaz:
https://doaj.org/article/79062422f6d14c12871cc6a57055e2f7
Autor:
Hui-Qi Ni, Ilia Kevlishvili, Pranali G. Bedekar, Joyann S. Barber, Shouliang Yang, Michelle Tran-Dubé, Andrew M. Romine, Hou-Xiang Lu, Indrawan J. McAlpine, Peng Liu, Keary M. Engle
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
Dihydrobenzofurans and indolines are common substructures in medicines and natural products. Herein, the authors report a palladium-catalyzed [3 + 2] (hetero)annulation proceeding in an anti-selective fashion and enabling direct access to these valua
Externí odkaz:
https://doaj.org/article/945084f36cfa4b7a9ef932ab16789629
Publikováno v:
Accounts of Chemical Research. 56:308-321
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1befdda8c10b2c2ad3825b886f6d479c
https://doi.org/10.1021/acs.accounts.2c00713
https://doi.org/10.1021/acs.accounts.2c00713
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
Chiral tertiary boronic esters are important precursors to bioactive compounds and versatile synthetic intermediates to molecules containing quaternary stereocenters. The development of conjugate boryl addition to α,β-unsaturated amide has been ham
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adb0eb6c71c2a87ac3da1858f3c1e708
https://doi.org/10.1038/s41467-021-24012-z
https://doi.org/10.1038/s41467-021-24012-z
Autor:
Hou-Xiang Lu, Michelle Tran-Dubé, Indrawan James Mcalpine, Ilia Kevlishvili, Shouliang Yang, Pranali Bedekar, Joyann S. Barber, Hui-Qi Ni, Peng Liu, Keary M. Engle
2,3-Dihydrobenzofurans and indolines are common substructures in medicines and natural products. Herein, we describe a method that enables direct access to these core structures from non-conjugated alkenyl amides and ortho-iodoanilines/phenols. Under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28ea62d317fd37189abb550527d7235d
https://doi.org/10.26434/chemrxiv.12510038
https://doi.org/10.26434/chemrxiv.12510038
Autor:
John R. Coombs, Yang Gao, Matthew J. Goldfogel, Hou-Xiang Lu, Jiahao Chen, Xiaohan Li, Zhen Liu, Keary M. Engle
Publikováno v:
Angew Chem Int Ed Engl
We report the development of palladium(0)-catalyzed syn-selective 1,2-carboboration and -silylation reactions of alkenes containing cleavable directing groups. With B(2)pin(2) or PhMe(2)Si–Bpin as nucleophiles and aryl/alkenyl triflates as electrop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71146564a3f33e22e3bc46213bf116e7
https://pubmed.ncbi.nlm.nih.gov/31538388
https://pubmed.ncbi.nlm.nih.gov/31538388
Publikováno v:
Journal of the American Chemical Society. 141(11)
The control of chemo-, regio-, diastereo-, and enantioselectivity is a central theme in organic synthesis. The capability to obtain the full set of stereoisomers of a molecule would significantly enhance the efficiency for the synthesis of natural pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cedabd44dbaadc6ba586ccd933ab7e75
https://pubmed.ncbi.nlm.nih.gov/30807127
https://pubmed.ncbi.nlm.nih.gov/30807127