Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Hou-Bing Zhang"'
Autor:
Cheng-Tao Jiang, Kai-Ge Chen, An Liu, Hua Huang, Ya-Nan Fan, Dong-Kun Zhao, Qian-Ni Ye, Hou-Bing Zhang, Cong-Fei Xu, Song Shen, Meng-Hua Xiong, Jin-Zhi Du, Xian-Zhu Yang, Jun Wang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Current strategies to boost anti-tumor immune response include the use of immune checkpoint inhibitors and bispecific T cell-engaging antibodies. Here the authors describe a versatile antibody immobilization nanoplatform that can be used to deliver d
Externí odkaz:
https://doaj.org/article/df1fd3f94ada4483a1c1ec207bb754dd
Publikováno v:
Journal of Controlled Release. 324:47-54
Polymeric micelles hold great potential for anticancer drug delivery. Sufficient integrity of polymeric micelles after intravenous injection is critical for successful drug delivery to solid tumors, but accurate measurement of the in vivo micellar in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b935dee462793bc038c239174e3d474
https://doi.org/10.1016/j.jconrel.2020.04.046
https://doi.org/10.1016/j.jconrel.2020.04.046
Publikováno v:
Biomaterials Science. 7:4698-4707
Rheumatoid arthritis (RA) is a systemic autoimmune disease that can cause irreversible joint deformity. There is still no cure for RA, and current therapeutics, including methotrexate and adalimumab, cause serious off-target effects and systemic immu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2ff5d71911ea441dd7ee557cea379af
https://doi.org/10.1039/c9bm01025d
https://doi.org/10.1039/c9bm01025d
Autor:
Song Shen, Cheng-Tao Jiang, Hua Huang, Jin-Zhi Du, Meng-Hua Xiong, Qian-Ni Ye, Ya-Nan Fan, Dong-Kun Zhao, Jun Wang, Kai-Ge Chen, Cong-Fei Xu, Xianzhu Yang, An Liu, Hou-Bing Zhang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications
Nature Communications
Modulating effector immune cells via monoclonal antibodies (mAbs) and facilitating the co-engagement of T cells and tumor cells via chimeric antigen receptor- T cells or bispecific T cell-engaging antibodies are two typical cancer immunotherapy appro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6973eea5b0eb58d3ea6b023366288151
https://doi.org/10.1038/s41467-021-21497-6
https://doi.org/10.1038/s41467-021-21497-6
Autor:
Zhuzhong Cheng, Bin Song, Danyang Li, Ye Xu, Hou-Bing Zhang, Li Yang, Hua Ai, Chunchao Xia, Changqiang Wu, Bingbing Lin, Qiyong Gong
Publikováno v:
Journal of materials chemistry. B. 3(8)
T 1 contrast agents based on Mn(II) were conjugated on amphiphilic dextran micelles via click chemistry. The obtained paramagnetic nanomicelle contrast agent has a higher T1 relaxivity (13.3 Mn mmol−1 s−1) and better sensitivity than those of fre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83164f6d781dcac97973bb94755419db
https://pubmed.ncbi.nlm.nih.gov/32429604
https://pubmed.ncbi.nlm.nih.gov/32429604
Autor:
Wei Jiang, Zhi-Ting Cao, Xianzhu Yang, Yue Zhang, Jun Wang, Ji-Long Wang, Meng-Hua Xiong, Yucai Wang, Hou-Bing Zhang, Li-Qin Gan
Publikováno v:
ACS nano. 14(3)
Polymeric nanoparticles (NPs) are an important category of drug delivery systems, and their in vivo fate is closely associated with delivery efficacy. Analysis of the protein corona on the surface ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f38c11756d0cf20c5892c577da13ae9
https://pubmed.ncbi.nlm.nih.gov/32053346
https://pubmed.ncbi.nlm.nih.gov/32053346
Autor:
Xuechang Zhou, Yucai Wang, Jinbin Yang, Guoqing Zhang, Yangyang Zhao, Li Wang, Zhenhui Hou, Hou-Bing Zhang, Xianzhu Yang, Ji-Long Wang, Jun Wang, Wei Jiang, Zhiwei He, Ying-Li Luo, Fang Huang, Lifeng Yan, Jing Liu
Publikováno v:
Nano Research. 11:5716-5734
Hierarchical targeting strategy can combat the sequential drug delivery barriers by changing their properties with response to tumor stimuli. Among these strategies, much less attention has been paid to address the issues of rapid tumor clearance and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e877d9c715b4a8069e693f8fb447bb8
https://doi.org/10.1007/s12274-017-1925-4
https://doi.org/10.1007/s12274-017-1925-4
Autor:
Song Shen, Ying-Li Luo, Qian Chen, Zhen Gu, Li Wang, Hou-Bing Zhang, Jun Wang, Ya-Nan Fan, Min Li
Publikováno v:
Biomaterials Science. 6:3009-3018
Message RNA-based vaccines with prominent advantages such as facile production, no requirement for nuclear entry and high safety without the need for integration into host genome have been shown to be potent activators of the cytotoxic immune system.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e71a90adb8e77b2808da348c48947e7b
https://doi.org/10.1039/c8bm00908b
https://doi.org/10.1039/c8bm00908b
Autor:
Hou-Bing Zhang, Li Yang, Jiang Zhu, Bingbing Lin, Hua Ai, Danyang Li, Zhuzhong Chen, Xiao-Ming Zhang, Changqiang Wu
Publikováno v:
RSC Advances. 7:54603-54609
A novel rigid Mn2+ complex (MnL) with pyridine and pyrrolidine rings was designed and synthesized. The complex was further modified with alkyne, and conjugated to azide-terminated PEG by click chemistry. PEGylated MnL shows considerably higher relaxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e7b8e29e6ce1a71ff782071c663fcf9
https://doi.org/10.1039/c7ra09975d
https://doi.org/10.1039/c7ra09975d
Autor:
Zhi-Ting Cao, Hou-Bing Zhang, Zhe-Xiong Lian, Song Shen, Jun Wang, Yue Zhang, Ying-Li Luo, Cong-Fei Xu, Zhi-Bin Zhao, Gui Zhao, Jia Shi
Publikováno v:
Biomaterials. 217
Organ transplantation is the only effective method to treat end-stage organ failure. However, it is continuously plagued by immune rejection, which is mostly caused by T cell-mediated reactions. Dendritic cells (DCs) are professional antigen-presenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd3ac5df0f2b1b7073c997309067caf4
https://pubmed.ncbi.nlm.nih.gov/31271858
https://pubmed.ncbi.nlm.nih.gov/31271858