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pro vyhledávání: '"Hou Tommy Chen"'
Autor:
Brian Manning, Mary Campbell, Demetria Debartola, Michael G. Lopaze, Roger Swartz, Daniel W. Kung, Colin R. Rose, Bruce A. Posner, Zachary S. Hendsch, Richard F. Hank, Steven B. Coffey, Michael Fichtner, Christopher F. Wielis, Hou Tommy Chen, Rachel Kosa-Maines, Shawn Cabral, Stefanus J. Steyn, Philip A. Carpino, Wenhua Jiao, Jeffrey S. Dubins, Ryan Jones, Ingrid A. Stock, Kim F. McClure, Sam Varma
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 22:4281-4287
The discovery of spirocyclic piperidine-azetidine inverse agonists of the ghrelin receptor is described. The characterization and redressing of the issues associated with these compounds is detailed. An efficient three-step synthesis and a binding as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58acc6d592a140679459424947ba6c32
https://doi.org/10.1016/j.bmcl.2012.05.024
https://doi.org/10.1016/j.bmcl.2012.05.024
