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Akademický článek
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Publikováno v:
Environmental Health Perspectives, 1996 May 01. 104, 529-534.
Externí odkaz:
https://www.jstor.org/stable/3432817
Autor:
Jens Meiler, John A. Capra, Walter J. Chazin, Alexandra M Blee, Zachary D. Nagel, Bian Li, T J Pecen
Publikováno v:
Cancer Res
For precision medicine to reach its full potential for treatment of cancer and other diseases, protein variant effect prediction tools are needed to characterize variants of unknown significance (VUS) in a patient's genome with respect to their likel
Publikováno v:
Nat Protoc
Repair of DNA damage is a critical survival mechanism that impacts susceptibility to a variety of human diseases and represents a key target for cancer therapy. A major barrier to applying this knowledge in research and clinical translation has been
Autor:
Fangying Chen, Peng Wu, Lipeng Qiu, Keping Chen, Qi Tang, Xinyu Qi, Huiqin Chen, Zhaoyang Hu, Guohui Li
Publikováno v:
Pesticide Biochemistry and Physiology. 164:91-99
Baculoviruses have been developed as long-term and environmentally friendly biopesticides. However, solar ultraviolet radiation can reduce the activity of baculovirus. Radiation sensitive 23 (Rad23) can recognize DNA damage and is involved with nucle
Autor:
Valquiria Tiago dos Santos, Carlos Frederico Martins Menck, Clarissa Ribeiro Reily Rocha, Veridiana Munford, Leticia K. Lerner, Daniela T. Soltys, Camila Carrião Machado Garcia, Alain Sarasin, Natália Cestari Moreno
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Nucleotide excision repair (NER) is a conserved, flexible mechanism responsible for the removal of bulky, helix-distorting DNA lesions, like ultraviolet damage or cisplatin adducts, but its role in the repair of lesions generated by oxidative stress
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 1985 Oct 01. 82(19), 6622-6626.
Externí odkaz:
https://www.jstor.org/stable/26300
Autor:
Makoto Sugaya, Ryusuke Ono, Shinichi Sato, Yusuke Okuno, Kaoru Funamizu, Taisuke Kondo, Masashi Akiyama, Michihiro Kono, Chikako Nishigori
Publikováno v:
The Journal of dermatologyREFERENCES. 48(1)
A case of xeroderma pigmentosum (XP) group D in a 39-year-old Japanese man is reported. The patient had suffered from moderate to severe solar sensitivity and freckle-like pigmented macules in sun-exposed areas since 6 years of age, and developed ski
Publikováno v:
Biomolecules
Volume 10
Issue 6
Biomolecules, Vol 10, Iss 902, p 902 (2020)
Volume 10
Issue 6
Biomolecules, Vol 10, Iss 902, p 902 (2020)
The sustainment of replication and transcription of damaged DNA is essential for cell survival under genotoxic stress
however, the damage tolerance of these key cellular functions comes at the expense of fidelity. Thus, translesion DNA synthesis
however, the damage tolerance of these key cellular functions comes at the expense of fidelity. Thus, translesion DNA synthesis
Publikováno v:
Carcinogenesis
Deficiency in homologous recombination repair (HRR) capacity is frequently observed in breast tumors. However, whether HRR deficiency is a tumor-specific biomarker or a risk factor for breast cancer is unknown. In this two-stage study, using a host c