Zobrazeno 1 - 10
of 19 642
pro vyhledávání: '"Host defense"'
Subgenomic flaviviral RNAs and human proteins: in silico exploration of anti-host defense mechanisms
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 3527-3536 (2024)
Flaviviruses pose significant global health threats, infecting over 300 million people annually. Among their evasion strategies, the production of subgenomic flaviviral RNAs (sfRNAs) from the 3′ UTR of viral genomes is particularly notable. Utilizi
Externí odkaz:
https://doaj.org/article/9c439f4cfa5a4027b04305231bf9c89e
Autor:
Yamato Kuratani, Chika Abematsu, Keisuke Ekino, Takuji Oka, Masashi Shin, Makoto Iwata, Hiroto Ohta, Shoji Ando
Publikováno v:
FEBS Open Bio, Vol 14, Iss 11, Pp 1805-1824 (2024)
Mushrooms are the fruiting bodies of fungi and are important reproductive structures that produce and disseminate spores. The Pri3 gene was originally reported to be specifically expressed in the primordia (a precursor to the mature fruiting body) of
Externí odkaz:
https://doaj.org/article/9893933d45c34831918304de2b566bbf
Autor:
Tanvir Noor Nafiz, Poornima Sankar, Lokesh K. Mishra, Robert P. Rousseau, Mohd Saqib, Selvakumar Subbian, Suraj P. Parihar, Bibhuti B. Mishra
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Formyl peptide receptors (FPR), part of the G-protein coupled receptor superfamily, are pivotal in directing phagocyte migration towards chemotactic signals from bacteria and host tissues. Although their roles in acute bacterial infections a
Externí odkaz:
https://doaj.org/article/8fe56711e8f148898a30c000b82d8c2d
Autor:
Sazanami Mori, Natsuki Nakamura, Ayane Fuchigami, Satoshi Yoshimoto, Moe Sakakibara, Toshiyuki Ozawa, Junken Aoki, Asuka Inoue, Hayakazu Sumida, Hideya Ando, Motonao Nakamura
Publikováno v:
FASEB BioAdvances, Vol 6, Iss 10, Pp 424-441 (2024)
Abstract Bitter taste receptors (TAS2Rs) are not only expressed in the oral cavity but also in skin. Extraoral TAS2Rs are thought to be involved in non‐taste perception and tissue‐specific functions. Keratinocytes that express TAS2Rs in the skin
Externí odkaz:
https://doaj.org/article/87f2088083af4c1389595ee070e7630c
Autor:
Loïc Quevarec, Levi T. Morran, Elizabeth Dufourcq-Sekatcheff, Olivier Armant, Christelle Adam-Guillermin, Jean-Marc Bonzom, Denis Réale
Publikováno v:
BMC Ecology and Evolution, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Adaptation to a stressor can lead to costs on other traits. These costs play an unavoidable role on fitness and influence the evolutionary trajectory of a population. Host defense seems highly subject to these costs, possibly beca
Externí odkaz:
https://doaj.org/article/ec4ce81c685e4243a064fc9c5b4af008
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Background In triple-negative breast cancer (TNBC) therapy, insufficient tumor infiltration by lymphocytes significantly hinders the efficacy of immune checkpoint inhibitors. We have previously demonstrated that Hainanenin-1 (HN-1), a host d
Externí odkaz:
https://doaj.org/article/4e8922e57b7c443bbe67f7c718280b7a
Autor:
Hyeong Won Kim, Seokwon Shin, So Hui Park, Jong-Hyeon Park, Su-Mi Kim, Yoon-Hee Lee, Min Ja Lee
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionMany countries use commercial foot-and-mouth disease (FMD) vaccines to prevent FMD pandemics, but these vaccines have disadvantages, such as repeated vaccinations due to the short persistence of antibody (Ab) titers and incomplete host de
Externí odkaz:
https://doaj.org/article/0bfbf0e6402e44d497c21d04c3e80802
Autor:
Maria Luiza Thorstenberg, Monique Daiane Andrade Martins, Nathália Ferreira Oliveira, Matheus Macedo L.V. Monteiro, Gustavo R.C. Santos, Henrique M. Gualberto Pereira, Luiz Eduardo Baggio Savio, Robson Coutinho-Silva, Claudia Lucia Martins Silva
Publikováno v:
Biomedical Journal, Vol 47, Iss 6, Pp 100713- (2024)
Background: The occurrence of co-infections during schistosomiasis, a neglected tropical disease, with other parasites have been reported suggesting an impaired host immune defense. Macrophage purinergic P2X7 receptor (P2X7R) plays an important role
Externí odkaz:
https://doaj.org/article/b5876f95cef54269b28b05ae9f4672ec
Publikováno v:
Poultry Science, Vol 103, Iss 12, Pp 104339- (2024)
ABSTRACT: In this comparative study, the differential responses of heritage (ACRB; Athens Canadian Random Bred) and modern (Cobb) broilers to a necrotic enteritis (NE) challenge were evaluated. The design was a 2×2 factorial with breed (ACRB and Cob
Externí odkaz:
https://doaj.org/article/9e2b363916b34007a97c5f83224c8ff8
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The defense mechanisms of the vertebrate brain against infections are at the forefront of immunological studies. Unlike other body parts, the brain not only fends off pathogenic infections but also minimizes the risk of self-damage from immune cell i
Externí odkaz:
https://doaj.org/article/c9bba2108d554caeab49247846ca3f32