CRISPR/Cas9-Based Knockout of GNAQ Reveals Differences in Host Cell Signaling Necessary for Egress of Apicomplexan Parasites

Autor: Paul-Christian Burda, Hugo Bisio, Jean-Baptiste Marq, Dominique Soldati-Favre, Volker T. Heussler

Publikováno v: mSphere, Vol 5, Iss 6 (2020)

ABSTRACT Toxoplasma gondii and members of the genus Plasmodium are obligate intracellular parasites that leave their infected host cell upon a tightly controlled process of egress. Intracellular replication of the parasites occurs within a parasitoph

Externí odkaz: https://doaj.org/article/2982922e725b40bf8593d040936cc872

CRISPR/Cas9-Based Knockout of GNAQ Reveals Differences in Host Cell Signaling Necessary for Egress of Apicomplexan Parasites

Autor: Volker Heussler, Hugo Bisio, Jean-Baptiste Marq, Paul-Christian Burda, Dominique Soldati-Favre

Publikováno v: mSphere, Vol 5, Iss 6 (2020)
mSphere, Vol. 5, No 6 (2020) pp. e01001-20
Burda, Paul-Christian; Bisio, Hugo; Marq, Jean-Baptiste; Soldati-Favre, Dominique; Heussler, Volker (2020). CRISPR/Cas9-Based Knockout of GNAQ Reveals Differences in Host Cell Signaling Necessary for Egress of Apicomplexan Parasites. mSphere, 5(6) American Society for Microbiology 10.1128/mSphere.01001-20
mSphere

The coordinated release of apicomplexan parasites from infected host cells prior to reinvasion is a critical process for parasite survival and the spread of infection. While Toxoplasma tachyzoites and Plasmodium blood stages induce a fast disruption

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f371d629bf33d4e8f3c510918adde433
https://journals.asm.org/doi/10.1128/mSphere.01001-20

Impact of 4 Lactobacillus plantarum capsular polysaccharide clusters on surface glycan composition and host cell signaling

Autor: Remus Daniela M, van Kranenburg Richard, van Swam Iris I, Taverne Nico, Bongers Roger S, Wels Michiel, Wells Jerry M, Bron Peter A, Kleerebezem Michiel

Publikováno v: Microbial Cell Factories, Vol 11, Iss 1, p 149 (2012)

Abstract Background Bacterial cell surface-associated polysaccharides are involved in the interactions of bacteria with their environment and play an important role in the communication between pathogenic bacteria and their host organisms. Cell surfa

Externí odkaz: https://doaj.org/article/b025d5981cd94bf48b2f69725950045c

Interactions between Trypanosoma cruzi Secreted Proteins and Host Cell Signaling Pathways

Autor: Diana Bahia, José Franco da Silveira, Renata Watanabe Costa

Publikováno v: Frontiers in Microbiology
Frontiers in Microbiology, Vol 7 (2016)

Chagas disease is one of the prevalent neglected tropical diseases, affecting at least 6-7 million individuals in Latin America. It is caused by the protozoan parasite Trypanosoma cruzi (T. cruzi), which is transmitted to vertebrate hosts by blood-su

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::259116ec68a11aa970be37a1b0a24f25
https://doi.org/10.3389/fmicb.2016.00388

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