Zobrazeno 1 - 10
of 2 559
pro vyhledávání: '"Host Response and Inflammation"'
Autor:
Amber M. Frye, Monir Ejemel, Lisa Cavacini, Yang Wang, Michael J. Rudolph, Renjie Song, Nicholas J. Mantis
Publikováno v:
Infect Immun
Lyme disease vaccines based on recombinant Outer surface protein A (OspA) elicit protective antibodies that interfere with tick-to-host transmission of the disease-causing spirochete Borreliella burgdorferi. Another hallmark of OspA antisera and cert
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a236f0dffe87ab38481b83c2ed7c5749
https://pubmed.ncbi.nlm.nih.gov/36000876
https://pubmed.ncbi.nlm.nih.gov/36000876
Publikováno v:
Infect Immun
Acute lung injury (ALI) caused by sepsis is a common respiratory critical illness with high morbidity and mortality. Protein kinase C-alpha (PRKCA) plays a protective role in sepsis-induced ALI. However, the detailed molecular mechanism of PRKCA in A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68602b767be8b4c0a141c91707d238fb
https://doi.org/10.1128/iai.00465-22
https://doi.org/10.1128/iai.00465-22
Publikováno v:
Infect Immun
Despite an important link between the gut and ocular health, the role of the gut-eye axis remains elusive in ocular infections. In this study, we investigated the role of butyrate, a gut microbial metabolite, in the pathobiology of intraocular bacter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7498c84eccf986b13e9eabdd7341f1e
https://doi.org/10.1128/iai.00252-22
https://doi.org/10.1128/iai.00252-22
Autor:
Erin M. Harberts, Daniel Grubaugh, Daniel C. Akuma, Sunny Shin, Robert K. Ernst, Igor E. Brodsky
Publikováno v:
Infect Immun
Immune sensing of the Gram-negative bacterial membrane glycolipid lipopolysaccharide (LPS) is both a critical component of host defense against Gram-negative bacterial infection, and a contributor to hyper-inflammatory response, leading to sepsis and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2ccdc16221fb127dbc0bfd60accf37a
https://pubmed.ncbi.nlm.nih.gov/35862717
https://pubmed.ncbi.nlm.nih.gov/35862717
Autor:
Jasmine Alexander-Floyd, Antonia R. Bass, Erin M. Harberts, Daniel Grubaugh, Joseph D. Buxbaum, Igor E. Brodsky, Robert K. Ernst, Sunny Shin
Publikováno v:
Infect Immun
Detection of Gram-negative bacterial lipid A by the extracellular sensor, myeloid differentiation 2 (MD2)/Toll-like receptor 4 (TLR4), or the intracellular inflammasome sensors, CASP4 and CASP5, induces robust inflammatory responses. The chemical str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b8e590929650556dc6d5998e749dc08
https://pubmed.ncbi.nlm.nih.gov/35862709
https://pubmed.ncbi.nlm.nih.gov/35862709
Autor:
Kevin S, Johnson, Christina, Yang, J Elliot, Carter, Atesh K, Worthington, Elektra K, Robinson, Raymond, Lopez-Magaña, Frida, Salgado, Isabelle, Arnold, Karen M, Ottemann
Publikováno v:
Infect Immun
Helicobacter pylori colonizes half of the world’s population and is responsible for a significant disease burden by causing gastritis, peptic ulcers, and gastric cancer. The development of host inflammation drives these diseases, but there are stil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::315a4e71d0b61261aebcdbc7027378a5
https://pubmed.ncbi.nlm.nih.gov/36533917
https://pubmed.ncbi.nlm.nih.gov/36533917
Autor:
Thitinan Kasetthat, Ludthawun Kamuthachad, Rasana W. Sermswan, Hiroshi Watarai, Ponpan Matangkasombut, Surasakdi Wongratanacheewin
Publikováno v:
Infect Immun
Melioidosis is an infectious disease caused by Burkholderia pseudomallei. High interferon gamma (IFN-γ) levels in naive mice were reported to mediate protection against B. pseudomallei infection. Invariant natural killer T (iNKT) cells can produce a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9c2dec1c381a3b226ca2977c44806d6
https://pubmed.ncbi.nlm.nih.gov/36374098
https://pubmed.ncbi.nlm.nih.gov/36374098
Autor:
Annie N. Hinson, Colin G. Hawkes, Christopher S. Blake, Zackary R. Fitzsimonds, Bin Zhu, Gregory Buck, Richard J. Lamont, Daniel P. Miller
Publikováno v:
Infect Immun
The oral epithelial barrier acts as both a physical barrier to the abundant oral microbiome and a sentry for the immune system that, in health, constrains the accumulation of the polymicrobial plaque biofilm. The immune homeostasis during gingivitis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05f01ccdd48239e62502ad3c7cbb0660
https://europepmc.org/articles/PMC9584330/
https://europepmc.org/articles/PMC9584330/
Autor:
R. C. A. de Groot, H. Zhu, T. Hoogenboezem, A. C. J. M. de Bruijn, E. Eenjes, A. E. J. ’t Jong, A. I. Belo, S. C. Estevão, J. J. Bajramovic, R. J. Rottier, M. Kool, A. M. C. van Rossum, W. W. J. Unger
Publikováno v:
Infect Immun
Mycoplasma pneumoniae and Streptococcus pneumoniae are the most common bacterial causes of pneumonia in children. The clinical characteristics of pneumonia differ significantly between the two bacteria. We aimed to elucidate the differences in pathog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48ddca0c34e1bf1aea3e413862628675
https://doi.org/10.1128/iai.00129-22
https://doi.org/10.1128/iai.00129-22
Autor:
Nawar Naseer, Jenna Zhang, Renate Bauer, David A. Constant, Timothy J. Nice, Igor E. Brodsky, Isabella Rauch, Sunny Shin
Publikováno v:
Infect Immun
Salmonella enterica serovar Typhimurium is a Gram-negative pathogen that causes diseases ranging from gastroenteritis to systemic infection and sepsis. Salmonella uses type III secretion systems (T3SS) to inject effectors into host cells. While these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59324ea9a1a5baf8f6e8d12079f785bc
https://doi.org/10.1128/iai.00663-21
https://doi.org/10.1128/iai.00663-21