Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Host Defense & Pathophysiology"'
Autor:
Mohammad R. Toliat, Marek Franitza, Lieke Schoenmaker, Peter Nürnberg, Brendon P. Scicluna, Hina N. Khan, Aeilko H. Zwinderman, Desiree Perlee, Anne-Jan van der Meer, Tom van der Poll
Publikováno v:
Journal of leukocyte biology, 106(5), 1153-1160. FASEB
Journal of Leukocyte Biology
Journal of Leukocyte Biology
The host immune response is characterized by a complex interplay of signal‐specific cellular transcriptional responses. The magnitude of the immune response is dependent on the strength of the external stimulus. Knowledge on leukocyte transcription
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c5155637af704ab41a82bcdc66f0b7c
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85068641173&origin=inward
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85068641173&origin=inward
Autor:
Gamze Isitman, Nicole F. Bernard, Louise Gilbert, Sanket Kant, Irene Lisovsky, Alexandra Tremblay-McLean, Zahra Kiani, Julie Bruneau, Bertrand Lebouché, Franck P. Dupuy, Naglaa H. Shoukry
Publikováno v:
Journal of Leukocyte Biology
The engagement of activating NK receptors (aNKR) stimulates NK cell activity, provided that interactions between inhibitory NK receptors (iNKR) with their HLA ligands do not override them. Abs bound to target cells can also activate NK cells by engag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ac34f59a6d2d5ff746afa7d8444d735
http://europepmc.org/articles/PMC6916277
http://europepmc.org/articles/PMC6916277
Autor:
Reinout van Crevel, Lika Apriani, Vinod Kumar, Ayesha J Verrall, Valerie A. C. M. Koeken, Jéssica Cristina dos Santos, Leo A. B. Joosten, Edwin Ardiansyah, Philip C. Hill, Bachti Alisjahbana, Arjan van Laarhoven
Publikováno v:
Journal of Leukocyte Biology, 107, 113-118
Journal of Leukocyte Biology, 107, 1, pp. 113-118
Journal of Leukocyte Biology
Journal of Leukocyte Biology, 107, 1, pp. 113-118
Journal of Leukocyte Biology
Studies in IL‐32 transgenic mice and in vitro suggest that IL‐32 may have protective effects against Mycobacterium tuberculosis, but so far there are barely any studies in humans. We studied the role of IL‐32 and its splice variants in tubercul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecf73312aef64f7088aa4fa95d49b328
http://hdl.handle.net/2066/218685
http://hdl.handle.net/2066/218685
Calcineurin inhibitors reduce NFAT-dependent expression of antifungal pentraxin-3 by human monocytes
Autor:
Marco De Zuani, Silvie Bělašková, Marcela Hortová Kohoutková, Giancarlo Forte, Teresa Zelante, Kamila Bendíčková, Federico Tidu, Jan Fric, Ivana Andrejčinová, Antonio Pompeiano
Publikováno v:
Journal of Leukocyte Biology
Calcineurin (CN) inhibitors are effective clinical immunosuppressants but leave patients vulnerable to potentially fatal fungal infections. This study tested the hypothesis that CN inhibition interferes with antifungal immune defenses mediated by mon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d21286fde9fde7b9e4914270c27778c
http://hdl.handle.net/11391/1461379
http://hdl.handle.net/11391/1461379
Autor:
Shabaana A. Khader, Javier Rangel-Moreno, Uma M. Nagarajan, Mushtaq Ahmed, Hongmei Jiao, Racquel Domingo-Gonzalez, Shibali Das, Kristin L. Griffiths
Publikováno v:
Journal of Leukocyte Biology. 101:1373-1381
Pulmonary tuberculosis (TB) caused by Mycobacterium tuberculosis (Mtb) is a leading cause of global morbidity and mortality. The only licensed TB vaccine, Mycobacterium bovis bacillus Calmette-Guerin (BCG), has variable efficacy in protecting against
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90726e0ca3d7ed39ff17540c8c0bc1e8
https://doi.org/10.1189/jlb.4a0616-270r
https://doi.org/10.1189/jlb.4a0616-270r
Publikováno v:
Journal of Leukocyte Biology. 101:1253-1261
Herpes simplex virus type 1 (HSV-1) is a leading cause of neurotrophic keratitis (NTK). NTK is characterized by decreased corneal sensation from damage to the corneal sensory fibers. We have reported on the regression of corneal nerves and their func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8498565ba152b51efaee8390b3d44ac
https://doi.org/10.1189/jlb.4a1116-459r
https://doi.org/10.1189/jlb.4a1116-459r
Autor:
Nicholas J. Mantis, Jennifer Doering, Fernando J Torres-Velez, Dylan J. Ehrbar, Bridget Mooney
Publikováno v:
Journal of Leukocyte Biology
Ricin toxin is a plant‐derived, ribosome‐inactivating protein that is rapidly cleared from circulation by Kupffer cells (KCs) and liver sinusoidal endothelial cells (LSECs)—with fatal consequences. Rather than being inactivated, ricin evades no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::315e5dbdecaa8fd1563ee2e61e70ef46
https://pubmed.ncbi.nlm.nih.gov/31313388
https://pubmed.ncbi.nlm.nih.gov/31313388
Autor:
Jacqueline Unsinger, Grant V. Bochicchio, Tim Eitas, Anja Fuchs, Christopher G. Davis, Yuichiro Shindo, Carey-Ann D. Burnham, Jonathan M. Green, Richard S. Hotchkiss, Michel Morre
Publikováno v:
Journal of Leukocyte Biology. 101:543-554
Patients with protracted sepsis develop impaired immunity, which predisposes them to acquiring secondary infections. One of the most common and lethal secondary infections is Pseudomonas aeruginosa pneumonia. Immunoadjuvant therapy is a promising app
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a80039059717e18a3593bfc2567d27a
https://doi.org/10.1189/jlb.4a1215-581r
https://doi.org/10.1189/jlb.4a1215-581r
Autor:
Casey L. Gilmore, T. Scott Devera, Gillian A. Lang, Mark L. Lang, Pragya Rampuria, Jimmy D. Ballard
Publikováno v:
Journal of Leukocyte Biology. 101:567-576
Activation of iNKT cells with the CD1d-binding glycolipid adjuvant α-galactosylceramide (α-GC) enhances humoral immunity specific for coadministered T-dependent Ag. However, the relationship between the iNKT cell and the classic T helper (Th) or T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9433ef1346e5345fae38d5c916bcfd8
https://doi.org/10.1189/jlb.4a0616-271r
https://doi.org/10.1189/jlb.4a0616-271r
Publikováno v:
Journal of Leukocyte Biology. 101:339-350
HIV infection leads to CD4 helper T cell (Th) loss, but not all Th cells are equally depleted. The contribution of other immune cells in the Th depletion also remains unclear. This study investigates HIV transmission from monocyte-derived dendritic c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9fa7e7b1e387ef01c979ba4daba17c6
https://doi.org/10.1189/jlb.4a0516-216r
https://doi.org/10.1189/jlb.4a0516-216r