Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Hossein Noyan"'
Autor:
Jovan C.D. Hasmatali, Jolly De Guzman, Jayne M Johnston, Hossein Noyan, Bernhard H Juurlink, Vikram Misra, Valerie M.K. Verge
Publikováno v:
Neural Regeneration Research, Vol 15, Iss 12, Pp 2353-2361 (2020)
Emerging evidence supports that the stress response to peripheral nerve injury extends beyond the injured neuron, with alterations in associated transcription factors detected both locally and remote to the lesion. Stress-induced nuclear translocatio
Externí odkaz:
https://doaj.org/article/b53d84e889d84727b8b6116b67c5be86
Autor:
Eric A. Shikatani, Rickvinder Besla, Sherine Ensan, Aditi Upadhye, Nadiya Khyzha, Angela Li, Takuo Emoto, Felix Chiu, Norbert Degousee, Joshua M. Moreau, Heather M. Perry, Danya Thayaparan, Henry S. Cheng, Shaun Pacheco, David Smyth, Hossein Noyan, Caleb C.J. Zavitz, Carla M.T. Bauer, Ingo Hilgendorf, Peter Libby, Filip K. Swirski, Jennifer L. Gommerman, Jason E. Fish, Martin R. Stampfli, Myron I. Cybulsky, Barry B. Rubin, Christopher J. Paige, Timothy P. Bender, Coleen A. McNamara, Mansoor Husain, Clinton S. Robbins
Publikováno v:
Cell Reports, Vol 27, Iss 8, Pp 2304-2312.e6 (2019)
Summary: Mechanisms that govern transcriptional regulation of inflammation in atherosclerosis remain largely unknown. Here, we identify the nuclear transcription factor c-Myb as an important mediator of atherosclerotic disease in mice. Atherosclerosi
Externí odkaz:
https://doaj.org/article/739dd39d1f244a6f8144a50e8b09c4c0
Autor:
Hossein Noyan, Omar El-Mounayri, Ruth Isserlin, Sara Arab, Abdul Momen, Henry S Cheng, Jun Wu, Talat Afroze, Ren-Ke Li, Jason E Fish, Gary D Bader, Mansoor Husain
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0130658 (2015)
To understand the molecular pathways underlying the cardiac preconditioning effect of short-term caloric restriction (CR).Lifelong CR has been suggested to reduce the incidence of cardiovascular disease through a variety of mechanisms. However, prolo
Externí odkaz:
https://doaj.org/article/0895685294c44998ad3203da6672d25b
Autor:
Valerie M. K. Verge, Hossein Noyan, Jovan C D Hasmatali, Jayne M Johnston, Bernhard H.J. Juurlink, Vikram Misra, Jolly De Guzman
Publikováno v:
Neural Regeneration Research, Vol 15, Iss 12, Pp 2353-2361 (2020)
Neural Regeneration Research
Neural Regeneration Research
Emerging evidence supports that the stress response to peripheral nerve injury extends beyond the injured neuron, with alterations in associated transcription factors detected both locally and remote to the lesion. Stress-induced nuclear translocatio
Autor:
Yiming Wang, Omar El-Mounayri, Talat Afroze, Hossein Noyan, Heyu Ni, Alison Cameron-Vendrig, Xi Lei, Xiaohong Ruby Xu, Mansoor Husain, Adili Reheman, Eric A. Shikatani, M. Ahsan Siraj, Ralph Weissleder
Publikováno v:
Diabetes. 65:1714-1723
Short-term studies in subjects with diabetes receiving glucagon-like peptide 1 (GLP-1)–targeted therapies have suggested a reduced number of cardiovascular events. The mechanisms underlying this unexpectedly rapid effect are not known. We cloned fu
Autor:
Shaun Pacheco, Myron I. Cybulsky, Hossein Noyan, Angela Li, Martin R. Stämpfli, David J. Smyth, Joshua M. Moreau, Danya Thayaparan, Jennifer L. Gommerman, Mansoor Husain, Felix Chiu, Christopher J. Paige, Takuo Emoto, Filip K. Swirski, Carla M. T. Bauer, Nadiya Khyzha, Rickvinder Besla, Heather M. Perry, Aditi Upadhye, Ingo Hilgendorf, Coleen A. McNamara, Sherine Ensan, Peter Libby, Norbert Degousee, Eric A. Shikatani, Jason E. Fish, Caleb C. J. Zavitz, Timothy P. Bender, Henry S. Cheng, Clinton S. Robbins, Barry B. Rubin
Publikováno v:
Cell Reports, Vol 27, Iss 8, Pp 2304-2312.e6 (2019)
Summary: Mechanisms that govern transcriptional regulation of inflammation in atherosclerosis remain largely unknown. Here, we identify the nuclear transcription factor c-Myb as an important mediator of atherosclerotic disease in mice. Atherosclerosi
Autor:
Rafael Wolff, Kiet Tran, Mansoor Husain, Michael A. Kuliszewski, Howard Leong-Poi, Sang Yup Lim, Karin Tran-Lundmark, Beiping Qiang, Karl Tryggvason, Hossein Noyan, Bradley H. Strauss, Dmitriy Rudenko, Azriel B. Osherov, Ulf Hedin, Michael Lekas
Publikováno v:
Canadian Journal of Cardiology. 30:1444-1451
Perlecan is a heparan sulfate proteoglycan (HSPG) constituent of the extracellular matrix with roles in cell growth, differentiation, and angiogenesis. The role of the HS side chains in regulating in vivo angiogenesis after hind-limb ischemia is unkn
Autor:
Ren-Ke Li, Hossein Noyan, Abdul Momen, Mansoor Husain, Rüdiger von Harsdorf, Jun Wu, Xuetao Sun
Publikováno v:
Journal of Biological Chemistry. 289:16924-16935
p27(Kip1) (p27), a key regulator of cell division, has been implicated in autophagy of cancer cells. However, its role in autophagy, the evolutionarily conserved catabolic process that enables cells to remove unwanted proteins and damaged organelles,
Autor:
Eva Stefanski, Michael H. Gelb, Stephen S. H. Huang, Ali Danesh, Barry B. Rubin, Alberto J. Leόn, Gérard Lambeau, David Banner, Alyson A. Kelvin, Denis Angoulvant, David J. Kelvin, Norbert Degousee, Stéphane G. Paquette, Hossein Noyan, Mansoor Husain, Clinton S. Robbins
Publikováno v:
Virology
The role of Group X secreted phospholipase A2 (GX-sPLA2) during influenza infection has not been previously investigated. We examined the role of GX-sPLA2 during H1N1 pandemic influenza infection in a GX-sPLA2 gene targeted mouse (GX(-/-)) model and
Autor:
Irmgard Schuiki, Eric A. Shikatani, Jun Wu, Mohammad Hossein Noyan-Ashraf, Filio Billia, Ren-Ke Li, Allen Volchuk, Mansoor Husain, Lisa A. Robinson, Ilya Mukovozov, Daniel J. Drucker
Publikováno v:
Circulation. 127:74-85
Background— Cardiac consequences of obesity include inflammation, hypertrophy, and compromised energy metabolism. Glucagon-like peptide-1 is an incretin hormone capable of cytoprotective actions that reduces inflammation and endoplasmic reticulum s