Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Hossein Navabi"'
Autor:
Aled Clayton, Sharon Louise Coleman, Malcolm Adams, Zsuzsanna Tabi, Bharat Jasani, Hossein Navabi, Malcolm David Mason, D. Croston
Publikováno v:
ResearcherID
A clinical trial employing an immunotherapeutic approach based on the use of a Toll-like receptor 3 (TLR3) agonist and tumour-derived exosomes carrying tumour-associated antigens is planned in advanced ovarian cancer in conjunction with conventional
Autor:
Alison Nina Fiander, Cyril Donninger, Stephen Man, Malcolm Adams, Bharat Jasani, Malcolm David Mason, A. S. Evans, Hossein Navabi
Publikováno v:
Vaccine. 21:787-790
Human papilloma virus (HPV) found in 99.7% of cervical cancers represents an attractive immunotherapeutic target for novel adjuvant dendritic cell (DC) immunotherapy. DC primed with HPV antigens have been shown to be capable of inducing CTL responses
Autor:
Malcolm Adams, Geoff R. Newman, Hossein Navabi, Jacquelyn Court, Bharat Jasani, Malcolm David Mason, Jan A. Hobot, Aled Clayton
Publikováno v:
Journal of Immunological Methods. 247:163-174
We present a simple yet powerful method for the isolation and analysis of exosomes released by antigen-presenting cells (APC). Exosomes are small vesicles (40-90 nm) released by APC, and may have an immune-regulatory function in vivo. Such exosomes o
Publikováno v:
The Journal of Pathology. 184:144-147
Metallothionein (MT) overexpression occurs frequently in human tumours but the underlying mechanism is unknown. Morphologically normal-appearing mucosa from human colorectal carcinoma resection specimens and of the colons of ageing laboratory mice co
Autor:
Shokouh Taghipour Zahir, Fariba Binesh, Nasim Behniafard, Saied Arefanian, Saied Kargar, Hossein Navabi
Publikováno v:
Journal of Clinical & Experimental Pathology.
Background: Idiopathic granulomatous mastitis is a rare chronic inflammatory disease and typically occurs in women at the reproductive life. The etiology, clinical course, and optimal treatment of this disorder remain obscure. The most common clinica
Publikováno v:
Virchows Archiv. 430:373-379
Immunocytochemically detectable MT and p53 have been found more commonly in comedo DCIS of the breast with high-grade cytology. The aim of this study is to confirm these findings and to investigate the relationship between MT and p53 in a single larg
Publikováno v:
The Journal of Pathology. 174:223-228
Interest has recently been shown in adapting the microwave oven heating technique for antigen retrieval to routine diagnostic immunocytochemical practice. Although it has proved effective as a specialist method for individual antigen localization in
Autor:
N. D. Thomas, E. D. Williams, David M. Millar, Geoffrey R. Newman, Hossein Navabi, Julia Margaret Wendy Gee, Bharat Jasani
Publikováno v:
Journal of Immunological Methods. 150:193-198
Over the past 10 years an immunoperoxidase method using dinitrophenyl (DNP) hapten-labelled primary or secondary probes has been devised. Its widely successful application in research and diagnostic work has depended upon the development of certain k
Publikováno v:
Vaccine. 27(25-26)
Therapeutic vaccination against cancer-associated antigens represents an attractive option for cancer therapy in view of its potential efficacy, the possibility of long-lasting immunity against the cancer, and safety profile. Cancer patients are howe
Autor:
Ann Reece, Cyril Donninger, Hossein Navabi, Zsuzsanna Tabi, Bharat Jasani, Malcolm David Mason, Malcolm Adams, Aled Clayton
Publikováno v:
Vaccine. 27(1)
Maturation of dendritic cells (DC) can be triggered in vitro by inflammatory cytokines or Toll-like receptor (TLR) ligands such as CpG or polyI:C. Corresponding, well-characterized agents which can be applied in clinical settings are sparse.We have e