Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Hossein Mohammad Beigi"'
Autor:
Zahra Shakeran, Jaleh Varshosaz, Mehrnaz Keyhanfar, Hossein Mohammad-Beigi, Karim Rahimi, Duncan S. Sutherland
Publikováno v:
Artificial Cells, Nanomedicine, and Biotechnology, Vol 50, Iss 1, Pp 29-39 (2022)
Co-delivery of anticancer drugs and biologics can provide synergetic effects and outperform single delivery therapies. Here, a nanoparticle (NP) system for co-delivery of methotrexate (MTX) and STAT3 siRNA has been developed and tested in vitro. Meso
Externí odkaz:
https://doaj.org/article/0fae37188755466db48397df1d4e0bb6
Autor:
Mohammad hossein Asgarshamsi, Afshin Fassihi, Farshid Hassanzadeh, Lotfollah Saghaei, Ahmad Movahedian Attar, Hossein Mohammad-Beigi
Publikováno v:
Research in Pharmaceutical Sciences, Vol 16, Iss 1, Pp 35-47 (2021)
Background and purpose: Radicals produced by Fenton and Haber-Weiss reactions play detrimental roles in our body. Some oxidized proteins as toxic configurations are identified in amyloid-β deposits. These deposits mostly occur in conditions, such as
Externí odkaz:
https://doaj.org/article/a5b6891f573647cb9bc7e57858955069
Autor:
Hossein Mohammad-Beigi, Yuya Hayashi, Christina Moeslund Zeuthen, Hoda Eskandari, Carsten Scavenius, Kristian Juul-Madsen, Thomas Vorup-Jensen, Jan J. Enghild, Duncan S. Sutherland
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Understanding the biological identity of nanoparticles has mainly focused on the hard protein corona with the soft corona largely overlooked. Here, using click-chemistry, the authors report on a capture system for the identification of the soft coron
Externí odkaz:
https://doaj.org/article/35b5008eb572436fb96cdcb7e530c5c0
Autor:
Zahra Najarzadeh, Hossein Mohammad-Beigi, Jannik Nedergaard Pedersen, Gunna Christiansen, Jan Skov Pedersen, Janni Nielsen, Daniel E. Otzen
Publikováno v:
BBA Advances, Vol 2, Iss , Pp 100055- (2022)
Functional amyloids (FA) are proteins which are evolutionarily optimized to form highly stable fibrillar structures that strengthen the bacterial biofilm matrix. FA such as CsgA (E. coli) and FapC (Pseudomonas) are secreted to the bacterial surface w
Externí odkaz:
https://doaj.org/article/c917f718ac5c44b9b32e48c7b8b2d3fa
Publikováno v:
Soft Matter. 19:1549-1559
Mixing of alginate and β-lactoglobulin at pH < 5.2 results in complex coacervation. The coacervate network is formed by carboxylic acid resonance stabilization and charge–charge interactions. Heating of coacervates yields larger particles.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de4b97fa616dedf289152961064ec49a
https://doi.org/10.1039/d2sm01435a
https://doi.org/10.1039/d2sm01435a
Autor:
Hossein Mohammad-Beigi, Lars Kjaer, Hoda Eskandari, Farhang Aliakbari, Gunna Christiansen, Gianluca Ruvo, Jane L. Ward, Daniel Erik Otzen
Publikováno v:
Frontiers in Plant Science, Vol 10 (2019)
The ability of proteins to aggregate to form well-organized β-sheet rich amyloid fibrils is increasingly viewed as a general if regrettable property of the polypeptide chain. Aggregation leads to diseases such as amyloidosis and neurodegeneration in
Externí odkaz:
https://doaj.org/article/752a9179f32e442f8706c3796ab6e2c5
Autor:
Masoumeh Souri, Mohammad Aref Bagherzadeh, Mirza Ali Mofazzal Jahromi, Hossein Mohammad‐Beigi, Amir Abdoli, Hamed Mir, Abazar Roustazadeh, Majid Pirestani, Parham Sahandi Zangabad, Jafar Kiani, Amirmahmoud Bakhshayesh, Mehdi Jahani, Mohammad Taghi Joghataei, Mahdi Karimi
Publikováno v:
Souri, M, Bagherzadeh, M A, Jahromi, M A M, Mohammad-Beigi, H, Abdoli, A, Mir, H, Roustazadeh, A, Pirestani, M, Zangabad, P S, Kiani, J, Bakhshayesh, A, Jahani, M, Joghataei, M T & Karimi, M 2022, ' Poly-L-Lysine/Hyaluronan Nanocarriers As a Novel Nanosystem for Gene Delivery ', Journal of Microscopy, vol. 287, no. 1, pp. 32-44 . https://doi.org/10.1111/jmi.13107
The present research comes up with a novel DNA-loaded poly-l-lysine (PLL) / hyaluronan (HA) nanocarrier (DNA-loaded PLL/HA NCs) for gene delivery applications, as a promising candidate for gene delivery into diverse cells. A straightforward approach
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f0e8c1dd47e240bee6d9679767a9e6b
https://doi.org/10.1111/jmi.13107
https://doi.org/10.1111/jmi.13107
Autor:
Hossein Mohammad-Beigi, Masumeh Zanganeh, Carsten Scavenius, Hoda Eskandari, Azad Farzadfard, Seyed Abbas Shojaosadati, Jan J. Enghild, Daniel E. Otzen, Alexander K. Buell, Duncan S. Sutherland
Publikováno v:
Mohammad-Beigi, H, Zanganeh, M, Scavenius, C, Eskandari, H, Farzadfard, A, Shojaosadati, S A, Enghild, J J, Otzen, D E, Buell, A K & Sutherland, D S 2022, ' A Protein Corona Modulates Interactions of α-Synuclein with Nanoparticles and Alters the Rates of the Microscopic Steps of Amyloid Formation ', ACS Nano, vol. 16, no. 1, pp. 1102-1118 . https://doi.org/10.1021/acsnano.1c08825
Nanoparticles (NPs) can modulate protein aggregation and fibril formation in the context of amyloid diseases. Understanding the mechanism of this action remains a critical next step in developing nanomedicines for the treatment or prevention of Parki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d154ffa4138fb54307b4bc947337e0cd
https://doi.org/10.1021/acsnano.1c08825
https://doi.org/10.1021/acsnano.1c08825
Autor:
Hossein Mohammad-Beigi, Wahyu Wijaya, Mikkel Madsen, Yuya Hayashi, Ruifen Li, Tijs Albert Maria Rovers, Tanja Christine Jæger, Alexander K. Buell, Anni Bygvrå Hougaard, Jacob J.K. Kirkensgaard, Peter Westh, Richard Ipsen, Birte Svensson
Publikováno v:
Mohammad-Beigi, H, Wijaya, W, Madsen, M, Hayashi, Y, Li, R, Maria Rovers, T A, Jæger, T C, Buell, A K, Hougaard, A B, Kirkensgaard, J J K, Westh, P, Ipsen, R & Svensson, B 2023, ' Association of caseins with β-lactoglobulin influenced by temperature and calcium ions : A multi-parameter analysis ', Food Hydrocolloids, vol. 137, 108373 . https://doi.org/10.1016/j.foodhyd.2022.108373
Mohammad-Beigi, H, Wijaya, W, Madsen, M, Hayashi, Y, Li, R, Maria Rovers, T A, Jæger, T C, Buell, A K, Hougaard, A B, Kirkensgaard, J J K, Westh, P, Ipsen, R & Svensson, B 2023, ' Association of caseins with β-lactoglobulin influenced by temperature and calcium ions: A multi-parameter analysis ', Food Hydrocolloids, vol. 137, 108373 . https://doi.org/10.1016/j.foodhyd.2022.108373
Mohammad-Beigi, H, Wijaya, W, Madsen, M, Hayashi, Y, Li, R, Maria Rovers, T A, Jæger, T C, Buell, A K, Hougaard, A B, Kirkensgaard, J J K, Westh, P, Ipsen, R & Svensson, B 2023, ' Association of caseins with β-lactoglobulin influenced by temperature and calcium ions: A multi-parameter analysis ', Food Hydrocolloids, vol. 137, 108373 . https://doi.org/10.1016/j.foodhyd.2022.108373
Aggregation of the major whey protein in bovine milk, β-lactoglobulin (β-Lg) is strongly influenced by association with caseins (CNs). Here, by using combined differential scanning fluorimetry and dynamic light scattering, the conformational stabil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d715ed0e9f5cb1740e2f7432d4f0aa61
https://curis.ku.dk/portal/da/publications/association-of-caseins-with-lactoglobulin-influenced-by-temperature-and-calcium-ions(501ddf00-5fbd-440e-84e4-c75fc3539eaa).html
https://curis.ku.dk/portal/da/publications/association-of-caseins-with-lactoglobulin-influenced-by-temperature-and-calcium-ions(501ddf00-5fbd-440e-84e4-c75fc3539eaa).html
Autor:
Zahra Najarzadeh, Hossein Mohammad-Beigi, Jannik Nedergaard Pedersen, Gunna Christiansen, Thorbjørn Vincent Sønderby, Seyed Abbas Shojaosadati, Dina Morshedi, Kristian Strømgaard, Georg Meisl, Duncan Sutherland, Jan Skov Pedersen, Daniel E. Otzen
Publikováno v:
Biomolecules, Vol 9, Iss 11, p 659 (2019)
Self-assembly of proteins to β-sheet rich amyloid fibrils is commonly observed in various neurodegenerative diseases. However, amyloid also occurs in the extracellular matrix of bacterial biofilm, which protects bacteria from environmental stress an
Externí odkaz:
https://doaj.org/article/bbf2bc4a8ca04960946786765ab495de