Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Hossein Khorramde"'
Publikováno v:
BMC Immunology, Vol 25, Iss 1, Pp 1-10 (2024)
Abstract Background Despite the development of various antiviral drugs, most of them are not effective in the treatment of coronavirus disease 2019 (COVID-19) as a hyperinflammatory disorder. Chemokine (C-C motif) ligand 2 (CCL2) is one of the critic
Externí odkaz:
https://doaj.org/article/589897b0df6c46438be1a99e83de1986
Publikováno v:
Journal of Hematology & Oncology, Vol 17, Iss 1, Pp 1-66 (2024)
Abstract Pancreatic cancer is a major cause of cancer-related death, but despondently, the outlook and prognosis for this resistant type of tumor have remained grim for a long time. Currently, it is extremely challenging to prevent or detect it early
Externí odkaz:
https://doaj.org/article/754012d6328b4b0cbf9d194a95e3cec0
Autor:
Maryam Masoumi, Ali Bayat Bodaghi, Hossein Khorramdelazad, Erfan Ebadi, Sheyda Houshmandfar, Ali Saeedi-Boroujeni, Jafar Karami
Publikováno v:
Heliyon, Vol 10, Iss 15, Pp e35445- (2024)
The article delves into the pathogenesis of systemic sclerosis (SSc) with an emphasis on immunometabolism dysfunctions. SSc is a complex autoimmune connective tissue disorder with skin and organ fibrosis manifestation, vasculopathy, and immune dysreg
Externí odkaz:
https://doaj.org/article/1250c021cd6445e79eed57e0de48cef9
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Osteoarthritis (OA) is characterized by a complex interplay of molecular signals orchestrated by the CCL2/CCR2 axis. The pathogenesis of OA has been revealed to be influenced by a multifaceted effect of CCL2/CCR2 signaling on inflammation, cartilage
Externí odkaz:
https://doaj.org/article/7545c8b940a740b18a5d6020d30d0e93
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Clobenpropit is a histamine H3 receptor antagonist and has developed as a potential therapeutic drug due to its ability to inhibit CXCR4, a chemokine receptor involved in autoimmune diseases and cancer pathogenesis. The CXCL12/CXCR4 axis involves sev
Externí odkaz:
https://doaj.org/article/64b4ca7ba62b444288efd366d8652684
Publikováno v:
BMC Immunology, Vol 25, Iss 1, Pp 1-8 (2024)
Abstract Background The human interleukin-17 (IL-17) family comprises IL-17A to IL-17 F; their receptors are IL-17RA to IL-17RE. Evidence revealed that these cytokines can have a tumor-supportive or anti-tumor impact on human malignancies. The purpos
Externí odkaz:
https://doaj.org/article/0b1e70baf9084f1ba73e8815cd352ecd
Publikováno v:
Biomarker Research, Vol 12, Iss 1, Pp 1-26 (2024)
Abstract Mesenchymal stromal/stem cells (MSCs) are used in many studies due to their therapeutic potential, including their differentiative ability and immunomodulatory properties. These cells perform their therapeutic functions by using various mech
Externí odkaz:
https://doaj.org/article/232b6a94085742bcb843645ce2148654
Autor:
Zahra Kamiab, Hossein Khorramdelazad, Mehdi Kafi, Abdollah Jafarzadeh, Vahid Mohammadi-Shahrokhi, Zahra Bagheri-Hosseinabadi, Pooya Saeed Askari, Mitra Abbasifard
Publikováno v:
Advances in Rheumatology, Vol 64, Iss 1, Pp 1-8 (2024)
Abstract Background Interleukin-17 (IL-17) family plays a role in the pathogenesis of knee osteoarthritis (KOA) by contributing to the inflammatory and destructive processes in the affected joint. This study aimed to measure levels of IL-17 A and IL-
Externí odkaz:
https://doaj.org/article/7e298de3817744ce85d5a06037cf9e40
Autor:
Mohammad Hossein Razizadeh, Alireza Zafarani, Mahsa Taghavi-Farahabadi, Hossein Khorramdelazad, Sara Minaeian, Mohammad Mahmoudi
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-22 (2023)
Abstract Innate immunity is the first line of the host immune system to fight against infections. Natural killer cells are the innate immunity lymphocytes responsible for fighting against virus-infected and cancerous cells. They have various mechanis
Externí odkaz:
https://doaj.org/article/b76bbd1f6fce453f9fcd884835cca20d
Autor:
Fereshteh Rezagholizadeh, Fatemeh Tajik, Morteza Talebi, Seyed Reza Taha, Mahdieh Shariat Zadeh, Pooya Farhangnia, Hamideh Sadat Hosseini, Aram Nazari, Shabnam Mollazadeh Ghomi, Seyede Mahtab Kamrani Mousavi, Niloofar Haeri Moghaddam, Hossein Khorramdelazad, Mohammad Taghi Joghataei, Elahe Safari
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionPancreatic cancer is a truculent disease with limited treatment options and a grim prognosis. Immunotherapy has shown promise in treating various types of cancer, but its effectiveness in pancreatic cancer has been lacking. As a result, i
Externí odkaz:
https://doaj.org/article/2175ba54abcb4962a68c77d13e9df6ab