Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Hossein Batebi"'
Autor:
Makaía M. Papasergi-Scott, Guillermo Pérez-Hernández, Hossein Batebi, Yang Gao, Gözde Eskici, Alpay B. Seven, Ouliana Panova, Daniel Hilger, Marina Casiraghi, Feng He, Luis Maul, Peter Gmeiner, Brian K. Kobilka, Peter W. Hildebrand, Georgios Skiniotis
Publikováno v:
bioRxiv
SummaryG protein-coupled receptors (GPCRs) activate heterotrimeric G proteins by stimulating the exchange of guanine nucleotide in the Gα subunit. To visualize this mechanism, we developed a time-resolved cryo-EM approach that examines the progressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6024f692aea102cdca85b66e07b494c8
https://doi.org/10.1101/2023.03.20.533387
https://doi.org/10.1101/2023.03.20.533387
Autor:
Jie Heng, Xiangyu Liu, Xiuyan Ma, Changwen Jin, Hongwei Li, Xiaogang Niu, Hossein Batebi, Yunfei Hu, Peter W. Hildebrand, Brian K. Kobilka, Jun Xu
Publikováno v:
Proceedings of the National Academy of Sciences. 117:23096-23105
The β2-adrenergic receptor (β2AR) is a prototypical G protein-coupled receptor (GPCR) that preferentially couples to the stimulatory G protein Gs and stimulates cAMP formation. Functional studies have shown that the β2AR also couples to inhibitory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65646b74aa837a8b6b34b617826fa9a1
https://doi.org/10.1073/pnas.2009786117
https://doi.org/10.1073/pnas.2009786117
Autor:
Xiuyan, Ma, Yunfei, Hu, Hossein, Batebi, Jie, Heng, Jun, Xu, Xiangyu, Liu, Xiaogang, Niu, Hongwei, Li, Peter W, Hildebrand, Changwen, Jin, Brian K, Kobilka
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Recent structures of GPCRs in complex with G proteins provide important insights into G protein activation by family A and family B GPCRs; however, important questions remain. We don’t fully understand the mechanism of G protein coupli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2b14fd668d7111c774235bb08c18859b
https://pubmed.ncbi.nlm.nih.gov/32868434
https://pubmed.ncbi.nlm.nih.gov/32868434
Autor:
Daniel Huster, Mathias Bosse, Peter W. Hildebrand, Hossein Batebi, Marcel Gauglitz, Johanna K. S. Tiemann, Alexander Vogel
Publikováno v:
Biophysical Journal. 118:528a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86b277f52daa5893a3697ed41b9a3f88
https://doi.org/10.1016/j.bpj.2019.11.2901
https://doi.org/10.1016/j.bpj.2019.11.2901
Publikováno v:
Proteins. 86(4)
Apurinic/apyrimidinic endonuclease 1 (Ape1) is an important metal-dependent enzyme in the base excision repair mechanism, responsible for the backbone cleavage of abasic DNA through a phosphate hydrolysis reaction. Molecular dynamics simulations of A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edc64081a02290174a47653900bdfe4b
https://pubmed.ncbi.nlm.nih.gov/29344998
https://pubmed.ncbi.nlm.nih.gov/29344998
Autor:
Xiuyan Ma, Yunfei Hu, Hossein Batebi, Jie Heng, Jun Xu, Xiangyu Liu, Xiaogang Niu, Hongwei Li, Hildebrand, Peter W., Changwen Jin, Kobilka, Brian K.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 9/15/2020, Vol. 117 Issue 37, p1-10, 10p
Autor:
Hossein Batebi, Petra Imhof
Publikováno v:
Theoretical Chemistry Accounts. 135
Computation of phosphodiester hydrolysis in different models with one or two metal ions, representing typical active site architectures of nucleases, reveals an associative mechanism to be favorable in all of the cases studied in this work. Direct at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bb659ce9e19a9bd63a96e01448a4837
https://doi.org/10.1007/s00214-016-2020-8
https://doi.org/10.1007/s00214-016-2020-8
Publikováno v:
Organometallics. 30:6218-6224
In this study, we have used density functional theory to identify a new mechanism for the formation of carboxylate compounds from heteroarenes, such as benzoxazole, in the presence of copper catalysts. This new mechanism involves the formation of a c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::001de3f49976ae921feed844a2f0acf9
https://doi.org/10.1021/om200744a
https://doi.org/10.1021/om200744a
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 86:C4-C4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73181f82c1174521cb735f00d5d7d066
https://doi.org/10.1002/prot.25481
https://doi.org/10.1002/prot.25481