Zobrazeno 1 - 10
of 631
pro vyhledávání: '"Hossein Ardeschir, Ghofrani"'
Autor:
Athiththan Yogeswaran, Bruno Brito da Rocha, Zvonimir A. Rako, Samuel J. Kaufmann, Simon Schäfer, Nils Kremer, Hossein Ardeschir Ghofrani, Werner Seeger, Khodr Tello
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Impaired respiratory variation of right atrial pressure (RAP) in severe pulmonary hypertension (PH) suggests difficulty tolerating increased preload during inspiration. Our study explores whether this impairment links to specific factors: ri
Externí odkaz:
https://doaj.org/article/7dd15e3fd4434470923cbcf2f62a01a4
Autor:
Max Wissmüller, Panagiota Xanthouli, Nicola Benjamin, Ekkehard Grünig, Manuel J. Richter, Henning Gall, Hossein Ardeschir Ghofrani, Simon Herkenrath, Dirk Skowasch, Carmen Pizarro, Michael Halank, Christopher Hohmann, Martin Hellmich, Felix Gerhardt, Stephan Rosenkranz
Publikováno v:
ESC Heart Failure, Vol 9, Iss 5, Pp 2873-2885 (2022)
Abstract Aims Guideline recommendations highlight the critical role of combination therapy for the treatment of pulmonary arterial hypertension (PAH). Conversely, registry data demonstrate that a considerable number of PAH patients remain on monother
Externí odkaz:
https://doaj.org/article/67c894d4e963415ba31c6457b88091e3
Autor:
Athiththan Yogeswaran, Zvonimir A. Rako, Selin Yildiz, Hossein Ardeschir Ghofrani, Werner Seeger, Bruno Brito da Rocha, Henning Gall, Nils C. Kremer, Philipp Douschan, Silvia Papa, Carmine Dario Vizza, Domenico Filomena, Ryan J. Tedford, Robert Naeije, Manuel J. Richter, Roberto Badagliacca, Khodr Tello
Publikováno v:
ERJ Open Research, Vol 9, Iss 5 (2023)
Background Right ventricular (RV) diastolic dysfunction may be prognostic in pulmonary hypertension (PH). However, its assessment is complex and relies on conductance catheterisation. We aimed to evaluate echocardiography-based parameters as surrogat
Externí odkaz:
https://doaj.org/article/c85bc48591ed407c9f3a3d167f8b3a72
Autor:
Faeq Husain‐Syed, Narayana Sarma V. Singam, Jason K. Viehman, Lisa Vaughan, Pascal Bauer, Henning Gall, Khodr Tello, Manuel J. Richter, Athiththan Yogeswaran, Gregorio Romero‐González, Mitchell H. Rosner, Claudio Ronco, Birgit Assmus, Hossein Ardeschir Ghofrani, Werner Seeger, Horst‐Walter Birk, Kianoush B. Kashani
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 16 (2023)
Background The impact of changes in Doppler‐derived kidney venous flow in heart failure (HF) is not well studied. We aimed to investigate the association of Doppler‐derived kidney venous stasis index (KVSI) and intrakidney venous‐flow (IKVF) pa
Externí odkaz:
https://doaj.org/article/697e3f049fe84811b02e41f02130c572
Autor:
Athiththan Yogeswaran, Daniel Zedler, Manuel J. Richter, Sonja Steinke, Zvonimir A. Rako, Nils C. Kremer, Friedrich Grimminger, Werner Seeger, Hossein Ardeschir Ghofrani, Henning Gall, Khodr Tello
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
BackgroundCardiac interactions with organs such as the liver or kidneys have been described in different cardiovascular diseases. However, the clinical relevance of hepatorenal dysfunction in chronic thromboembolic pulmonary hypertension (CTEPH) rema
Externí odkaz:
https://doaj.org/article/620c8889029549fd87fd7d0d8f09a655
Autor:
Athiththan Yogeswaran, Manuel J. Richter, Faeq Husain-Syed, Zvonimir Rako, Natascha Sommer, Friedrich Grimminger, Werner Seeger, Hossein Ardeschir Ghofrani, Henning Gall, Khodr Tello
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
BackgroundVolume overload is often associated with clinical deterioration in precapillary pulmonary hypertension (PH). However, thorough assessment of volume overload is complex and therefore not routinely performed. We examined whether estimated pla
Externí odkaz:
https://doaj.org/article/e628a6b779b1494c94db2080b53ed843
Autor:
Dirk Bandorski, Sebastian Heibel, Reinhard Höltgen, Harilaos Bogossian, Hossein Ardeschir Ghofrani, Markus Zarse, Henning Gall
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
BackgroundIn patients with pulmonary hypertension (PH), increased pulmonary vascular resistance (PVR) may lead to increased right ventricular afterload and cardiac remodelling, potentially providing the substrate for ventricular arrhythmias. Studies
Externí odkaz:
https://doaj.org/article/c84f156054d840c1b8857d620f735348
Autor:
Christina A. Eichstaedt, Zoe Saßmannshausen, Memoona Shaukat, Ding Cao, Panagiota Xanthouli, Henning Gall, Natascha Sommer, Hossein-Ardeschir Ghofrani, Hans-Jürgen Seyfarth, Marianne Lerche, Michael Halank, Janina Kleymann, Nicola Benjamin, Satenik Harutyunova, Benjamin Egenlauf, Katrin Milger, Stephan Rosenkranz, Ralf Ewert, Hans Klose, Marius M. Hoeper, Karen M. Olsson, Mareike Lankeit, Tobias J. Lange, Katrin Hinderhofer, Ekkehard Grünig
Publikováno v:
Respiratory Research, Vol 23, Iss 1, Pp 1-12 (2022)
Abstract Background A genetic predisposition can lead to the rare disease pulmonary arterial hypertension (PAH). Most mutations have been identified in the gene BMPR2 in heritable PAH. However, as of today 15 further PAH genes have been described. Th
Externí odkaz:
https://doaj.org/article/1de528004b62464999a9e805a210de5e
Autor:
Robert P. Frantz, Raymond L. Benza, Richard N. Channick, Kelly Chin, Luke S. Howard, Vallerie V. McLaughlin, Olivier Sitbon, Roham T. Zamanian, Anna R. Hemnes, Matt Cravets, Jean‐Marie Bruey, Robert Roscigno, David Mottola, Erin Elman, Lawrence S. Zisman, Hossein‐Ardeschir Ghofrani
Publikováno v:
Pulmonary Circulation, Vol 11, Iss 4, Pp 1-7 (2021)
Aberrant kinase signaling that involves platelet‐derived growth factor receptor (PDGFR) α/β, colony stimulating factor 1 receptor (CSF1R), and stem cell factor receptor (c‐KIT) pathways may be responsible for vascular remodeling in pulmonary ar
Externí odkaz:
https://doaj.org/article/e7c6ee3ea34a41f89721a2c6c04b54de
Autor:
Tatyana Novoyatleva, Nabham Rai, Baktybek Kojonazarov, Swathi Veeroju, Isabel Ben-Batalla, Paola Caruso, Mazen Shihan, Nadine Presser, Elsa Götz, Carina Lepper, Sebastian Herpel, Grégoire Manaud, Frédéric Perros, Henning Gall, Hossein Ardeschir Ghofrani, Norbert Weissmann, Friedrich Grimminger, John Wharton, Martin Wilkins, Paul D. Upton, Sonja Loges, Nicholas W. Morrell, Werner Seeger, Ralph T. Schermuly
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-16 (2021)
Novoyatleva et al investigate the role of receptor tyrosine kinase Axl in Pulmonary arterial hypertension (PAH), finding that the small molecule inhibitor R428 reduces human pulmonary arterial smooth muscle cells proliferation and migration, but caus
Externí odkaz:
https://doaj.org/article/9cdae1283c834b96804aa01aec8d92af