Zobrazeno 1 - 10
of 228
pro vyhledávání: '"Hossein Ardehali"'
Autor:
Yuki Tatekoshi, Chunlei Chen, Jason Solomon Shapiro, Hsiang-Chun Chang, Malorie Blancard, Davi M Lyra-Leite, Paul W Burridge, Matthew Feinstein, Richard D'Aquila, Priscilla Hsue, Hossein Ardehali
Publikováno v:
eLife, Vol 13 (2024)
Heart failure with preserved ejection fraction (HFpEF) is commonly found in persons living with HIV (PLWH) even when antiretroviral therapy suppresses HIV viremia. However, studying this condition has been challenging because an appropriate animal mo
Externí odkaz:
https://doaj.org/article/d554a4e305244435abefadbdb0b10274
Autor:
Manuel A. Torres Acosta, Sidhanth Chandra, Sophia Li, Esther Yoon, Daniel Selgrade, Jeanne Quinn, Hossein Ardehali
Publikováno v:
BMC Medical Education, Vol 23, Iss 1, Pp 1-11 (2023)
Abstract Dual-degree MD-PhD programs have historically lacked diversity of race, ethnicity, gender, sexual orientation, and other facets of identity. Like MD- and PhD-granting programs, MD-PhD program training environments are also marked by structur
Externí odkaz:
https://doaj.org/article/f0e00d043d724fcaa2f074934689dc07
Autor:
Carolina M. Pusec, Vladimir Ilievski, Adam De Jesus, Zeenat Farooq, Joseph L. Zapater, Nadia Sweis, Hagar Ismail, Md Wasim Khan, Hossein Ardehali, Jose Cordoba-Chacon, Brian T. Layden
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract A primary role of the liver is to regulate whole body glucose homeostasis. Glucokinase (GCK) is the main hexokinase (HK) expressed in hepatocytes and functions to phosphorylate the glucose that enters via GLUT transporters to become glucose-
Externí odkaz:
https://doaj.org/article/071b50d72cdc40519a71ce57d0f855c6
Autor:
Xiaoyan Yang, Hsiang-Chun Chang, Yuki Tatekoshi, Amir Mahmoodzadeh, Maryam Balibegloo, Zeinab Najafi, Rongxue Wu, Chunlei Chen, Tatsuya Sato, Jason Shapiro, Hossein Ardehali
Publikováno v:
eLife, Vol 12 (2023)
Sirtuins (SIRT) exhibit deacetylation or ADP-ribosyltransferase activity and regulate a wide range of cellular processes in the nucleus, mitochondria, and cytoplasm. The role of the only sirtuin that resides in the cytoplasm, SIRT2, in the developmen
Externí odkaz:
https://doaj.org/article/befc7f16030043058f3f817b757b66ac
Publikováno v:
STAR Protocols, Vol 4, Iss 1, Pp 102064- (2023)
Summary: Impaired mitochondrial iron metabolism is associated with aging and a variety of diseases, and there is a growing need to accurately quantify mitochondrial iron levels. This protocol provides an optimized method for evaluating non-heme and h
Externí odkaz:
https://doaj.org/article/81e1c7f5b98b446aa9e1bbfe57baef27
Autor:
Hossein Ardehali
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 24 (2022)
Externí odkaz:
https://doaj.org/article/bdce06e78af84d6f9aacb3cc8320dfe4
Autor:
Adam De Jesus, Carolina M. Pusec, Tivoli Nguyen, Farnaz Keyhani-Nejad, Peng Gao, Samuel E. Weinberg, Hossein Ardehali
Publikováno v:
STAR Protocols, Vol 3, Iss 4, Pp 101668- (2022)
Summary: Peritoneal macrophages (PMs) have been shown to have higher stability compared to other macrophage subtypes. However, obtaining enough PMs from a single mouse is often a limitation for metabolomics analysis. Here, we describe a protocol to i
Externí odkaz:
https://doaj.org/article/8bcc30acc21e4e88b2cf23a6383aa7a7
Autor:
Hidemichi Kouzu, Yuki Tatekoshi, Hsiang-Chun Chang, Jason S. Shapiro, Warren A. McGee, Adam De Jesus, Issam Ben-Sahra, Zoltan Arany, Jonathan Leor, Chunlei Chen, Perry J. Blackshear, Hossein Ardehali
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 10 (2022)
Pregnancy is associated with substantial physiological changes of the heart, and disruptions in these processes can lead to peripartum cardiomyopathy (PPCM). The molecular processes that cause physiological and pathological changes in the heart durin
Externí odkaz:
https://doaj.org/article/ce1ae0e9ad7f4a358703ee95ae7ff468
Publikováno v:
eLife, Vol 11 (2022)
Iron is an essential molecule for biological processes, but its accumulation can lead to oxidative stress and cellular death. Due to its oxidative effects, iron accumulation is implicated in the process of aging and neurodegenerative diseases. Howeve
Externí odkaz:
https://doaj.org/article/2ccba3a385ad490398380fb814d3bb85
Publikováno v:
JCI Insight, Vol 6, Iss 13 (2021)
The emergence of the novel SARS coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), has resulted in an unprecedented pandemic that has been accompanied by a global health crisis. Although the lungs are the main org
Externí odkaz:
https://doaj.org/article/fea1919af2374039a7406527df369be2