Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Hossein A. Ghanbari"'
Autor:
Noa G. Holtzman, Michael S. Lebowitz, Rima Koka, Maria R. Baer, Kanam Malhotra, Amir Shahlaee, Hossein A. Ghanbari, Søren M. Bentzen, Ashkan Emadi
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundAspartate β-hydroxylase (ASPH) is an embryonic transmembrane protein aberrantly upregulated in cancer cells, associated with malignant transformation and, in some reports, with poor clinical prognosis.ObjectiveTo report the expression patt
Externí odkaz:
https://doaj.org/article/f86fb60e39bc4aa5ab5969a96ee00ea4
Publikováno v:
International Journal of Molecular Sciences, Vol 14, Iss 12, Pp 24438-24475 (2013)
Living cells continually generate reactive oxygen species (ROS) through the respiratory chain during energetic metabolism. ROS at low or moderate concentration can play important physiological roles. However, an excessive amount of ROS under oxidativ
Externí odkaz:
https://doaj.org/article/3a58818235844a90999d6fb9d0105171
Autor:
Xuewei Bai, Xiaoqun Dong, Nader Maarouf, Hossein A. Ghanbari, Hikaru Hayashi, Bo Zhai, Rolf I. Carlson, Songhua Zhang, Jack R. Wands, Aryanna Sousa, Yoshihiro Matsumoto, Yuki Yokota, Yanmei Zhou, Bei Sun
Background Interactions between tumor and microenvironment determine individual response to immunotherapy. Triple negative breast cancer (TNBC) and hepatocellular carcinoma (HCC) have exhibited suboptimal responses to immune checkpoint inhibitors (IC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dfdb5e933a8b019dc392a22ce22ef33
https://doi.org/10.21203/rs.3.rs-966722/v1
https://doi.org/10.21203/rs.3.rs-966722/v1
Autor:
Alfred Morgenstern, Ekaterina Dadachova, Muctarr A. Sesay, Susan Walker, Ekaterina Revskaya, Zewei Jiang, Michael S. Lebowitz, Claudia Gravekamp, Steven Fuller, Hossein A. Ghanbari, Frank Bruchertseifer
Publikováno v:
Cancer Biotherapy and Radiopharmaceuticals. 32:57-65
There is a need for novel effective and safe therapies for metastatic breast cancer based on targeting tumor-specific molecular markers of cancer. Human aspartyl (asparaginyl) β-hydroxylase (HAAH) is a highly conserved enzyme that hydroxylates epide
Autor:
Songhua Zhang, Jack R. Wands, Steve Fuller, Zhi-Gang Jiang, Katsuya Nagaoka, Xuewei Bai, Kosuke Ogawa, Rolf I. Carlson, Hossein A. Ghanbari, Yanmei Zhou, Xiaoqun Dong, Michael S. Lebowitz
Publikováno v:
Cancer Lett
Pancreatic ductal adenocarcinoma (PDAC) is an extremely aggressive malignancy with very limited treatment options. Antibody drug conjugates (ADCs) are promising cytotoxic agents capable of highly selective delivery. Aspartate-β-hydroxylase (ASPH) is
Autor:
Hossein A. Ghanbari, Csiki Ildiko, Steven Fuller, Hong Dai, Michael S. Lebowitz, Kanam Malhotra
Publikováno v:
Cancer Research. 79:1454-1454
SNS-301 is a first-in-class immunotherapeutic cancer vaccine candidate targeting human aspartate β-hydroxylase (ASPH). ASPH is an oncofetal antigen expressed in multiple human cancers but not in healthy adult tissue. As a biologic modifier of the NO
Publikováno v:
International Journal of Molecular Sciences, Vol 14, Iss 12, Pp 24438-24475 (2013)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Living cells continually generate reactive oxygen species (ROS) through the respiratory chain during energetic metabolism. ROS at low or moderate concentration can play important physiological roles. However, an excessive amount of ROS under oxidativ
Autor:
Michael S. Lebowitz, Amir H. Shahlaee, Maria R. Baer, Hossein A. Ghanbari, Kanam Malhotra, Ashkan Emadi, Søren M. Bentzen, Noa G. Holtzman, Steven Fuller, Rima Koka
Publikováno v:
Blood. 132:5273-5273
Introduction Despite recent advances in treatment, acute myeloid leukemia (AML) remains difficult to cure with high rates of relapse. Relapsed/refractory AML patients who are elderly or unfit for cytotoxic chemotherapy and whose disease fails to resp
Autor:
Steven Fuller, Michael S. Lebowitz, Susan Walker, Hossein A. Ghanbari, Solomon Stewart, Wu Samindhi M
Publikováno v:
Journal for Immunotherapy of Cancer
Meeting abstracts We are evaluating the immunogenicity and efficacy of a nanoparticle vaccine (NPV) targeting the tumor marker human aspartyl (asparaginyl) β-hydroxylase (HAAH). HAAH is an embryonic protein that is over-expressed on the surface of c
Autor:
Scott A. Burton, Susan Walker, Leonard Y. Chu, Steven Fuller, Allan Bohlke, Michael S. Lebowitz, Vinh Hua, Solomon Stewart, Hossein A. Ghanbari
Publikováno v:
Journal for Immunotherapy of Cancer
Meeting abstracts We are evaluating the immunogenicity and efficacy of a nanoparticle vaccine (NPV) targeting the tumor marker human aspartyl (asparaginyl) β-hydroxylase (HAAH). HAAH is an embryonic protein that is over-expressed on the surface of c