Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Hossam Taha Mohamed"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Externí odkaz:
https://doaj.org/article/29f0db152f5d4c1987dc7ebe338611e0
Autor:
Moustafa A. Shehata, Julia Contreras, Ana Martín-Hurtado, Aurane Froux, Hossam Taha Mohamed, Ahmed A. El-Sherif, Iván Plaza-Menacho
Publikováno v:
Journal of Advanced Research, Vol 45, Iss , Pp 87-100 (2023)
Introduction: The structural and dynamic determinants that confer highly selective RET kinase inhibition are poorly understood. Objectives: To explore the druggability landscape of the RET active site in order to uncover structural and dynamic vulner
Externí odkaz:
https://doaj.org/article/d73b9c202cad4a79b9b5599713b355d1
Autor:
Ashraf S. A. El-Sayed, Amgad M. Rady, Hossam Taha Mohamed, Nabila Zein, Marwa A. Yassin, Nabil Z. Mohamed, Abdallah Hassan, Mahmoud M. Amer, Reyad El-Sharakawy, Aya Ali El-Sharkawy, Nesma El-Sayed, Mostafa G. Ali
Publikováno v:
BMC Microbiology, Vol 23, Iss 1, Pp 1-20 (2023)
Abstract Cytosine deaminase (CDA) is a prodrug mediating enzyme converting 5-flurocytosine into 5-flurouracil with profound broad-range anticancer activity towards various cell lines. Availability, molecular stability, and catalytic efficiency are th
Externí odkaz:
https://doaj.org/article/875cbb935689490ab621e736a5bae482
Autor:
Hossam Taha Mohamed, Aya Ali El-Sharkawy, Mohamed El-Shinawi, Robert J. Schneider, Mona Mostafa Mohamed
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Inflammatory breast cancer (IBC) is a highly aggressive phenotype of breast cancer that is characterized by a high incidence early metastasis. We previously reported a significant association of human cytomegalovirus (HCMV) DNA in the carcinoma tissu
Externí odkaz:
https://doaj.org/article/b2078dcde1ef419297cc014d37236cbd
Autor:
Stéphane Brézillon, Valérie Untereiner, Hossam Taha Mohamed, Estelle Ahallal, Isabelle Proult, Pierre Nizet, Camille Boulagnon-Rombi, Ganesh. D. Sockalingum
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Melanoma is the most aggressive type of cutaneous malignancies. In addition to its role as a regulator of extracellular matrix (ECM) integrity, lumican, a small leucine-rich proteoglycan, also exhibits anti-tumor properties in melanoma. This work foc
Externí odkaz:
https://doaj.org/article/55733cfea8714dabb7280ab4b20104c0
Autor:
Hossam Taha Mohamed, Valérie Untereiner, Gianfelice Cinque, Sherif Abdelaziz Ibrahim, Martin Götte, Nguyet Que Nguyen, Romain Rivet, Ganesh D. Sockalingum, Stéphane Brézillon
Publikováno v:
Molecules, Vol 25, Iss 18, p 4300 (2020)
Glycosaminoglycans (GAGs)/proteoglycans (PGs) play a pivotal role in the metastasis of inflammatory breast cancer (IBC). They represent biomarkers and targets in diagnosis and treatment of different cancers including breast cancer. Thus, GAGs/PGs cou
Externí odkaz:
https://doaj.org/article/c6051622731247e5bb075077466cab33
Publikováno v:
Tumor Biology, Vol 39 (2017)
Interleukin-10 is involved in carcinogenesis by supporting tumor escape from the immune response. The aim of this study was to assess the single nucleotide polymorphisms, −1082A/G, −819T/C and −592A/C, in interleukin-10 gene promoter in inflamm
Externí odkaz:
https://doaj.org/article/86ea8ed98e3d41669feba2a78d07fd77
Autor:
Hossam Taha Mohamed, Mohamed eEl-Shinawi, M. Akram Nouh, Elsayed Tarek Elsayed, Abdel-Rahman eBashtar, Robert J. Schneider, Mona Mostafa Mohamed
Publikováno v:
Frontiers in Oncology, Vol 4 (2014)
Inflammatory breast cancer (IBC) is highly metastatic, aggressive and fatal form of breast cancer. Patients presenting with IBC are characterized by a high number of axillary lymph node metastases. Recently, we found that IBC carcinoma tissues contai
Externí odkaz:
https://doaj.org/article/9db69a20155a48278599483cce353c30
Human cytomegalovirus infection enhances NF-κB/p65 signaling in inflammatory breast cancer patients.
Autor:
Mohamed El-Shinawi, Hossam Taha Mohamed, Eslam A El-Ghonaimy, Marwa Tantawy, Amal Younis, Robert J Schneider, Mona Mostafa Mohamed
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e55755 (2013)
Human Cytomegalovirus (HCMV) is an endemic herpes virus that re-emerges in cancer patients enhancing oncogenic potential. Recent studies have shown that HCMV infection is associated with certain types of cancer morbidity such as glioblastoma. Althoug
Externí odkaz:
https://doaj.org/article/3c63bc66c1154b6a9decaef219669ef1
Autor:
Alshaimaa Tarek, Hossam Taha Mohamed, Aya Ali El-Sharkawy, Shrouk Khalaf El-Sayed, Jon Mark Hirshon, Wendy A Woodward, Mohamed El-Shinawi, Mona Mostafa Mohamed
Publikováno v:
QJM : monthly journal of the Association of Physicians.
Summary Background Matricellular proteins comprising matrisome and adhesome are responsible for structure integrity and interactions between cells in the tumour microenvironment of breast cancer. Changes in the gene expression of matrisome and adheso