Zobrazeno 1 - 10 of 95 pro vyhledávání: '"Hossam, Murad"'
1
Akademický článek
Polymeric nanoparticles loaded with vincristine and carbon dots for hepatocellular carcinoma therapy and imaging
Autor: Walaa Fawaz, Abdulsamie Hanano, Hossam Murad, Amal Yousfan, Ibrahim Alghoraibi, Jameela Hasian
Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Chemotherapy for hepatoblastoma is limited by organ toxicity and poor outcomes, prompting the search for new, more effective treatments with minimal side effects. Vincristine sulfate, a potent chemotherapeutic, faces challenges due to P-glyc
Externí odkaz: https://doaj.org/article/7b25966927fd4f3383da1be4656f9c09
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2
Akademický článek
'In House' assays for the quantification of Annexin V and its autoantibodies in patients with recurrent pregnancy loss and in vitro fertilisation failures
Autor: Hossam Murad, Bouthina Ali, Aya Twair, Khaled Baghdadi, Marwan Alhalabi, Abdul Qader Abbady
Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Several studies have been shown that Annexin V (ANXV) autoantibodies concentrations are associated with both early recurrent pregnancy losses (RPLs) or in vitro fertilization failure (IVFf). We investigated the association between ANXV autoa
Externí odkaz: https://doaj.org/article/86bf951dd13c4e6394d8468dc2903c4b
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3
Akademický článek
Investigation of role of CpG methylation in some epithelial mesenchymal transition gene in a chemoresistant ovarian cancer cell line
Autor: Yaman Alghamian, Chadi Soukkarieh, Abdul Qader Abbady, Hossam Murad
Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Ovarian cancer is one of the lethal gynecologic cancers. Chemoresistance is an essential reason for treatment failure and high mortality. Emerging evidence connects epithelial-mesenchymal transition (EMT) like changes and acquisition of chem
Externí odkaz: https://doaj.org/article/c65a07cbd1254820bbb9c94e35ea296d
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4
Akademický článek
Molecular analysis of the AGXT gene in Syrian patients suspected with primary hyperoxaluria type 1
Autor: Hossam Murad, Mohamad Baseel Alhalabi, Amir Dabboul, Nour Alfakseh, Mohamad Sayah Nweder, Youssef Zghib, Hala Wannous
Publikováno v: BMC Medical Genomics, Vol 14, Iss 1, Pp 1-11 (2021)
Abstract Background Characterization of the molecular basis of primary hyperoxaluria type 1 (PH-1) in Syria has been accomplished through the analysis of 90 unrelated chromosomes from 45 Syrians patients with PH-1 from different regions. Methods Alan
Externí odkaz: https://doaj.org/article/ba8ed58a920f426d862534e29768b23b
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5
Akademický článek
Hb Knossos (HBB: c.82G > T), β-globin CD 5 (−CT) (HBB: c.17_18delCT) and δ-globin CD 59 (−a) (HBD: c.179delA) mutations in a Syrian patient with β-thalassemia intermedia
Autor: Faten Moassas, Mohamad Sayah Nweder, Hossam Murad
Publikováno v: BMC Pediatrics, Vol 19, Iss 1, Pp 1-5 (2019)
Abstract Background Beta thalassemia (β-thal) is an inherited hemoglobin disorder characterized by reduced synthesis of the hemoglobin that results in microcytic hypochromic anemia. β-Thalassemia intermedia (TI) is a clinical term of intermediate g
Externí odkaz: https://doaj.org/article/16742a074f1049bdbcc465d290a3dc9a
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6
Akademický článek
A rare gene variation cap +1 (A>C) (HBB: c. −50A>C) associated with codon 5 (‐CT) (HBB: c.17_18delCT) mutation in Syrian family
Autor: Hossam Murad, Faten Moassas, Nour A. L. Fakseh
Publikováno v: Molecular Genetics & Genomic Medicine, Vol 9, Iss 3, Pp n/a-n/a (2021)
ABSTRACT Background CAP+1 [A>C] (HBB:c.‐50A>C) is a rare silent β‐thalassemia (β‐thal) mutation. Carrier individuals of this mutation show borderline hemoglobin (Hb), mean corpuscular volume (MCV) and Hb A2 levels. This mutation was previousl
Externí odkaz: https://doaj.org/article/7296232119ce4a52aa7cb0f5567df1d3
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7
Akademický článek
أثر مشتقات البلاتين على حيوية الخطين الخلويين MDA-MB-231 وMCF7 المشتقين من سرطان الثدي ودور نواقل ABC والخلايا الجذعية السرطانية في المقاومة
Autor: Chadi Soukkarieh, Hossam Murad, Yaman Alghamian
Publikováno v: مجلة جامعة تشرين للدراسات والبحوث العلمية، سلسلة العلوم الصحية, Vol 42, Iss 6 (2021)
تعد سرطانات الثدي السبب الرئيسي للوفاة لدى النساء وتتصف بكونها غير المتجانسة على المستوى الجزيئي وفي قابلية استجابتها للعلاج الكيميائي.
Externí odkaz: https://doaj.org/article/7b798a3919ac49a78cb5e3aff8fcf8f6
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9
Akademický článek
HLA-DQ2 and -DQ8 genotype frequency in Syrian celiac disease children: HLA-DQ relative risks evaluation
Autor: Hossam Murad, Batoul Jazairi, Issam Khansaa, Doaa Olabi, Lina Khouri
Publikováno v: BMC Gastroenterology, Vol 18, Iss 1, Pp 1-4 (2018)
Abstract Background Celiac disease (CD) is a common autoimmune disease in Syria which manifesting with inflammation of the small intestine and with various extra intestinal symptoms. The disease is associated with human HLA-DQ genes encoding HLA-DQ2
Externí odkaz: https://doaj.org/article/2d7afcf873c140b1a4ac0e547c293e80
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10
Akademický článek
Effects of ionizing radiation on the viability and proliferative behavior of the human glioblastoma T98G cell line
Autor: Hossam Murad, Yaman Alghamian, Abdulmunim Aljapawe, Ammar Madania
Publikováno v: BMC Research Notes, Vol 11, Iss 1, Pp 1-6 (2018)
Abstract Objective Radiotherapy is the traditional therapy for glioma patients. Glioma has poor response to ionizing radiation (IR). Studying radiation-induced cell death can help in understanding the cellular mechanisms underlying its radioresistanc
Externí odkaz: https://doaj.org/article/c31d2a8e71ba4f899990489b1a9015f5
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