Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Hossain, Jahansouz"'
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 33:955-961
An investigational drug (A) in its calcium salt form has been developed as the tablet dosage form. Monitoring drug distribution and uniformity in granules and tablets during early stage formulation/process development is critical for drug product qua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa9ea2f84fde978fe550ec852cb620cd
https://doi.org/10.1016/s0731-7085(03)00364-9
https://doi.org/10.1016/s0731-7085(03)00364-9
Publikováno v:
Chirality. 14:180-186
Nonhomoannular cisoid conjugated dienes exhibit negative lowest-energy π→π* Cotton effects when they have P diene chirality and positive CEs when they have M diene chirality. We investigated this relationship further with a variety of such dienes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33f4dcc04a25487f94cebf38fc698a7d
https://doi.org/10.1002/chir.10067
https://doi.org/10.1002/chir.10067
Autor:
Harold G. Selnick, Nigel J. Liverton, David A. Claremon, Melanie S. Houle, David B. Gilberto, Andrew J. Tebben, Audrey A. Wallace, Smith Garry R, George E. Billman, Hossain Jahansouz, Gary L. Stump, Joseph J. Lynch
Publikováno v:
Circulation. 100:1917-1922
Background —To date, the lack of potent and selective inhibitors has hampered the physiological assessment of modulation of the cardiac slowly activating delayed rectifier current, I Ks . The present study, using the I Ks blocker L-768,673, represe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4358e5390bc3c9af6d728a1be950123
https://doi.org/10.1161/01.cir.100.18.1917
https://doi.org/10.1161/01.cir.100.18.1917
Publikováno v:
Pharmaceutical Development and Technology. 4:81-87
The objective of this work was to compare the physicochemical properties of four crystalline forms of the fibrinogen receptor antagonist L-738,167 [2(S)-[p-toluenesulfonyl amino]-3-[[[5,6,7,8-tetrahydro-4-oxo-5-[2-(piperidin-4-yl)ethyl] -4-H-pyrazolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a48b8a4d2f9473c86fd82804865541a9
https://doi.org/10.1080/10837459908984227
https://doi.org/10.1080/10837459908984227
Publikováno v:
Pharmaceutical Development and Technology. 4:181-187
The polymorphism of the angiotensin II antagonist agent MK-996 was studied, with particular emphasis on crystal form stability, solubility, and reproducible crystallization of the drug. X-ray powder diffraction patterns indicated differences in the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee6c50df9d04e6c57e1abd28934fc26d
https://doi.org/10.1081/pdt-100101352
https://doi.org/10.1081/pdt-100101352
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 17:679-687
A sensitive and specific method based on solid-phase extraction and reverse-phase liquid chromatography was developed and validated for the quantitation of L-768 673 in a microemulsion formulation. Following a water wash, the drug was eluted from the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b581e58b4a6a6843e367ae235d05c54a
https://doi.org/10.1016/s0731-7085(97)00253-7
https://doi.org/10.1016/s0731-7085(97)00253-7
Publikováno v:
Drug Development and Industrial Pharmacy. 22:873-880
The physicochemical properties of the novel antiarrhythmic agent L-691, 121 [methanesulfonamide, N- (1′- (2- (5-benzofirazanyl)ethyl)-3, 4-dihydro-4-oxospiro(2H-1-benzopyran-2, 4′-piperdin)6-yl), hydrochloride] have been studied, with particular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88f46ef7fe8fa5bd8fa127e707c379f1
https://doi.org/10.3109/03639049609065917
https://doi.org/10.3109/03639049609065917
Autor:
Joseph J. Salata, David A. Claremon, Andrew J. Tebben, Garry R. Smith, Harold G. Selnick, Gary L. Stump, Hossain Jahansouz, Joseph J. Lynch
Publikováno v:
Journal of cardiovascular pharmacology. 42(1)
Previous cardiac electrophysiologic studies of blockers of the slowly activating delayed rectifier (I Ks ) current have focused primarily on ventricular repolarization. This report summarizes an extensive in vivo cardiac electrophysiologic profile of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2bb3518b0d9711e80084f70c703a338
https://pubmed.ncbi.nlm.nih.gov/12827034
https://pubmed.ncbi.nlm.nih.gov/12827034
Publikováno v:
Chirality. 14(2-3)
Nonhomoannular cisoid conjugated dienes exhibit negative lowest energy pi--pi* Cotton effects when they have P diene chirality and positive CEs when they have M diene chirality. We investigated this relationship further with a variety of such dienes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::33e2e39bd02dbc59b5954e87fc322c8d
https://pubmed.ncbi.nlm.nih.gov/11835563
https://pubmed.ncbi.nlm.nih.gov/11835563
Autor:
Nobuo Harada, Daniela Gorbacheva, Kimimasa Suzuki, Kiyofumi Ishikawa, Michelle L. Bray, Hossain Jahansouz, Michael J. Kaufman
Publikováno v:
Chemicalpharmaceutical bulletin. 49(1)
The degradation of [5S-[5alpha,6beta,7alpha(R*)]]-2-butyl-5-(1,3-benzodioxol-5-yl)-7-[(2-carboxypropyl)-4-methoxyphenyl]-6-dihydro-5H-cyclopenta[b]pyridine-6-carboxylic acid (J-104,132) was studied in aqueous solution as a function of temperature and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81d11f6f10bb4164abea258a3c15165f
https://pubmed.ncbi.nlm.nih.gov/11201209
https://pubmed.ncbi.nlm.nih.gov/11201209