Viral recombination systems limit CRISPR-Cas targeting through the generation of escape mutations

Autor: Hossain, Amer A., McGinn, Jon, Meeske, Alexander J., Modell, Joshua W., Marraffini, Luciano A.

Publikováno v: In Cell Host & Microbe 13 October 2021 29(10):1482-1495

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Mammalian target of rapamycin pathway mutations cause hemimegalencephaly and focal cortical dysplasia

Autor: D'Gama, Alissa M, Geng, Ying, Couto, Javier A, Martin, Beth, Boyle, Evan A, LaCoursiere, Christopher M, Hossain, Amer, Hatem, Nicole E, Barry, Brenda J, Kwiatkowski, David J, Vinters, Harry V, Barkovich, A James, Shendure, Jay, Mathern, Gary W, Walsh, Christopher A, Poduri, Annapurna

Publikováno v: D'Gama, AM; Geng, Y; Couto, JA; Martin, B; Boyle, EA; Lacoursiere, CM; et al.(2015). Mammalian target of rapamycin pathway mutations cause hemimegalencephaly and focal cortical dysplasia. Annals of Neurology. doi: 10.1002/ana.24357. UCSF: Retrieved from: http://www.escholarship.org/uc/item/6ts4k6c2
Annals of Neurology, vol 77, iss 4
Annals of neurology, vol 77, iss 4
D'Gama, AM; Geng, Y; Couto, JA; Martin, B; Boyle, EA; Lacoursiere, CM; et al.(2015). Mammalian target of rapamycin pathway mutations cause hemimegalencephaly and focal cortical dysplasia. Annals of Neurology, 77(4), 720-725. doi: 10.1002/ana.24357. UCLA: Retrieved from: http://www.escholarship.org/uc/item/7p37s95b

© 2015 American Neurological Association. Focal malformations of cortical development, including focal cortical dysplasia (FCD) and hemimegalencephaly (HME), are important causes of intractable childhood epilepsy. Using targeted and exome sequencing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::09c17b8cb5799da96b7bf337201884f2
http://www.escholarship.org/uc/item/6ts4k6c2

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.