Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Hoshang Patel"'
Autor:
Krishnarup Ghoshdastidar, Hoshang Patel, Hitesh Bhayani, Ankit Patel, Kinjal Thakkar, Dinesh Patel, Manoranjan Sharma, Jaideep Singh, Jogeswar Mohapatra, Abhijit Chatterjee, Dipam Patel, Rajesh Bahekar, Rajiv Sharma, Lakshmikant Gupta, Nirmal Patel, Poonam Giri, Nuggehally R. Srinivas, Mukul Jain, Debdutta Bandyopadhyay, Pankaj R. Patel, Ranjit C. Desai
Publikováno v:
Pharmacology Research & Perspectives, Vol 8, Iss 4, Pp n/a-n/a (2020)
Abstract Bruton's tyrosine kinase (BTK) plays a central and pivotal role in controlling the pathways involved in the pathobiology of cancer, rheumatoid arthritis (RA), and other autoimmune disorders. ZYBT1 is a potent, irreversible, specific BTK inhi
Externí odkaz:
https://doaj.org/article/426ccabb23744fc0aceb0a7d29b505f0
Autor:
Darshan Joshi, Rajesh Bahekar, Shubhangi Soman, Pradip Jadav, Dipam Patel, Amitgiri Goswami, Jignesh Pethani, Jeevan Kumar, Jitendra Patel, Rajesh Sundar, Poonamgiri Goswami, Krishnarup Goshdastidar, Hoshang Patel, Ankit Patel, Debdutta Bandyopadhyay, Abhijit Chattarjee, Manoranjan Sharma, Mukul Jain, Ranjit Desai
Publikováno v:
Bioorganic chemistry. 130
To discover the best-in-class Bruton's Tyrosine Kinase (BTK) inhibitors, for th treatment of autoimmune disorders like cancer (B-Cell Lymphoma (BCL)) and rheumatoid arthritis (RA), in the present investigation, novel structural optimizations were car
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef4f6b580e492454dbe243bc5a720bf4
https://pubmed.ncbi.nlm.nih.gov/36403335
https://pubmed.ncbi.nlm.nih.gov/36403335
Autor:
Jigar N. Desai, Bhaumin Patel, Archana Gite, Nandini Panchal, Sanjay Gite, Anil Argade, Jeevan Kumar, Sachchidanand s, Debdutta Bandyopadhyay, KRISHNARUP DASTIDAR, Hoshang Patel, Abhijit Chatterjee, Jogeshwar Mahapatra, Manoranjan Sharma, Poonam Giri, Sanjay Kumar, Mukul Jain, Rajiv Sharma, Ranjit Desai
Publikováno v:
Bioorganicmedicinal chemistry letters. 66
Dysregulated JAK-STAT signaling has been proven to be involved in several immune-mediated diseases. Several janus kinase (JAK) inhibitors have been approved for the treatment of various inflammatory and autoimmune diseases such as rheumatoid arthriti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::562f5c0d97c9943bcf89352c107b020c
https://pubmed.ncbi.nlm.nih.gov/35413417
https://pubmed.ncbi.nlm.nih.gov/35413417
Autor:
Dinesh Patel, Dipam Patel, Pankaj R. Patel, Jogeswar Mohapatra, Hoshang Patel, Krishnarup Ghoshdastidar, Abhijit Chatterjee, Rajiv P. Sharma, Mukul R. Jain, Jaideep Singh, Manoranjan Sharma, Poonam Giri, Kinjal Thakkar, Debdutta Bandyopadhyay, Rajesh Bahekar, Hitesh Bhayani, Ranjit C. Desai, Ankit Patel, Lakshmikant Gupta, Nuggehally R. Srinivas, Nirmal Patel
Publikováno v:
Pharmacology Research & Perspectives, Vol 8, Iss 4, Pp n/a-n/a (2020)
Pharmacology Research & Perspectives
Pharmacology Research & Perspectives
Bruton's tyrosine kinase (BTK) plays a central and pivotal role in controlling the pathways involved in the pathobiology of cancer, rheumatoid arthritis (RA), and other autoimmune disorders. ZYBT1 is a potent, irreversible, specific BTK inhibitor tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e4e4ffa841ea0712306327b9f3c7fca
https://doaj.org/article/426ccabb23744fc0aceb0a7d29b505f0
https://doaj.org/article/426ccabb23744fc0aceb0a7d29b505f0
Autor:
Akshyaya Rath, Baban Thube, Shailesh R. Shah, Suresh Pola, Harilal Patel, Hoshang Patel, Pandurang Zaware, Jeevan Kumar, Harikishore Pingali, Mukul R. Jain, S.R. Sundar, Pankaj Makadia, Jitendra Patel, Suresh Giri, Debdutta Bandyopadhyay, Ramchandra Ranvir
Publikováno v:
Bioorganic & Medicinal Chemistry. 35:116071
The ever-growing prevalence of Type-2 diabetes in the world has an urgent need for multiple orally effective agents that can regulate glucose homeostasis. G-Protein coupled receptor 119 (GPR 119) agonists have demonstrated the glucose-dependent insul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::072c8cd4e0ffd09af118806aee19811d
https://doi.org/10.1016/j.bmc.2021.116071
https://doi.org/10.1016/j.bmc.2021.116071
Autor:
Debdutta Bandyopadhyay, Jigar Desai, Abhijit Chatterjee, Hoshang Patel, S. Sachchidanand, Rajesh Bahekar, Jeevan Kumar, Dipam Patel, Krishnarup Ghoshdastidar, Anil Argade, Harilal Patel, Archana Gite, Bhaumin Patel, Sanjay Gite, Jogeswar Mahapatra, Nandini Panchal, Rajesh Sundar, Ranjit C. Desai, Shubhangi S. Soman
Publikováno v:
Bioorganic Chemistry. 99:103851
Selective inhibition of janus kinase (JAK) has been identified as an important strategy for the treatment of autoimmune disorders. Optimization at the C2 and C4-positions of pyrimidine ring of Cerdulatinib led to the discovery of a potent and orally
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f57c25ee9d80ecff1fec355cd350348
https://doi.org/10.1016/j.bioorg.2020.103851
https://doi.org/10.1016/j.bioorg.2020.103851