Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Hosea Akala"'
Autor:
Gladys C. Chemwor, Ben Andagalu, Jennifer M. Mutisya, Johnson Kinyua, Amanda L. Roth, Jackline A. Juma, Hosea Akala, Dennis W. Juma, Martha N. Kivecu, Charles O. Okello, Redempta A. Yeda, Victor A. Mobegi, Raphael Okoth, Edwin W. Mwakio, Benjamin Opot, Agnes C. Cheruiyot
Publikováno v:
F1000Research. 9:1268
Background: The emergence of artemisinin resistance in South East Asia calls for urgent discovery of new drug compounds that have antiplasmodial activity. Unlike the classical compound screening drug discovery methods, the rational approach involving
Autor:
Pauline N. M. Mwinzi, Sylvia A. Opiyo, Lawrence A.O. Manguro, Angeline Atieno Ochung, Hosea Akala, Isaac O. Jondiko, Regina Nyunja, Phillip Okinda Owuor
Publikováno v:
Journal of the Korean Society for Applied Biological Chemistry. 58:839-846
Phytochemical and biological evaluation of the stem bark of Alysicarpus ovalifolius led to the isolation of three carbazole alkaloids identified as mohanimbine (1), koenimbine (2) and koenidine (3) along with quercetin 3-O-glucoside (4), kaempferol 7
Autor:
Ahmed Hassanali, J.W. Gathirwa, Hosea Akala, Hamisi M. Malebo, Alex K. Machocho, Ruth Anyango Omole, Isaiah O. Ndiege
Publikováno v:
Phytochemistry. 103:123-128
Two bisbenzylisoquinoline and one hasubanane alkaloids: (-)-pseudocurine (1), (-)-pseudoisocurine (2) and (-)-10-oxoaknadinine (3), were isolated from leaf extract of Stephania abyssinica, a plant used in traditional medicine in South Nyanza region o
Publikováno v:
Fitoterapia. 83:74-80
The chloroform and ethyl acetate extract (100 mg/kg) of Caesalpinia volkensii H. exhibited significant (P ≤ 0.05) antinociceptive activities using hot plate and writhing tests in mice while the later showed antiplasmodial activity (IC50 0.23 ± 0.0
Autor:
Fidilia M. Omoto, Pamela Liyala, Julia Wangui, Hosea Akala, Abiy Yenesew, Norman C. Waters, Jacob O. Midiwo, Christine Wasunna
Publikováno v:
ARKIVOC, Vol 2007, Iss 9, Pp 21-27 (2006)
Phytochemical re-examination of the aerial exudates of Polygonum senegalense forma senegalense has resulted in the isolation and characterization of a novel homoisoflavonoid, 5,7- dihydroxy-3-(hydroxy-phenyl-methyl)-6-methoxy-chroman-4-one (trivial n
Autor:
Pamela Liyala, R R T Majinda, A O Abosl, Jacob O. Midiwo, B H Raserok, Hosea Akala, Abiy Yenesew, Norman C. Waters, E Mbukwa
Publikováno v:
British Journal of Biomedical Science. 63:129-133
Vangueria infausta burch subsp. infausta (Rubiaceae) produces fruits eaten by humans and animals. The leaf, fruit, stem bark and root bark are used as a remedy for many ailments and the roots are used to treat malaria. In this study, concentrations o
Autor:
Matthias Heydenreich, Martin G. Peter, Hellen A. Oketch-Rabah, Abiy Yenesew, Julia Wangui, Jacob O. Midiwo, Rex A. Palmer, Norman C. Waters, J. N. Lisgarten, Solomon Derese, Pamela Liyala, Hosea Akala
Publikováno v:
Phytochemistry. 64:773-779
The dichloromethane extract of the stem bark of Millettia usaramensis subspecies usaramensis showed anti-plasmodial activity against the chloroquine sensitive (D6) and chloroquine resistant (W2) strains of Plasmodium falciparum. Chromatographic separ
Autor:
Ogoche J. I. Jondiko, Peter M. Gitu, Julia Wangui, Jacob O. Midiwo, Pamela Liyala, Andrew W. Andayi, Matthias Heydenreich, Abiy Yenesew, Solomon Derese, Norman C. Waters, Hosea Akala, Martin G. Peter
Publikováno v:
Planta Medica. 72:187-189
The acetone extracts of the root bark and stem bark of Erythrina sacleuxii showed antiplasmodial activities against the chloroquine-sensitive (D6) and chloroquine-resistant (W2) strains of Plasmodium falciparum. Chromatographic separation of the acet
Publikováno v:
ChemInform. 44
Three new cassane diterpenes, voulkensin C (Ia), D (Ib), and E (II), and a new steroidal-stigmasterol glycoside (III) are isolated together with seven known compounds.
Publikováno v:
Bioorganicmedicinal chemistry letters. 23(10)
A bioassay guided isolation of potential antimalarial molecules from the stem bark of Caesalpinia volkensii Harms (Fabaceae) achieved three new 11-oxocassane-type diterpenoids named voulkensin C (1), D (2) and E (3) together with one steroid glycosid