Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Hosam Choi"'
Publikováno v:
Molecules, Vol 29, Iss 3, p 701 (2024)
In this study, the divergent syntheses of (-)-chicanine, (+)-fragransin A2, (+)-galbelgin, (+)-talaumidin, and (+)-galbacin are detailed. In this approach, an early-stage modified Kowalski one-carbon homologation reaction is utilized to construct the
Externí odkaz:
https://doaj.org/article/c6df1508c2564aee8b5e7531c6449bf5
Publikováno v:
Molecules, Vol 26, Iss 3, p 597 (2021)
Herein, we are reporting an efficient approach toward the synthesis of 4,5-disubstituted oxazolidin-2-one scaffolds. The developed approach is based on a combination of an asymmetric aldol and a modified Curtius protocol, which uses an effective intr
Externí odkaz:
https://doaj.org/article/2a11fd86154d421b89d8ecc39e38a83f
Publikováno v:
Organic Letters. 24:9238-9242
In this report, we present a highly efficient approach for the synthesis of β,γ-disubstituted γ-butyrolactone motifs. This newly developed strategy is based on the combination of a diastereoselective aldol and a nickel carbene-mediated γ-butyrola
Publikováno v:
The Journal of Organic Chemistry. 87:4316-4322
A seven-step asymmetric total synthesis of gymnothelignan N is detailed in the current report. The approach is based on an early-stage one-carbon homologative lactonization reaction, which we recently revisited and modified to construct the core γ-b
Publikováno v:
Organic letters. 24(15)
The first total synthesis of tetrahydrofuran dilignan gymnothelignan K is disclosed. The approach is based on implementing an early stage one-carbon homologative lactonization, which we recently disclosed, for constructing the γ-butyrolactone scaffo
Publikováno v:
European Journal of Organic Chemistry. 2020:689-692
Autor:
Hyo Won Lee, Hosam Choi, Kiyoun Lee, Sung Jae Shin, Hwan Myung Kim, Chang Su Lim, Myoung Ki Cho, Choong-Kyun Noh
Publikováno v:
Analytical Chemistry. 91:14705-14711
Colorectal cancer is a major cause of cancer-related deaths worldwide. Histologic diagnosis using biopsy samples of colorectal neoplasms is the most important step in determining the treatment methods, but these methods have limitations in accuracy a
Publikováno v:
Organic Letters. 21:7857-7862
A highly efficient synthesis of functionalized chiral γ-butyrolactone scaffolds has been described. The basis of the approach is the Kowalski ester homologation that is modified for our proposed tr...
Publikováno v:
Molecules, Vol 26, Iss 597, p 597 (2021)
Molecules
Volume 26
Issue 3
Molecules
Volume 26
Issue 3
Herein, we are reporting an efficient approach toward the synthesis of 4,5-disubstituted oxazolidin-2-one scaffolds. The developed approach is based on a combination of an asymmetric aldol and a modified Curtius protocol, which uses an effective intr
Publikováno v:
Synlett. 29:1203-1206
A concise total synthesis of (±)-mesembrine has been successfully accomplished in seven steps and 24% overall yield from commercially available 3-ethoxy-2-cyclohexen-1-one. Central to the assembly of the skeleton of mesembrine are a Johnson–Claise