Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Hosadurga K Keerthy"'
Autor:
Hosadurga K Keerthy, Manoj Garg, Chakrabhavi D Mohan, Vikas Madan, Deepika Kanojia, Rangappa Shobith, Shivananju Nanjundaswamy, Daniel J Mason, Andreas Bender, Basappa, Kanchugarakoppal S Rangappa, H Phillip Koeffler
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107118 (2014)
The anti-apoptotic protein Bcl-2 is a well-known and attractive therapeutic target for cancer. In the present study the solution-phase T3P-DMSO mediated efficient synthesis of 2-amino-chromene-3-carbonitriles from alcohols, malanonitrile and phenols
Externí odkaz:
https://doaj.org/article/ec334f3735274b5a85eba3c8c2d4fc77
Autor:
Andreas Bender, Hanumantharayappa Bharathkumar, Fredrick Svensson, Kanchugarakoppal S. Rangappa, Basappa, Chakrabhavi Dhananjaya Mohan, Shobith Rangappa, Surender Mohan, Rakesh Bhatnagar, Hosadurga K. Keerthy
Publikováno v:
Chemistry & Biodiversity. 16
© 2019 Wiley-VHCA AG, Zurich, Switzerland Phosphodiesterase 4 (PDE4) is a key enzyme involved in the hydrolysis of cyclic adenosine monophosphate (cAMP) and widely expressed in several types of cancers. The inhibition of PDE4 results in an increased
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14e79d0a20a52f7e1973dce8f7b716f5
https://doi.org/10.1002/cbdv.201900234
https://doi.org/10.1002/cbdv.201900234
Autor:
Hosadurga K. Keerthy, Kanchugarakoppal S. Rangappa, Nanjuda Swamy S, Lewis H. Mervin, Krishna C. Bulusu, Andreas Bender, H. K. Vivek, Shobith Rangappa, Hanumantharayappa Bharathkumar, Julian E. Fuchs, B. S. Priya, Basappa Basappa
Publikováno v:
RSC Advances. 5:89797-89808
Phospholipase A2 (PLA2) is known to regulate inflammation and hence it is considered as a validated drug-target by medicinal chemists. In this report, we have identified and considered a highly ranked ligand from the ZINC-drug-like compounds database
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15cfd99d5ba29cbeb4e80be53b5d1b9c
https://doi.org/10.1039/c5ra13085a
https://doi.org/10.1039/c5ra13085a
Autor:
Hanumantharayappa Bharathkumar, Shobith Rangappa, Kanchugarakoppal S. Rangappa, Sunghoon Kim, Chakrabhavi Dhananjaya Mohan, Taehee Kang, Basappa, Julian E. Fuchs, Hosadurga K. Keerthy, Nam Hoon Kwon, Andreas Bender
Publikováno v:
Organic & Biomolecular Chemistry. 13:9381-9387
Elevated activity of methionyl-tRNA synthetase (MRS) in many cancers renders it a possible drug target in this disease area, as well as in a series of parasitic diseases. In the present work, we report the synthesis and in vitro screening of a librar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a54544c04d63bf5a1683591ae528a62
https://doi.org/10.1039/c5ob00791g
https://doi.org/10.1039/c5ob00791g
Autor:
Hosadurga K. Keerthy, Basappa, Gautam Sethi, Chakrabhavi Dhananjaya Mohan, Feng Li, Andreas Bender, Kesturu S. Girish, Kodappully Sivaraman Siveen, Shobith Rangappa, Mahalingam S. Sundaram, Julian E. Fuchs, Kanchugarakoppal S. Rangappa
Publikováno v:
The Journal of biological chemistry. 289(46)
TNF is a pleotropic cytokine known to be involved in the progression of several pro-inflammatory disorders. Many therapeutic agents have been designed to counteract the effect of TNF in rheumatoid arthritis as well as a number of cancers. In the pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92fb89c0a327fc017bee1f3494d47440
https://pubmed.ncbi.nlm.nih.gov/25231984
https://pubmed.ncbi.nlm.nih.gov/25231984
Autor:
Rangappa Shobith, Kanchugarakoppal S. Rangappa, H. Phillip Koeffler, Vikas Madan, Andreas Bender, Deepika Kanojia, Basappa, Hosadurga K. Keerthy, Shivananju Nanjunda-Swamy, Chakrabhavi Dhananjaya Mohan, Daniel J. Mason, Manoj Garg
Publikováno v:
PLoS ONE
PloS one, vol 9, iss 9
PLoS ONE, Vol 9, Iss 9, p e107118 (2014)
PloS one, vol 9, iss 9
PLoS ONE, Vol 9, Iss 9, p e107118 (2014)
The anti-apoptotic protein Bcl-2 is a well-known and attractive therapeutic target for cancer. In the present study the solution-phase T3P-DMSO mediated efficient synthesis of 2-amino-chromene-3-carbonitriles from alcohols, malanonitrile and phenols
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3721fd70e21b37ae4e55b3b7c8f3752
https://doi.org/10.1371/journal.pone.0107118
https://doi.org/10.1371/journal.pone.0107118