Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Hortensia G. Rolán"'
Autor:
Kailash P Patra, Mayuko Saito, Vidya L Atluri, Hortensia G Rolán, Briana Young, Tobias Kerrinnes, Henk Smits, Jessica N Ricaldi, Eduardo Gotuzzo, Robert H Gilman, Renee M Tsolis, Joseph M Vinetz
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 8, Iss 6, p e2926 (2014)
Human brucellosis is most commonly diagnosed by serology based on agglutination of fixed Brucella abortus as antigen. Nucleic acid amplification techniques have not proven capable of reproducibly and sensitively demonstrating the presence of Brucella
Externí odkaz:
https://doaj.org/article/78ee8f95f67d4901ac92cf60b38fc0af
Autor:
Jonathan Ferooz, Vidya L. Atluri, Mariana N. Xavier, Gabriel Núñez, Matthieu Terwagne, Luigi Franchi, Richard A. Flavell, Xavier De Bolle, Renée M. Tsolis, Jean-Jacques Letesson, Yao Hui Sun, Thomas Legrand, Hortensia G. Rolán
Publikováno v:
Cellular Microbiology. 15:942-960
Brucella are facultative intracellular bacteria that cause chronic infections by limiting innate immune recognition. It is currently unknown whether Brucella FliC flagellin, the monomeric subunit of flagellar filament, is sensed by the host during in
Publikováno v:
Cellular Microbiology. 12:1195-1202
In humans, pathogenic Brucella species cause a febrile illness known as brucellosis. A key pathogenic trait of this group of organisms is their ability to survive in immune cells and persist in tissues of the reticuloendothelial system, a process tha
Publikováno v:
Cellular Microbiology. 12:988-1001
YopE, a type III secreted effector of Yersinia, is a GTPase Activating Protein for Rac1 and RhoA whose catalytic activity is critical for virulence. We found that YopE also inhibited reactive oxygen species (ROS) production and inactivated Rac2. How
Publikováno v:
Infection and Immunity. 77:3004-3013
Brucella abortus is an intracellular pathogen that persists within phagocytic cells of the reticuloendothelial system. To identify in vivo interactions between B. abortus and the host that lead to persistent infection, we studied the persistence of B
Autor:
Renée M. Tsolis, Hortensia G. Rolán
Publikováno v:
Infection and Immunity. 76:3207-3213
TheBrucella abortustype IV secretion system (T4SS), encoded by thevirBoperon, is essential for establishing persistent infection in the murine reticuloendothelial system. To gain insight into the in vivo interactions mediated by the T4SS, we compared
Autor:
Takeshi Haneda, Renée M. Tsolis, Tatiane A. Paixão, Renato L. Santos, Manuela Raffatellu, Ivan Godinez, Michael D. George, Hortensia G. Rolán, Andreas J. Bäumler, Satya Dandekar
Publikováno v:
Infection and Immunity. 76:2008-2017
Salmonella entericaserotype Typhimurium causes an acute inflammatory reaction in the ceca of streptomycin-pretreated mice. We determined global changes in gene expression elicited by serotype Typhimurium in the cecal mucosa. The gene expression profi
Publikováno v:
Journal of Biological Chemistry. 282:33897-33901
Bacterial flagellins are potent inducers of innate immunity. Three signaling pathways have been implicated in the sensing of flagellins; these involve toll-like receptor 5 (TLR5) and the cytosolic proteins Birc1e/Naip5 and Ipaf. Although the structur
Autor:
Renée M. Tsolis, Hortensia G. Rolán
Publikováno v:
Infection and Immunity. 75:2965-2973
The Brucella abortus type IV secretion system (T4SS), encoded by the virB genes, is essential for survival in mononuclear phagocytes in vitro. In the mouse model, a B. abortus virB mutant was initially able to colonize the spleen at the level of the
Publikováno v:
Infection and Immunity. 73:6048-6054
The Brucella abortus virB operon, consisting of 11 genes, virB1 to virB11 , and two putative genes, orf12 ( virB12 ) and orf13 , encodes a type IV secretion system (T4SS) that is required for intracellular replication and persistent infection in the