Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Hortensia Faus"'
Autor:
Tatsuo Sugawara, Hortensia Faus, Roland Neuhaus, Arwed Cleve, Kathy A. Gelato, Michael Brands, Matthias Busemann, Ulrich Lücking, Bernard Haendler, Dominik Mumberg, Klaus Jung, Pascale Lejeune, Silke Köhr, Franz von Nussbaum, Carsten Stephan
Publikováno v:
Oncotarget
Androgen receptor (AR) mutations arise in patients developing resistance to hormone deprivation therapies. Here we describe BAY 1024767, a thiohydantoin derivative with strong antagonistic activity against nine AR variants with mutations located in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e9cae2fdb9c82c069cd1ab2fc0da8c1
https://pubmed.ncbi.nlm.nih.gov/26760770
https://pubmed.ncbi.nlm.nih.gov/26760770
Autor:
Iduna Fichtner, Bernard Haendler, Hortensia Faus, Anette Sommer, Holger Hess-Stumpp, Tomke Ute Bracker
Publikováno v:
International Journal of Oncology 35 (4): 909-920.
N-(2-aminophenyl)-4-[N-(pyridine-3yl-methoxy-carbonyl) aminomethyl] benzamide (MS-275) is a second generation histone deacetylase (HDAC) inhibitor with significant anti-tumor efficacy currently in clinical development. We investigated the effect of M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb8f4f075764ac1c2bd556f4c77a19ea
http://edoc.mdc-berlin.de/10485/
http://edoc.mdc-berlin.de/10485/
Autor:
Pascale Lejeune, Arwed Cleve, Hortensia Faus, Matthias Busemann, Bernard Haendler, Silke Koehr, Ulrich Luecking, Franz von Nussbaum, Tatsuo Sugawara, Michael Brands, Dominik Mumberg
Publikováno v:
Cancer Research. 73:1321-1321
Analysis of biopsies from prostate cancer metastases and of circulating tumor cells shows that androgen receptor (AR) mutations are often found in patients developing resistance to antiandrogen therapy, i.e. at the castration-resistant prostate cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::173c6b660944f6a974eb610b4f67b17e
https://doi.org/10.1158/1538-7445.am2013-1321
https://doi.org/10.1158/1538-7445.am2013-1321
Publikováno v:
Gene. 399(2)
A cDNA coding for a tissue-specific AR45 variant form of the androgen receptor (AR) has recently been identified in humans, with highest expression levels found in heart. The deduced protein comprises the DNA-binding domain, hinge region and ligand-b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0cee24a59407a988ecced53dea35ce8
https://pubmed.ncbi.nlm.nih.gov/17574777
https://pubmed.ncbi.nlm.nih.gov/17574777
Autor:
Hortensia Faus Gimenèz, Günter Lochnit, Frank Landgraf, Holger M. Strauss, Janina Hahn, Jon Hughes, Peter Schmieder
Publikováno v:
The FEBS journal. 273(7)
We have investigated mutants of phytochrome Cph1 from the cyanobacterium Synechocystis PCC6803 in order to study chromophore-protein interactions. CphlA2, the 514-residue N-terminal sensor module produced as a recombinant His6-tagged apoprotein in Es
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15aecb2b66b4c832874c826350f9e2f7
https://pubmed.ncbi.nlm.nih.gov/16689929
https://pubmed.ncbi.nlm.nih.gov/16689929
Publikováno v:
Molecular and cellular endocrinology. 245(1-2)
The role of the ubiquitin/proteasome system in degrading nuclear hormone receptors and regulating their transcriptional function has emerged in the last few years. We identified the ubiquitin-specific protease USP10 as part of DNA-bound androgen rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b8c23ac26c286cc2b89169cc9578e3a
https://pubmed.ncbi.nlm.nih.gov/16368182
https://pubmed.ncbi.nlm.nih.gov/16368182
Autor:
Hahn, Janina, Strauss, Holger M., Landgraf, Frank T., Gimenèz, Hortensia Faus, Lochnit, Günter, Schmieder, Peter, Hughes, Jon
Publikováno v:
FEBS Journal; Jun2006, Vol. 273 Issue 12, p1415-1429, 15p, 1 Black and White Photograph, 2 Charts, 9 Graphs