Zobrazeno 1 - 10 of 339 pro vyhledávání: '"Horst Will"'
1
Elektronická kniha
Molekularbiologie kurz und bündig
Autor: Horst Will
Dieses Buch fasst den aktuellen Stand der Molekularbiologie kurz und knapp zusammen und gibt Auskunft über grundlegende Lebensprozesse. Die Themen reichen von der Struktur der DNA und ihrer Funktion in der Vererbung bis zur Entwicklung differenziert
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2
The TIMP2 Membrane Type 1 Metalloproteinase 'Receptor' Regulates the Concentration and Efficient Activation of Progelatinase A
Autor: Tatsuya Tamura, Gillian Murphy, John Clements, Thomas Crabbe, Horst Will, Susan J. Atkinson, Georgina S. Butler, Marie-Pia d'Ortho, Michael J. Butler, Steven Schade van Westrum
Publikováno v: Journal of Biological Chemistry. 273:871-880
We have used C-terminal domain mutants to further define the role of interactions of progelatinase A and membrane type 1 matrix metalloproteinase (MT1 MMP) in the binding of TIMP2 and in the cell-associated activation of progelatinase A. Soluble cons
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::12e950cf15f149da6edd383fdd7ca0af
https://doi.org/10.1074/jbc.273.2.871
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8
Cellular Mechanisms for Human Procollagenase-3 (MMP-13) Activation
Autor: Gillian Murphy, Horst Will, Vera Knäuper, Carlos López-Otín, Bryan D. Smith, Susan J. Atkinson, Rosalind M. Hembry, Heather Stanton
Publikováno v: Journal of Biological Chemistry. 271:17124-17131
Gelatinase A and membrane-type metalloproteinase (MT1-MMP) were able to process human procollagenase-3 (Mr 60,000) to the fully active enzyme (Tyr85 N terminus; Mr 48,000). MT1-MMP activated procollagenase-3 via a Mr 56,000 intermediate (Ile36 N term
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::40158e631d0e2c1f70402fcfcbcd383c
https://doi.org/10.1074/jbc.271.29.17124
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9
The Soluble Catalytic Domain of Membrane Type 1 Matrix Metalloproteinase Cleaves the Propeptide of Progelatinase A and Initiates Autoproteolytic Activation
Autor: Bryan D. Smith, Georgina S. Butler, Susan J. Atkinson, Horst Will, Gillian Murphy
Publikováno v: Journal of Biological Chemistry. 271:17119-17123
It has been proposed that the cell-mediated activation of progelatinase A requires binding of the C-terminal domain of the proenzyme to a membrane-associated complex of the membrane type matrix metalloproteinase MT1-MMP and TIMP-2. Subsequent sequent
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::14c4083fc1e1793f6e733bbe9e47d92e
https://doi.org/10.1074/jbc.271.29.17119
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10
cDNA Sequence and mRNA Tissue Distribution of a Novel Human Matrix Metalloproteinase with a Potential Transmembrane Segment
Autor: Bernd Hinzmann, Horst Will
Publikováno v: European Journal of Biochemistry. 231:602-608
The complementary DNA sequence of a novel matrix metalloproteinase was isolated from a human lung cDNA library. It consists of 3530 bp and encodes a polypeptide of 669 amino acids. In comparison to other matrix metalloproteinases, the deduced sequenc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eb98b26a0c3db366de443a998d8b97c
https://doi.org/10.1111/j.1432-1033.1995.0602d.x
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