Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Horst Ruppach"'
Autor:
Simon Gustafsson, Frank Westermann, Tobias Hanrieder, Laura Jung, Horst Ruppach, Albert Mihranyan
Publikováno v:
Membranes, Vol 9, Iss 1, p 1 (2018)
Pore-size distribution (PSD) is the most critical parameter for size-exclusion virus removal filters. Yet, different dry- and wet-state porometry methods yield different pore-size values. The goal of this work is to conduct comparative analysis of ni
Externí odkaz:
https://doaj.org/article/37edd7358a0846459f6be3daee35e5ec
Publikováno v:
Cell and Gene Therapy Insights. 7:1411-1421
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf5ad898ebea4b59a4a3de5b745e1fea
https://doi.org/10.18609/cgti.2021.185
https://doi.org/10.18609/cgti.2021.185
Autor:
Paul W. Barone, Flora J. Keumurian, Caleb Neufeld, Andrea Koenigsberg, Robert Kiss, James Leung, Michael Wiebe, Rima Ait-Belkacem, Chakameh Azimpour Tabrizi, Cristina Barbirato, Pascale Beurdeley, Audrey Brussel, Jean-Pol Cassart, Colette Cote, Noémie Deneyer, Veera Dheenadhayalan, Leyla Diaz, Angela Geiselhoeringer, Maria M. Gilleece, Jakob Goldmann, Danielle Hickman, Angela Holden, Björn Keiner, Martina Kopp, Thomas R. Kreil, Christophe Lambert, Carine Logvinoff, Brandye Michaels, Jens Modrof, Brian Mullan, Jürgen Mullberg, Marie Murphy, Sean O'Donnell, José Peña, Michael Ruffing, Horst Ruppach, Nasrin Salehi, Shahjahan Shaid, Lindsey Silva, Richard Snyder, Mélancolie Spedito-Jovial, Olivier Vandeputte, Bernice Westrek, Bin Yang, Ping Yang, Stacy L. Springs
Publikováno v:
Biologicals : journal of the International Association of Biological Standardization.
The Consortium on Adventitious Agent Contamination in Biomanufacturing (CAACB) collected historical data from 20 biopharmaceutical industry members on their experience with the in vivo adventitious virus test, the in vitro virus test, and the use of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18fdade44cfe97b4941436ee939b7239
https://pubmed.ncbi.nlm.nih.gov/36621353
https://pubmed.ncbi.nlm.nih.gov/36621353
Autor:
Horst Ruppach
Publikováno v:
Drug discovery today. Technologies. 37
This review summarizes the viral safety concepts applied for cell line derived recombinants including biosimilars. The major aspects – material sourcing, testing, and viral clearance – are outlined and essentials per aspect to be considered descr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::786cb7849bf643fb06fc5e4d2e80f2ba
https://pubmed.ncbi.nlm.nih.gov/34895652
https://pubmed.ncbi.nlm.nih.gov/34895652
Autor:
Laura David, Horst Ruppach, Martin Lobedann, Peter Schwan, Gerhard Schembecker, Michael Lasse, Benjamin Maiser
Publikováno v:
Biotechnology and Bioengineering. 116:857-869
Continuous processing for the production of monoclonal antibodies (mAb) gains more and more importance. Several solutions exist for all the necessary production steps, leading to the possibility to build fully continuous processes. Low pH viral inact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0658912cc56bd950afcf90abdea385bf
https://doi.org/10.1002/bit.26872
https://doi.org/10.1002/bit.26872
Autor:
Rudolf Zirwes, Benoit Flan, Horst Ruppach, Marc Eloit, Alice Marinaci, Charles Hebert, Jean-Marie Charpin, Erika Muth, Justine Cheval, Audrey Brussel, Pascale Beurdeley, Kerstin Brack
Publikováno v:
Biologicals
Biologicals, Elsevier, 2019, 59, pp.29-36. ⟨10.1016/j.biologicals.2019.03.008⟩
Biologicals, Elsevier, 2019, 59, pp.29-36. ⟨10.1016/j.biologicals.2019.03.008⟩
The utilization of the current combination of in vitro, in vivo and PCR assays for the identification of adventitious viruses in production cells has a limited range of detection. While Next Generation Sequencing (NGS) has a broader breadth of detect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1316d3141ff1b27082d41949ede98bee
https://hal.archives-ouvertes.fr/hal-03477750/file/S1045105619300260.pdf
https://hal.archives-ouvertes.fr/hal-03477750/file/S1045105619300260.pdf
Autor:
Horst Ruppach
Publikováno v:
BioProcessing Journal. 12:24-30
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4974930cc00b15fbc46964d7f1b189a
https://doi.org/10.12665/j124.ruppach
https://doi.org/10.12665/j124.ruppach
Autor:
Philippe de Vilmorin, Horst Ruppach, Paul Genest, Tareq Jaber, Ashley Slocum, Oliver Schaefer
Publikováno v:
PDA journal of pharmaceutical science and technology. 69(3)
This article describes a four virus panel validation of EMD Millipore9s (Bedford, MA) small virus–retentive filter, Viresolve® Pro, using TrueSpikeTM viruses for a Biogen Idec process intermediate. The study was performed at Charles River Labs in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c15813a88e3bb246df1b63d39c79e6b4
https://pubmed.ncbi.nlm.nih.gov/26048749
https://pubmed.ncbi.nlm.nih.gov/26048749