Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Horst Olschewsk"'
Publikováno v:
SAGE Open Medical Case Reports, Vol 12 (2024)
Pulmonary veno-occlusive disease has a significantly worse prognosis than idiopathic pulmonary arterial hypertension. According to a case series from France, the median survival time from diagnosis to death or lung transplantation was only 1 year, an
Externí odkaz:
https://doaj.org/article/a8451b9192d442fe86a19ac4502d6816
Autor:
Katarina Zeder, Teresa Sassmann, Vasile Foris, Philipp Douschan, Horst Olschewski, Gabor Kovacs
Publikováno v:
International Journal of Cardiology Congenital Heart Disease, Vol 17, Iss , Pp 100519- (2024)
Rationale: Severe pulmonary hypertension (PH) in chronic obstructive pulmonary disease (COPD) is currently defined by an elevated mean pulmonary arterial pressure and strongly elevated pulmonary vascular resistance >5 wood units. Clinically, these pa
Externí odkaz:
https://doaj.org/article/86d84c02f6d14a54bbe3bbfdaac2b777
Autor:
Teresa Sassmann, Philipp Douschan, Vasile Foris, Natascha Tröster, Katarina Zeder, Luka Brcic, Adrienn Tornyos, Gerhard Bachmaier, Michael Fuchsjäger, Horst Olschewski, Gabor Kovacs
Publikováno v:
Respiratory Research, Vol 23, Iss 1, Pp 1-10 (2022)
Abstract Background Pulmonary hypertension (PH) is a frequent complication in COPD and it is associated with decreased exercise capacity and poor prognosis. We hypothesized that even in COPD patients without significant PH at rest, abnormal pulmonary
Externí odkaz:
https://doaj.org/article/714192d0a4f34031b2fd0d93de53f2cc
Autor:
Katharina Jandl, Johannes Lorenz Berg, Anna Birnhuber, Elisabeth Fliesser, Izabela Borek, Benjamin Seeliger, Sascha David, Julius J. Schmidt, Gregor Gorkiewicz, Martin Zacharias, Tobias Welte, Horst Olschewski, Akos Heinemann, Malgorzata Wygrecka, Grazyna Kwapiszewska
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundImmune cell recruitment, endothelial cell barrier disruption, and platelet activation are hallmarks of lung injuries caused by COVID-19 or other insults which can result in acute respiratory distress syndrome (ARDS). Basement membrane (BM)
Externí odkaz:
https://doaj.org/article/34c7951c8291486580ab2715b0a130c2
Autor:
Vasile Foris, Gabor Kovacs, Alexander Avian, Zoltán Bálint, Philipp Douschan, Bahil Ghanim, Walter Klepetko, Andrea Olschewski, Horst Olschewski
Publikováno v:
Frontiers in Physiology, Vol 13 (2023)
Background: NT-proBNP and GDF-15 are established blood-derived biomarkers for risk assessment in pulmonary hypertension (PH), despite limited sensitivity and specificity. Apelin has a crucial function in endothelial homeostasis, thus it might represe
Externí odkaz:
https://doaj.org/article/9b4ebb590a874cb0a61e6b956be28d58
Publikováno v:
Breathe, Vol 18, Iss 4 (2022)
In the recently published European Society of Cardiology/European Respiratory Society guidelines on the diagnosis and treatment of pulmonary hypertension (PH) the haemodynamic definitions of PH were updated and a new definition for exercise PH was in
Externí odkaz:
https://doaj.org/article/c0f431c4e0e94aea93248c98fe5b7821
Autor:
Slaven Crnkovic, Francesco Valzano, Elisabeth Fließer, Jürgen Gindlhuber, Helene Thekkekara Puthenparampil, Maria Basil, Mike P. Morley, Jeremy Katzen, Elisabeth Gschwandtner, Walter Klepetko, Edward Cantu, Heimo Wolinski, Horst Olschewski, Jörg Lindenmann, You-Yang Zhao, Edward E. Morrisey, Leigh M. Marsh, Grazyna Kwapiszewska
Publikováno v:
JCI Insight, Vol 7, Iss 20 (2022)
A central feature of progressive vascular remodeling is altered smooth muscle cell (SMC) homeostasis; however, the understanding of how different cell populations contribute to this process is limited. Here, we utilized single-cell RNA sequencing to
Externí odkaz:
https://doaj.org/article/44b0a9ebfeff415b9c53d340fe872d68
Autor:
Elisabeth Fließer, Anna Birnhuber, Leigh M Marsh, Elisabeth Gschwandtner, Walter Klepetko, Horst Olschewski, Grazyna Kwapiszewska
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 7, Iss 5, Pp 446-458 (2021)
Abstract Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) poses a serious threat to healthcare systems worldwide. Binding of the virus to angiotensin‐converting enzyme 2 (ACE2) is an important step in the infection mechanism. Howeve
Externí odkaz:
https://doaj.org/article/f5f16b2ed5bc414591ae7c885504834b
Autor:
Gert Reiter, Gabor Kovacs, Clemens Reiter, Albrecht Schmidt, Michael Fuchsjäger, Horst Olschewski, Ursula Reiter
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundMean pulmonary artery wedge pressure (PAWP) represents a right heart catheter (RHC) surrogate measure for mean left atrial (LA) pressure and is crucial for the clinical classification of pulmonary hypertension (PH). Hypothesizing that PAWP
Externí odkaz:
https://doaj.org/article/cee2d62f3a70422dadffa9ac9ee17e1e
Autor:
Sylvia M. Nikkho, Manuel J. Richter, Eric Shen, Steven H. Abman, Katerina Antoniou, Jonathan Chung, Peter Fernandes, Paul Hassoun, Howard M. Lazarus, Horst Olschewski, Lucilla Piccari, Mitchell Psotka, Rajan Saggar, Oksana A. Shlobin, Norman Stockbridge, Patrizio Vitulo, Carmine Dario Vizza, Stephen J. Wort, Steven D. Nathan
Publikováno v:
Pulmonary Circulation, Vol 12, Iss 3, Pp n/a-n/a (2022)
Abstract Pulmonary hypertension (PH) has been linked to worse outcomes in chronic lung diseases. The presence of PH in the setting of underlying Interstitial Lung Disease (ILD) is strongly associated with decreased exercise and functional capacity, a
Externí odkaz:
https://doaj.org/article/218979fd55614332832c91abea59ce7c