Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Horst Ahorn"'
Autor:
Carol Murphy, Elissavet Hatzi, Horst Ahorn, Lothar Schweigerer, Ulrike Tontsch, Keiko Yamauchi-Takihara, Ana-Maria Bamberger, Theodore Fotsis, Andreas Zoephel
Publikováno v:
European Journal of Biochemistry. 269:3732-3741
Amplification of N-myc oncogene is a frequent event in advanced stages of human neuroblastoma and correlates with poor prognosis and enhanced neovascularization. Angiogenesis is an indispensable prerequisite for the progression and metastasis of soli
Autor:
Gerda Weber, Horst Ahorn, Wolfgang J. Rettig, Maria Novatchkova, John Edward Park, Pilar Garin-Chesa, Sven Christian, Martin Lenter, Frank Eisenhaber
Publikováno v:
Journal of Biological Chemistry. 276:48588-48595
EndoGlyx-1, the antigen identified with the monoclonal antibody H572, is a pan-endothelial human cell surface glycoprotein complex composed of four different disulfide-bonded protein species with an apparent molecular mass of approximately 500 kDa. H
Autor:
Horst Ahorn, Rudolf Hauptmann, Herbert Nar, Walter Spevak, Alexander Pautsch, Andreas Zoephel
Publikováno v:
Structure. 9:955-965
Background: The insulin-like growth-factor-1 (IGF-1) receptor, which is widely expressed in cells that have undergone oncogenic transformation, is emerging as a novel target in cancer therapy. IGF-1-induced receptor activation results in autophosphor
Autor:
Horst Ahorn, Martin Lenter, John Edward Park, Hans-Peter Rodi, Andreas Koehler, Frank Eisenhaber, Wolfgang J. Rettig, Pilar Garin-Chesa, Sven Christian
Publikováno v:
Journal of Biological Chemistry. 276:7408-7414
Endosialin, the antigen identified with monoclonal antibody FB5, is a highly restricted 165-kDa cell surface glycoprotein expressed by tumor blood vessel endothelium in a broad range of human cancers but not detected in blood vessels or other cell ty
Publikováno v:
International Journal of Cancer. 91:180-186
The development of human cancer is caused by complex molecular perturbations leading to variable clinical behavior often even in single disease entities. To prove that expression profiling on the protein level can be correlated with clinical data we
Autor:
Elisa Bofill-Cardona, Christian Nanoff, Horst Ahorn, Qiong Yang, Oliver Kudlacek, Michael Freissmuth
Publikováno v:
Journal of Biological Chemistry. 275:32672-32680
Signaling by D(2)-dopamine receptors in neurons likely proceeds in the presence of Ca(2+) oscillations. We describe here the biochemical basis for a cross-talk between intracellular Ca(2+) and the D(2) receptor. By activation of calmodulin (CaM), Ca(
Publikováno v:
Biochemical Journal. 342:33-39
Upon expression and purification of the first catalytic domain of mammalian adenylate cyclase type 1 (IC1), a 27 kDa contaminant was observed, which was labelled by three radioactive ATP analogues (8-azido-ATP, 3′-O-(4-benzoyl)benzoyl-ATP and 2′,
Autor:
Christof Ebner, Horst Ahorn, Gabriel O'Riordain, Karin Hoffmann-Sommergruber, Heimo Breiteneder, Claudia Inschlag, Otto Scheiner
Publikováno v:
International Archives of Allergy and Immunology. 116:22-28
Background: The prevalence of allergy to fruits and vegetables increased with pollinosis over the last 10 years. So far, clusters of hypersensitivity have been established and corroborated by the molecular characterization of individual cross-reactin
Publikováno v:
Electrophoresis. 18:2582-2590
Protein targeting and sorting is accomplished by complex vesicular transport processes that are tightly regulated within a cell. This is especially important for epithelial cells because correct delivery of newly synthesized proteins as well as recyc
Autor:
Susanne Susani, Elinborg Ostermann, Paul Beaumier, Horst Ahorn, Erik Patzelt, Günther R. Adolf, Karl Heinz Heider, Sproll Marlies
Publikováno v:
Cancer Immunology, Immunotherapy. 43:245-253
Variant isoforms of CD44, a family of cell-surface glycoproteins generated by alternative splicing and post-translational modifications, are expressed in a variety of human tumors and play important roles in tumor progression and metastasis formation