Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Horst Honeck"'
Autor:
Friedrich C. Luft, Horst Honeck, Wolf-Hagen Schunck, Kirill Essin, Peter Ruth, Maik Gollasch, John R. Falck, Hantz C. Hercule, Birgit Salanova, Matthias Sausbier
Publikováno v:
Experimental Physiology. 92:1067-1076
17,18-Epoxyeicosatetraenoic acid (17,18-EETeTr) stimulates vascular large-conductance K(+) (BK) channels. BK channels are composed of the pore-forming BK alpha and auxiliary BK beta1 subunits that confer an increased sensitivity for changes in membra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18df7c5847b928c6739910fc4b30138e
https://doi.org/10.1113/expphysiol.2007.038166
https://doi.org/10.1113/expphysiol.2007.038166
Autor:
Wolf-Hagen Schunck, Horst Honeck, Marija Markovic, Eduardo Barbosa-Sicard, Baghat Christ, Dominik N. Müller
Publikováno v:
Biochemical and Biophysical Research Communications. 329:1275-1281
CYP2C enzymes epoxidize arachidonic acid (AA) to metabolites involved in the regulation of vascular and renal function. We tested the hypothesis that eicosapentaenoic acid (EPA), a n-3 polyunsaturated fatty acid, may serve as an alternative substrate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74df615c5cc43080a81304162651761a
https://doi.org/10.1016/j.bbrc.2005.02.103
https://doi.org/10.1016/j.bbrc.2005.02.103
Autor:
Spencer S. Ericksen, Horst Honeck, Dieter Schwarz, Pyotr Kisselev, Wolf-Hagen Schunck, Grazyna D. Szklarz, Alexey Chernogolov, Ivar Roots
Publikováno v:
Biochemical Pharmacology. 67:1445-1457
Human cytochrome P450 1A1 (CYP1A1) and human NADPH-cytochrome P450 reductase were expressed and purified from Spodoptera frugiperda insect cells. A reconstituted enzymatically active system metabolized polyunsaturated fatty acids such as arachidonic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc66a55428e5d58aea4624e9b95d2f47
https://doi.org/10.1016/j.bcp.2003.12.023
https://doi.org/10.1016/j.bcp.2003.12.023
Autor:
Vladimir M. Shkumatov, Y. S. Poljakov, Horst Honeck, Wolf-Hagen Schunck, Stephan Mauersberger, A. A. Chernogolov, V. G. Radyuk, N. S. Frolova, E. V. Usova
Publikováno v:
Biochemistry (Moscow). 67:456-467
The cDNA encoding cytochrome P-45017alpha from bovine adrenal cortex was expressed in Saccharomyces cerevisiae under the control of the galactose-inducible GAL10 promoter. Carbon monoxide difference spectra of the galactose-induced yeast cells showed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d489d170d25d4eeee110fe6c9b117cd3
https://doi.org/10.1023/a:1015290108071
https://doi.org/10.1023/a:1015290108071
Autor:
Ralf Dr. Neunaber, Anna Franca Milia, Wolfgang Schneider, Friedrich C. Luft, Eva Kärgel, Bettina Erdmann, Volkmar Gross, Wolf-Hagen Schunck, Horst Honeck
Publikováno v:
Scopus-Elsevier
Abstract —Cytochrome P450 (P450)-dependent arachidonic acid metabolites may act as mediators in the regulation of vascular tone and renal function. We studied arachidonic acid hydroxylase activities in renal microsomes from normotensive NMRI mice,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a971657439e25f95ca4574e1f3c5c380
https://doi.org/10.1161/01.hyp.36.4.610
https://doi.org/10.1161/01.hyp.36.4.610
Publikováno v:
Yeast. 12:333-348
A full-length cDNA for NADPH-cytochrome P450 reductase from Candida maltosa was cloned and sequenced. The derived amino acid sequence showed a high similarity to the reductases from other eukaryotes. Expression in Saccharomyces cerevisiae under contr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::847fcad1f59520afe8d438dac134de20
https://doi.org/10.1002/(sici)1097-0061(19960330)12:4<333::aid-yea915>3.0.co
https://doi.org/10.1002/(sici)1097-0061(19960330)12:4<333::aid-yea915>3.0.co
Autor:
Hantz C, Hercule, Birgit, Salanova, Kirill, Essin, Horst, Honeck, John R, Falck, Matthias, Sausbier, Peter, Ruth, Wolf-Hagen, Schunck, Friedrich C, Luft, Maik, Gollasch
Publikováno v:
Experimental physiology. 92(6)
17,18-Epoxyeicosatetraenoic acid (17,18-EETeTr) stimulates vascular large-conductance K(+) (BK) channels. BK channels are composed of the pore-forming BK alpha and auxiliary BK beta1 subunits that confer an increased sensitivity for changes in membra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2ac9c59030817fed79ef08d00b8f2b42
https://pubmed.ncbi.nlm.nih.gov/17675416
https://pubmed.ncbi.nlm.nih.gov/17675416
Autor:
Eduardo Barbosa-Sicard, Maren Wellner, Cosima Schmidt, Dominik N. Müller, Wolf-Hagen Schunck, Horst Honeck, Volkmar Gross, Friedrich C. Luft, Marija Markovic, Hantz C. Hercule
Publikováno v:
The Biochemical journal. 403(1)
AA (arachidonic acid) hydroxylation to 20-HETE (20-hydroxyeicosatetraenoic acid) influences renal vascular and tubular function. To identify the CYP (cytochrome P450) isoforms catalysing this reaction in the mouse kidney, we analysed the substrate sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc6385e8977c0756602d49e9a8640e7a
https://pubmed.ncbi.nlm.nih.gov/17112342
https://pubmed.ncbi.nlm.nih.gov/17112342
Autor:
Hermann Haller, Anette Fiebeler, Dominik N. Müller, Marija Markovic, Joon-Keun Park, Michael Rothe, Horst Honeck, Maren Wellner, Eva Kaergel, Torsten Kirsch, Juergen Theuer, Erdenechimeg Shagdarsuren, Wolf-Hagen Schunck, Friedrich C. Luft, Ralf Dechend, Eduardo Barbosa-Sicard
Publikováno v:
The American journal of pathology. 164(2)
Cytochrome P450 (CYP)-dependent arachidonic acid (AA) metabolites are involved in the regulation of renal vascular tone and salt excretion. The epoxygenation product 11,12-epoxyeicosatrienoic acid (EET) is anti-inflammatory and inhibits nuclear facto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d763ca4bdf60bbf8b4930252d0e17f9e
https://pubmed.ncbi.nlm.nih.gov/14742258
https://pubmed.ncbi.nlm.nih.gov/14742258
Autor:
Horst Honeck, Wolf-Hagen Schunck, Eva Kaergel, Juergen Theuer, Alexander Mullally, Dominik N. Müller, Friedrich C. Luft, Erdenechimeg Shagdarsuren
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 40(3)
Transgenic rats overexpressing both human renin and angiotensinogen genes (dTGR) develop hypertension, inflammation, and renal failure. We tested the hypothesis that these pathological features are associated with changes in renal P450-dependent arac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::208867ac16487b13db358b2b84114269
https://pubmed.ncbi.nlm.nih.gov/12215466
https://pubmed.ncbi.nlm.nih.gov/12215466