Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Horng-Shen Chen"'
Autor:
Alessandra De Leo, Zhong Deng, Olga Vladimirova, Horng-Shen Chen, Jayaraju Dheekollu, Abram Calderon, Kenneth A Myers, James Hayden, Frederick Keeney, Benedikt B Kaufer, Yan Yuan, Erle Robertson, Paul M Lieberman
Publikováno v:
PLoS Pathogens, Vol 15, Iss 1, p e1007489 (2019)
The molecular basis for the formation of functional, higher-ordered macro-molecular domains is not completely known. The Kaposi's Sarcoma-Associated Herpesvirus (KSHV) genome forms a super-molecular domain structure during latent infection that is st
Externí odkaz:
https://doaj.org/article/a812466a180a406f95aa2bba0e3334fc
Publikováno v:
PLoS Pathogens, Vol 14, Iss 4, p e1007027 (2018)
[This corrects the article DOI: 10.1371/journal.ppat.1006596.].
Externí odkaz:
https://doaj.org/article/3275904de43e47b8b6a049c291b73cce
Publikováno v:
PLoS Pathogens, Vol 13, Iss 8, p e1006596 (2017)
Kaposi's sarcoma (KS)-associated herpesvirus (KSHV) is a human gammaherpesvirus recognized as the principal causative agent of KS and primary effusion lymphoma (PEL). KSHV establishes persistent latent infection in B lymphocytes where viral gene expr
Externí odkaz:
https://doaj.org/article/89a2832e27ee48eb9ddecb0a0f03324a
Autor:
Horng-Shen Chen, Alessandra De Leo, Zhuo Wang, Andrew Kerekovic, Robert Hills, Paul M Lieberman
Publikováno v:
PLoS Pathogens, Vol 13, Iss 1, p e1006100 (2017)
Kaposi's Sarcoma-associated Herpesvirus (KSHV) establishes stable latent infection in B-lymphocytes and pleural effusion lymphomas (PELs). During latency, the viral genome persists as an epigenetically constrained episome with restricted gene express
Externí odkaz:
https://doaj.org/article/8535c5627a174e3d81acc086c7e5b4ee
Autor:
Fang Lu, Horng-Shen Chen, Andrew V Kossenkov, Karen DeWispeleare, Kyoung-Jae Won, Paul M Lieberman
Publikováno v:
PLoS Pathogens, Vol 12, Iss 1, p e1005339 (2016)
Epstein-Barr Virus (EBV) transforms resting B-lymphocytes into proliferating lymphoblasts to establish latent infections that can give rise to malignancies. We show here that EBV-encoded transcriptional regulator EBNA2 drives the cooperative and comb
Externí odkaz:
https://doaj.org/article/92d36962e2914636ad6de0021e328fd4
Publikováno v:
PLoS Pathogens, Vol 9, Iss 10, p e1003672 (2013)
LANA is the KSHV-encoded terminal repeat binding protein essential for viral replication and episome maintenance during latency. We have determined the X-ray crystal structure of LANA C-terminal DNA binding domain (LANADBD) to reveal its capacity to
Externí odkaz:
https://doaj.org/article/9c6a1fdbd15c4d32b17a26c6bb03e431
Autor:
Horng-Shen Chen, 陳宏申
107
The whole process of new drug development includes the exploration and efficacy study of early drug candidates, as well as preclinical animal tests and clinical human trials for product development. After confirming the clinical efficacy and
The whole process of new drug development includes the exploration and efficacy study of early drug candidates, as well as preclinical animal tests and clinical human trials for product development. After confirming the clinical efficacy and
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/gj5g92
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 14, Iss 4, p e1007027 (2018)
PLoS Pathogens, Vol 14, Iss 4, p e1007027 (2018)
Kaposi’s sarcoma (KS)-associated herpesvirus (KSHV) is a human gammaherpesvirus recognized as the principal causative agent of KS and primary effusion lymphoma (PEL). KSHV establishes persistent latent infection in B lymphocytes where viral gene ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dec8338c6fa3169fe8fdbe9f4603a9ad
https://pubmed.ncbi.nlm.nih.gov/28854249
https://pubmed.ncbi.nlm.nih.gov/28854249
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 13, Iss 8, p e1006596 (2017)
PLoS Pathogens, Vol 13, Iss 8, p e1006596 (2017)
Kaposi's sarcoma (KS)-associated herpesvirus (KSHV) is a human gammaherpesvirus recognized as the principal causative agent of KS and primary effusion lymphoma (PEL). KSHV establishes persistent latent infection in B lymphocytes where viral gene expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7f28093ec98248f00115c7ff48a9dce
https://pubmed.ncbi.nlm.nih.gov/29694443
https://pubmed.ncbi.nlm.nih.gov/29694443
Autor:
Joshua M. Mueller, Kayla A. Martin, Italo Tempera, Lena N. Lupey, Horng-Shen Chen, Paul M. Lieberman, Fang Lu
Publikováno v:
Journal of Virology. 88:1703-1713
The chromatin regulatory factors CTCF and cohesin have been implicated in the coordinated control of multiple gene loci in Epstein-Barr virus (EBV) latency. We have found that CTCF and cohesin are highly enriched at the convergent and partially overl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::081b77ba96526ad43088d56176d9af8b
https://doi.org/10.1128/jvi.02209-13
https://doi.org/10.1128/jvi.02209-13