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Akademický článek

Sodium Iodate Disrupted the Mitochondrial-Lysosomal Axis in Cultured Retinal Pigment Epithelial Cells.

Autor: Lin YC; 1 Institute of Biopharmaceutical Sciences, School of Pharmaceutical Sciences, National Yang-Ming University , Taipei, Taiwan .; 2 Department of Ophthalmology, Yang-Ming branch, Taipei City Hospital , Taipei, Taiwan ., Horng LY; 1 Institute of Biopharmaceutical Sciences, School of Pharmaceutical Sciences, National Yang-Ming University , Taipei, Taiwan .; 3 Research Center for Drug Discovery, National Yang-Ming University , Taipei, Taiwan ., Sung HC; 3 Research Center for Drug Discovery, National Yang-Ming University , Taipei, Taiwan ., Wu RT; 1 Institute of Biopharmaceutical Sciences, School of Pharmaceutical Sciences, National Yang-Ming University , Taipei, Taiwan .; 3 Research Center for Drug Discovery, National Yang-Ming University , Taipei, Taiwan .; 4 Graduate Institute of Natural Products, College of Pharmacy, Kaohsiung Medical University , Kaohsiung, Taiwan .

Publikováno v: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics [J Ocul Pharmacol Ther] 2018 Sep; Vol. 34 (7), pp. 500-511. Date of Electronic Publication: 2018 Jul 18.

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Akademický článek

Total Synthesis of (+)-Medicarpin.

Autor: Yang X; Natural Products Research Laboratories, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina 27599, United States., Zhao Y; Natural Products Research Laboratories, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina 27599, United States., Hsieh MT; Natural Products Research Laboratories, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina 27599, United States.; Chinese Medicine Research and Development Center, China Medical University and Hospital , Taichung 40402, Taiwan.; School of Pharmacy, China Medical University , Taichung 404, Taiwan., Xin G; Natural Products Research Laboratories, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina 27599, United States., Wu RT; Research Center for Drug Discovery, National Yang-Ming University , Taipei 112, Taiwan., Hsu PL; Research Center for Drug Discovery, National Yang-Ming University , Taipei 112, Taiwan., Horng LY; Research Center for Drug Discovery, National Yang-Ming University , Taipei 112, Taiwan., Sung HC; Research Center for Drug Discovery, National Yang-Ming University , Taipei 112, Taiwan., Cheng CH; PhytoHealth Corporation, Maywafa Biopharma Group, Taipei 105, Taiwan., Lee KH; Natural Products Research Laboratories, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina 27599, United States.; Chinese Medicine Research and Development Center, China Medical University and Hospital , Taichung 40402, Taiwan.

Publikováno v: Journal of natural products [J Nat Prod] 2017 Dec 22; Vol. 80 (12), pp. 3284-3288. Date of Electronic Publication: 2017 Nov 22.

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Akademický článek

Activating mitochondrial function and haemoglobin expression with EH-201, an inducer of erythropoietin in neuronal cells, reverses memory impairment.

Autor: Horng LY; Institute of Biopharmaceutical Sciences, National Yang-Ming University, Taipei, Taiwan.; Research Center for Drug Discovery, National Yang-Ming University, Taipei, Taiwan., Hsu PL; Research Center for Drug Discovery, National Yang-Ming University, Taipei, Taiwan., Chen LW; Institute of Biopharmaceutical Sciences, National Yang-Ming University, Taipei, Taiwan., Tseng WZ; Institute of Biopharmaceutical Sciences, National Yang-Ming University, Taipei, Taiwan., Hsu KT; Institute of Biopharmaceutical Sciences, National Yang-Ming University, Taipei, Taiwan., Wu CL; Research Center for Drug Discovery, National Yang-Ming University, Taipei, Taiwan., Wu RT; Institute of Biopharmaceutical Sciences, National Yang-Ming University, Taipei, Taiwan.; Research Center for Drug Discovery, National Yang-Ming University, Taipei, Taiwan.; Research Center for Natural Products and Drug Development, Institute of Natural Products, Kaohsiung Medical University, Kaohsiung, Taiwan.

Publikováno v: British journal of pharmacology [Br J Pharmacol] 2015 Oct; Vol. 172 (19), pp. 4741-56. Date of Electronic Publication: 2015 Aug 10.

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Akademický článek

Internal ribosome entry site of bFGF is the target of thalidomide for IMiDs development in multiple myeloma.

Autor: Lien IC; Institute of Biopharmaceutical Sciences, National Yang-Ming University, Taipei, ROC (Taiwan)., Horng LY; Institute of Biopharmaceutical Sciences, National Yang-Ming University, Taipei, ROC (Taiwan) ; Research Centre for Drug Discovery, National Yang-Ming University, Taipei, ROC (Taiwan)., Hsu PL; Research Centre for Drug Discovery, National Yang-Ming University, Taipei, ROC (Taiwan)., Wu CL; Research Centre for Drug Discovery, National Yang-Ming University, Taipei, ROC (Taiwan)., Sung HC; Research Centre for Drug Discovery, National Yang-Ming University, Taipei, ROC (Taiwan)., Wu RT; Institute of Biopharmaceutical Sciences, National Yang-Ming University, Taipei, ROC (Taiwan) ; Research Centre for Drug Discovery, National Yang-Ming University, Taipei, ROC (Taiwan).

Publikováno v: Genes & cancer [Genes Cancer] 2014 Mar; Vol. 5 (3-4), pp. 127-41.

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Akademický článek

Activation of mitochondrial function and Hb expression in non-haematopoietic cells by an EPO inducer ameliorates ischaemic diseases in mice.

Autor: Hsu PL; Institute of Biopharmaceutical Sciences, National Yang-Ming University, Taipei, Taiwan., Horng LY, Peng KY, Wu CL, Sung HC, Wu RT

Publikováno v: British journal of pharmacology [Br J Pharmacol] 2013 Aug; Vol. 169 (7), pp. 1461-76.

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Activating mitochondrial regulator PGC-1α expression by astrocytic NGF is a therapeutic strategy for Huntington's disease.

Autor: Chen LW; Institute of Biopharmaceutical Sciences, National Yang-Ming University, Shih-Pai, Taipei, Taiwan, ROC. penny8989@yahoo.com.tw, Horng LY, Wu CL, Sung HC, Wu RT

Publikováno v: Neuropharmacology [Neuropharmacology] 2012 Sep; Vol. 63 (4), pp. 719-32. Date of Electronic Publication: 2012 May 24.

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Akademický článek

Hepatocyte growth factor has a role in the amelioration of diabetic vascular complications via autophagic clearance of advanced glycation end products: Dispo85E, an HGF inducer, as a potential botanical drug.

Autor: Peng KY; Institute of Biopharmaceutical Science, School of Pharmaceutical Science, National Yang-Ming University, Taipei City 112, Taiwan, Republic of China., Horng LY, Sung HC, Huang HC, Wu RT

Publikováno v: Metabolism: clinical and experimental [Metabolism] 2011 Jun; Vol. 60 (6), pp. 888-92. Date of Electronic Publication: 2010 Oct 30.

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