Zobrazeno 1 - 10
of 282
pro vyhledávání: '"Horng H. Chen"'
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 15 (2022)
Background A high prevalence of preclinical heart failure (HF) (Stages A and B) has previously been shown. The aim of this study was to explore factors associated with the incidence of preclinical HF in a community population. Methods and Results Ret
Externí odkaz:
https://doaj.org/article/71caefb570434b1d90717456e73893c9
Autor:
Marat Fudim, Nicolas Ashur, Aaron D. Jones, Andrew P. Ambrosy, Bradley A. Bart, Javed Butler, Horng H. Chen, Stephen J. Greene, Yogesh Reddy, Margaret M. Redfield, Abhinav Sharma, Adrian F. Hernandez, Gary Michael Felker, Barry A. Borlaug, Robert J. Mentz
Publikováno v:
ESC Heart Failure, Vol 8, Iss 1, Pp 662-669 (2021)
Abstract Aims Heart failure with preserved ejection fraction (HFpEF) is a heterogeneous condition, and tissue congestion manifested by oedema is not present in all patients. We compared clinical characteristics, exercise capacity, and outcomes in pat
Externí odkaz:
https://doaj.org/article/9d162872eedd410d8fbb305b0a3ae4b5
Autor:
Fadi W. Adel, Ye Zheng, Siu-Hin Wan, Christie Greason, Shuchong Pan, Syed Ameenuddin, Horng H. Chen
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
The incidence of diabetes mellitus (DM) is rising. DM is a risk factor for developing left ventricular (LV) dysfunction and adverse cardiovascular outcomes. Insulin, commonly used to treat DM, is associated with further worsening of such outcomes. Ye
Externí odkaz:
https://doaj.org/article/3d8a6afca12347048bc37c7697bae807
Autor:
Scott A. Hubers, Siu‐Hin Wan, Fadi W. Adel, Sherry L. Benike, John C. Burnett, Christopher Scott, Horng H. Chen
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 2 (2022)
Background Phosphodiesterase V (PDEV) is upregulated in heart failure, leading to increased degradation of cGMP and impaired natriuresis. PDEV inhibition improves the renal response to B‐type natriuretic peptide in animal models. We tested the hypo
Externí odkaz:
https://doaj.org/article/4ff4a56f6ebf43bebf386f316d8a32d9
Autor:
Siu-Hin Wan, MD, Isabel Torres-Courchoud, MD, PhD, Paul M. McKie, MD, Joshua P. Slusser, BSc, Margaret M. Redfield, MD, John C. Burnett, Jr., MD, David O. Hodge, MS, Horng H. Chen, MBBCh
Publikováno v:
JACC: Basic to Translational Science, Vol 4, Iss 8, Pp 962-972 (2019)
Summary: Impaired cardiorenal response to acute saline volume expansion in preclinical systolic dysfunction (PSD) may lead to symptomatic heart failure. The objective was to determine if combination phosphodiesterase-V inhibition and exogenous B-type
Externí odkaz:
https://doaj.org/article/153cd326353a455db84767e46f53293b
Autor:
Siu‐Hin Wan, Paul M. McKie, Joshua P. Slusser, John C. Burnett Jr, David O. Hodge, Horng H. Chen
Publikováno v:
Physiological Reports, Vol 9, Iss 16, Pp n/a-n/a (2021)
Abstract Preclinical diastolic dysfunction (PDD) results in impaired cardiorenal response to volume load (VL) which may contribute to the progression to clinical heart failure with preserved ejection fraction (HFpEF). The objective was to evaluate if
Externí odkaz:
https://doaj.org/article/6ee562d4be75489f9112badc5bb22eae
Publikováno v:
Mayo Clinic Proceedings: Innovations, Quality & Outcomes, Vol 2, Iss 2, Pp 148-154 (2018)
Objective: To determine the risks of acute kidney injury development and long-term clinical outcomes of patients with hypertensive crisis. Patients and Methods: This was a population study of Olmsted County residents with hypertensive crisis between
Externí odkaz:
https://doaj.org/article/eaee189054394246be5a21fcc6999a9c
Autor:
Omar F. AbouEzzeddine, Paul M. McKie, Shannon M. Dunlay, Susanna R. Stevens, G. Michael Felker, Barry A. Borlaug, Horng H. Chen, Russell P. Tracy, Eugene Braunwald, Margaret M. Redfield
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 2 (2017)
BackgroundSoluble ST2 is a biomarker that is elevated in certain systemic inflammatory diseases. Comorbidity‐driven microvascular inflammation is postulated to play a key role in heart failure with preserved ejection fraction (HFpEF) pathophysiolog
Externí odkaz:
https://doaj.org/article/ccc1caf301d441818319dbf233dfa034
Publikováno v:
Cardiovascular Research. 118:3416-3433
The discovery of the heart as an endocrine organ resulted in a remarkable recognition of the natriuretic peptide system (NPS). Specifically, research has established the production of atrial natriuretic peptide (ANP) and B-type natriuretic peptide (B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::676900200fb9a2f94b866dd9973f6183
https://doi.org/10.1093/cvr/cvac125
https://doi.org/10.1093/cvr/cvac125
Autor:
Xiao Ma, Seethalakshmi R. Iyer, Xiaoyu Ma, Shawn H. Reginauld, Yang Chen, Shuchong Pan, Ye Zheng, Dante G. Moroni, Yue Yu, Lianwen Zhang, Valentina Cannone, Horng H. Chen, Carlos M. Ferrario, S. Jeson Sangaralingham, John C. Burnett
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 10; Pages: 8547
The natriuretic peptide system (NPS) and renin-angiotensin-aldosterone system (RAAS) function oppositely at multiple levels. While it has long been suspected that angiotensin II (ANGII) may directly suppress NPS activity, no clear evidence to date su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b8b26044c60d6618a431e8ff230698d