Optical and pharmacological manipulation of hypoglossal motor nucleus identifies differential effects of taltirelin on sleeping tonic motor activity and responsiveness.

Autor: Aggarwal J; Department of Physiology, University of Toronto, 3206 Medical Sciences Building, 1 King's College Circle, Toronto, ON, M5S 1A8, Canada., Ladha R; Department of Physiology, University of Toronto, 3206 Medical Sciences Building, 1 King's College Circle, Toronto, ON, M5S 1A8, Canada., Liu WY; Department of Physiology, University of Toronto, 3206 Medical Sciences Building, 1 King's College Circle, Toronto, ON, M5S 1A8, Canada., Liu H; Department of Physiology, University of Toronto, 3206 Medical Sciences Building, 1 King's College Circle, Toronto, ON, M5S 1A8, Canada., Horner RL; Department of Physiology, University of Toronto, 3206 Medical Sciences Building, 1 King's College Circle, Toronto, ON, M5S 1A8, Canada. richard.horner@utoronto.ca.; Department of Medicine, University of Toronto, 3206 Medical Sciences Building, 1 King's College Circle, Toronto, ON, M5S 1A8, Canada. richard.horner@utoronto.ca.

Publikováno v: Scientific reports [Sci Rep] 2023 Jul 29; Vol. 13 (1), pp. 12299. Date of Electronic Publication: 2023 Jul 29.

Targets for obstructive sleep apnea pharmacotherapy: principles, approaches, and emerging strategies.

Autor: Horner RL; Departments of Physiology and Medicine, University of Toronto, Toronto, ON, Canada.

Publikováno v: Expert opinion on therapeutic targets [Expert Opin Ther Targets] 2023 Jul-Dec; Vol. 27 (7), pp. 609-626. Date of Electronic Publication: 2023 Jul 26.

Differential pharmacological and sex-specific effects of antimuscarinic agents at the hypoglossal motor nucleus in vivo in rats.

Autor: Niakani S; Department of Physiology, University of Toronto, Toronto, Canada., Liu H; Department of Physiology, University of Toronto, Toronto, Canada., Liu WY; Department of Physiology, University of Toronto, Toronto, Canada., Horner RL; Department of Physiology, University of Toronto, Toronto, Canada. richard.horner@utoronto.ca.; Department of Medicine, University of Toronto, 3206 Medical Sciences Building, 1 King's College Circle, Toronto, ON, M5S 1A8, Canada. richard.horner@utoronto.ca.

Publikováno v: Scientific reports [Sci Rep] 2022 Sep 01; Vol. 12 (1), pp. 14896. Date of Electronic Publication: 2022 Sep 01.

Optical Stimulation of Thalamic Spindle Circuitry Sustains Electroencephalogram Patterns of General Anesthesia but not Duration of Loss of Consciousness.

Autor: Mesbah-Oskui L; Department of Medicine, Queen's University, Kingston, Ontario K7L 3N6, Canada., Gurges P; Institute of Medical Science, University of Toronto, Toronto, Ontario M5S 1A8, Canada., Liu WY; Institute of Medical Science, University of Toronto, Toronto, Ontario M5S 1A8, Canada; State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Department of Pharmacology, School of Basic Medical Science, Fudan University, Shanghai 200032, China., Horner RL; Department of Physiology, University of Toronto, Toronto, Ontario M5S 1A8, Canada; Department of Medicine, University of Toronto, Toronto, Ontario M5S 1A8, Canada. Electronic address: richard.horner@utoronto.ca.

Publikováno v: Neuroscience [Neuroscience] 2021 Aug 01; Vol. 468, pp. 110-122. Date of Electronic Publication: 2021 Jun 12.

A Focal Inactivation and Computational Study of Ventrolateral Periaqueductal Gray and Deep Mesencephalic Reticular Nucleus Involvement in Sleep State Switching and Bistability.

Autor: Grace KP; Institute of Medical Science, University of Toronto, Toronto, Ontario M5S 1A8, Canada.; Department of Neurology, Beth Israel Deaconess Medical Center and Division of Sleep Medicine, Harvard Medical School, Boston, MA 02215., Horner RL; Department of Medicine, University of Toronto, Toronto, Ontario M5S 1A8, Canada kpgrace@bidmc.harvard.edu.; Department of Physiology, University of Toronto, Toronto, Ontario M5S 1A8, Canada.

Publikováno v: ENeuro [eNeuro] 2020 Oct 14; Vol. 7 (6). Date of Electronic Publication: 2020 Oct 14 (Print Publication: 2020).