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A brain-penetrant microtubule-targeting agent that disrupts hallmarks of glioma tumorigenesis.

Autor: Horne EA; Department of Pharmacology, University of Washington, Seattle, Washington, USA.; Stella Therapeutics, Inc., Pacific Northwest Research Institute, Seattle, Washington, USA., Diaz P; Department of Biomedical and Pharmaceutical Sciences, University of Montana, Missoula, Montana, USA.; DermaXon LLC, Missoula, Montana, USA., Cimino PJ; Department of Pathology, University of Washington, Seattle, Washington, USA., Jung E; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany., Xu C; Department of Pharmacology, University of Washington, Seattle, Washington, USA., Hamel E; Developmental Therapeutics Program, Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA., Wagenbach M; Department of Physiology and Biophysics, University of Washington, Seattle, Washington, USA., Kumasaka D; Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Wageling NB; DermaXon LLC, Missoula, Montana, USA., Azorín DD; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany., Winkler F; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany., Wordeman LG; Department of Physiology and Biophysics, University of Washington, Seattle, Washington, USA., Holland EC; Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Stella N; Department of Pharmacology, University of Washington, Seattle, Washington, USA.; Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, Washington, USA.

Publikováno v: Neuro-oncology advances [Neurooncol Adv] 2020 Dec 03; Vol. 3 (1), pp. vdaa165. Date of Electronic Publication: 2020 Dec 03 (Print Publication: 2021).