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pro vyhledávání: '"Horma Ghadially"'
Autor:
Horma Ghadially, Kristina M. Ilieva, Scott Mlynarski, Alwin Schuller, Theresa Proia, Wenlin Shao, Eric Gangl, Sharon Tentarelli, Aatman Doshi, Susan Cantin, Michael Secinaro, Yanjun Wang, Laura Prickett, Ray Finlay
Publikováno v:
Cancer Research. 80:4523-4523
The tumor microenvironment (TME) has multiple mechanisms of immune-suppression, one being recruitment of arginase (ARG) expressing myeloid cells. ARG is an enzyme that catalyzes hydrolysis of L-arginine into urea and L-ornithine. L-arginine is a semi